HK1075839A1 - Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride - Google Patents

Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride

Info

Publication number
HK1075839A1
HK1075839A1 HK05108042A HK05108042A HK1075839A1 HK 1075839 A1 HK1075839 A1 HK 1075839A1 HK 05108042 A HK05108042 A HK 05108042A HK 05108042 A HK05108042 A HK 05108042A HK 1075839 A1 HK1075839 A1 HK 1075839A1
Authority
HK
Hong Kong
Prior art keywords
indol
piperidin
ylmethyl
dione
pyridin
Prior art date
Application number
HK05108042A
Other languages
English (en)
Inventor
Bush Julie Kay
Faul Margaret Mary
Reutzel-Edens Susan Marie
Original Assignee
Lilly Co Eli
Lilly Corporate Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42799191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1075839(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli, Lilly Corporate Ct filed Critical Lilly Co Eli
Publication of HK1075839A1 publication Critical patent/HK1075839A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HK05108042A 2002-07-12 2005-09-14 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride HK1075839A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39597602P 2002-07-12 2002-07-12
PCT/US2003/019548 WO2004006928A1 (en) 2002-07-12 2003-07-08 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride

Publications (1)

Publication Number Publication Date
HK1075839A1 true HK1075839A1 (en) 2005-12-30

Family

ID=42799191

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05108042A HK1075839A1 (en) 2002-07-12 2005-09-14 Crystalline 2,5-dione-3-(1-methyl-1h-indol-3yl)-4-1-(pyridin-2-ylmethyl)piperidin-4-yl-1h-pyrrole mono-hydrochloride

Country Status (22)

Country Link
US (2) US8114901B2 (de)
EP (1) EP1523313B1 (de)
JP (2) JP4771356B2 (de)
KR (1) KR100687165B1 (de)
CN (1) CN100430058C (de)
AU (1) AU2003280958B9 (de)
CA (1) CA2393720C (de)
DE (1) DE60317675T2 (de)
EA (1) EA007463B1 (de)
EC (1) ECSP055537A (de)
ES (1) ES2295605T3 (de)
HK (1) HK1075839A1 (de)
HR (1) HRP20050035B1 (de)
IL (1) IL165747A (de)
NO (1) NO330254B1 (de)
NZ (1) NZ537137A (de)
PE (1) PE20040652A1 (de)
PL (1) PL373046A1 (de)
TW (1) TWI315667B (de)
UA (1) UA78801C2 (de)
WO (1) WO2004006928A1 (de)
ZA (1) ZA200500065B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101345002B1 (ko) 2005-01-21 2013-12-31 아스텍스 테라퓨틱스 리미티드 제약 화합물
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (de) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmazeutische kombinationen
WO2010101620A2 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
CN103068308B (zh) 2010-07-16 2016-03-16 第七感生物系统有限公司 用于流体传输装置的低压环境
AU2011308911B2 (en) * 2010-09-30 2014-10-02 Wisconsin Alumni Research Foundation (20R,25S)-2-methylene-19,26-dinor-1alpha, 25-dihydroxyvitamin D3 in crystalline form
CN103370007B (zh) 2010-11-09 2018-12-18 第七感生物系统有限公司 用于采血的系统和界面
EP2701598A1 (de) 2011-04-29 2014-03-05 Seventh Sense Biosystems, Inc. Systeme und verfahren zur flüssigkeitsentnahme aus einer person
ES2597081T3 (es) 2011-04-29 2017-01-13 Seventh Sense Biosystems, Inc. Entrega y/o recepción de fluidos
KR20190086655A (ko) 2016-06-17 2019-07-23 유니버시다드 데 로스 안데스 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도
BR112019002007B1 (pt) 2016-08-10 2024-01-16 F. Hoffmann-La Roche Ag Composição farmacêutica e uso de uma composição farmacêutica
JOP20190025A1 (ar) 2016-09-01 2019-02-19 Denovo Biopharma Llc طرق وتركيبة لتوقع نشاط إنزاستورين

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3625738A1 (de) 1986-07-30 1988-02-11 Goedecke Ag 2-acyloxypropylamin-derivate, verfahren zu deren herstellung und deren verwendung
US4808613A (en) 1986-11-21 1989-02-28 Bristol-Myers Company Rebeccamycin derivative containing pharmaceutical composition
US4785085A (en) 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
WO1988007045A1 (en) 1987-03-09 1988-09-22 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance k-252
DE3803620A1 (de) 1988-02-06 1989-08-17 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
CZ280738B6 (cs) 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
GB8904161D0 (en) 1989-02-23 1989-04-05 Hoffmann La Roche Substituted pyrroles
CA2015996C (en) 1989-05-05 2001-08-28 Hartmut Osswald Bis-(1h-indol-3-yl)-maleinimide derivatives and their use as pharmaceuticals
US5380746A (en) 1989-05-05 1995-01-10 Goedecke Aktiengesellschaft Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5489608A (en) 1989-12-21 1996-02-06 Goedecke Aktiengesellschaft Indolocarbazole derivatives and the use thereof
DE4005970A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4005969A1 (de) 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
CA2046801C (en) 1990-08-07 2002-02-26 Peter D. Davis Substituted pyrroles
US5292747A (en) 1990-08-07 1994-03-08 Hoffman-La Roche Inc. Substituted pyrroles
GB9123396D0 (en) 1991-11-04 1991-12-18 Hoffmann La Roche A process for the manufacture of substituted maleimides
US5461146A (en) 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
DE4243321A1 (de) 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US5484926A (en) 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
AU678435B2 (en) 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
SE501711C2 (sv) * 1993-09-08 1995-05-02 Jimek Int Ab Sprayrör för en duktvättanordning vid en tryckpress
US5624949A (en) 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
SI0817627T1 (de) 1993-12-23 2005-08-31 Lilly Co Eli
US5545636A (en) * 1993-12-23 1996-08-13 Eli Lilly And Company Protein kinase C inhibitors
US5481003A (en) 1994-06-22 1996-01-02 Eli Lilly And Company Protein kinase C inhibitors
PE91598A1 (es) 1996-07-29 1998-12-24 Hoffmann La Roche Pirroles sustituidos
GB9620390D0 (en) 1996-09-30 1996-11-13 Eisai London Res Lab Ltd Substances and their uses
EP1204656A2 (de) * 1999-07-29 2002-05-15 Eli Lilly And Company Eine kristalline form von 6-hydroxy-3-(4-[2-(piperidin-1-yl) ethoxy] phenoxy)-2-(4-methoxyphenyl) benzo[b]thiophen-hydrochlorid
AU1189201A (en) * 1999-10-22 2001-05-08 Eli Lilly And Company Therapeutic compositions including protein kinase c inhibitors
WO2002002094A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Use of a protein kinase c inhibitor to enhance the clinical efficacy of anti-neoplastic chemotherapeutic agents and radiation therapy
WO2002002116A2 (en) * 2000-06-29 2002-01-10 Eli Lilly And Company Therapeutic treatment of cancer with a protein kinase c inhibitor
WO2003104222A1 (en) * 2002-06-05 2003-12-18 Janssen Pharmaceutica N.V. Bisindolyl-maleimid derivatives as kinase inhibitors

Also Published As

Publication number Publication date
ECSP055537A (es) 2005-03-10
CN100430058C (zh) 2008-11-05
IL165747A0 (en) 2006-01-15
CA2393720A1 (en) 2004-01-16
KR20050021453A (ko) 2005-03-07
JP5242718B2 (ja) 2013-07-24
TW200408392A (en) 2004-06-01
DE60317675D1 (de) 2008-01-03
AU2003280958B9 (en) 2009-07-02
AU2003280958A1 (en) 2004-02-02
NO20050676L (no) 2005-02-09
AU2003280958B8 (en) 2009-02-19
US8114901B2 (en) 2012-02-14
EP1523313A1 (de) 2005-04-20
EP1523313B1 (de) 2007-11-21
DE60317675T2 (de) 2008-10-30
PL373046A1 (en) 2005-08-08
NO330254B1 (no) 2011-03-14
UA78801C2 (en) 2007-04-25
CA2393720C (en) 2010-09-14
HRP20050035B1 (hr) 2013-07-31
US20050288332A1 (en) 2005-12-29
JP2006502115A (ja) 2006-01-19
TWI315667B (en) 2009-10-11
JP4771356B2 (ja) 2011-09-14
CN1668304A (zh) 2005-09-14
ZA200500065B (en) 2006-03-29
NZ537137A (en) 2007-11-30
WO2004006928A1 (en) 2004-01-22
JP2011144182A (ja) 2011-07-28
PE20040652A1 (es) 2004-10-05
HRP20050035A2 (en) 2005-04-30
EA007463B1 (ru) 2006-10-27
US20070270465A1 (en) 2007-11-22
ES2295605T3 (es) 2008-04-16
IL165747A (en) 2010-05-17
KR100687165B1 (ko) 2007-02-27
EA200500191A1 (ru) 2005-06-30
AU2003280958B2 (en) 2008-12-18

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150708