NO330241B1 - Fremgangsmate for a identifisere forbindelser som endrer fosforylering av det humane klokkeproteinet hPERIODE1 (hPER1) - Google Patents
Fremgangsmate for a identifisere forbindelser som endrer fosforylering av det humane klokkeproteinet hPERIODE1 (hPER1) Download PDFInfo
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- NO330241B1 NO330241B1 NO20015972A NO20015972A NO330241B1 NO 330241 B1 NO330241 B1 NO 330241B1 NO 20015972 A NO20015972 A NO 20015972A NO 20015972 A NO20015972 A NO 20015972A NO 330241 B1 NO330241 B1 NO 330241B1
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- cell
- hckie
- protein
- hper1
- phosphorylation
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
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- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Electrophonic Musical Instruments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32774599A | 1999-06-08 | 1999-06-08 | |
| PCT/US2000/015633 WO2000075669A1 (en) | 1999-06-08 | 2000-06-07 | Screening methods for altering circadian rhythm proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20015972D0 NO20015972D0 (no) | 2001-12-06 |
| NO20015972L NO20015972L (no) | 2002-02-05 |
| NO330241B1 true NO330241B1 (no) | 2011-03-14 |
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| NO20015972A NO330241B1 (no) | 1999-06-08 | 2001-12-06 | Fremgangsmate for a identifisere forbindelser som endrer fosforylering av det humane klokkeproteinet hPERIODE1 (hPER1) |
| NO20100430A NO20100430L (no) | 1999-06-08 | 2010-03-23 | Anvendelse av en forbindelse for fremstilling av et medikament for a endre den cirkadiske rytme hos et pattedyr |
| NO20100431A NO20100431L (no) | 1999-06-08 | 2010-03-23 | Fremgangsmate for a endre degradering av det humane klokkeproteinet hPeriode1 (hPER1) |
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| NO20100430A NO20100430L (no) | 1999-06-08 | 2010-03-23 | Anvendelse av en forbindelse for fremstilling av et medikament for a endre den cirkadiske rytme hos et pattedyr |
| NO20100431A NO20100431L (no) | 1999-06-08 | 2010-03-23 | Fremgangsmate for a endre degradering av det humane klokkeproteinet hPeriode1 (hPER1) |
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| Country | Link |
|---|---|
| US (1) | US6555328B1 (ja) |
| EP (1) | EP1183541B1 (ja) |
| JP (1) | JP4583682B2 (ja) |
| KR (1) | KR100722176B1 (ja) |
| AT (1) | ATE322016T1 (ja) |
| AU (1) | AU767800B2 (ja) |
| BR (1) | BR0011437A (ja) |
| CA (1) | CA2375450C (ja) |
| DE (1) | DE60026998T2 (ja) |
| IL (2) | IL146729A0 (ja) |
| MX (1) | MXPA01011417A (ja) |
| NO (3) | NO330241B1 (ja) |
| NZ (1) | NZ514603A (ja) |
| WO (1) | WO2000075669A1 (ja) |
| ZA (1) | ZA200108962B (ja) |
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| US6436628B1 (en) | 1998-06-19 | 2002-08-20 | The Rockefeller University | Methods of identifying an agent which modulates period and doubletime protein interaction |
| US6476188B1 (en) | 1998-06-19 | 2002-11-05 | The Rockefeller University | Clock gene and methods of use thereof |
| ATE322016T1 (de) * | 1999-06-08 | 2006-04-15 | Aventis Pharma Inc | Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisse |
| EP1235915B1 (en) * | 1999-11-18 | 2009-05-27 | Mitsubishi Tanabe Pharma Corporation | Transgenic mammals into which a period 1 promoter that confers rhythmical expression has been introduced |
| GB0103110D0 (en) * | 2000-08-25 | 2001-03-28 | Aventis Pharma Inc | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| EP1358315A4 (en) * | 2001-01-11 | 2005-11-16 | Univ Utah Res Found | IDENTIFYING AN ADVANCED SLEEP PHASE SYNDROME GENE IN PEOPLE |
| AU2003278333A1 (en) * | 2002-10-25 | 2004-05-13 | University Of Surrey | Polymorphism in the per3 gene as a indicator in the diagnosis and treatment of circadian rhythm sleep disorders |
| WO2004050841A2 (en) * | 2002-11-27 | 2004-06-17 | University Of Utah Research Foundation | Casein kinase i epsilon and casein kinase i delta and sleep in humans |
| JO2629B1 (en) * | 2004-08-19 | 2012-06-24 | افينتيس فارما سوتيكالز انك | Branched carboxylic acid amides containing thienobirol, carboxylic acid amides containing pyrolithiazole, and the like as kinase inhibitors casein epsilon |
| EP1791537B1 (en) * | 2004-08-19 | 2009-10-14 | Aventis Pharmaceuticals, Inc. | 3-arylthioindole-2-carboxamide derivatives and analogs thereof as inhibitors of casein kinase i |
| JO2724B1 (en) | 2004-08-19 | 2013-09-15 | افينتس فارماسوتيكالز انك | 3-Alternative-5 -6-Amino Alkyl Indole-2-Carboxyl Acid Amide and Related Isotopes as Casein Kinase Inhibitors |
| JP2009538597A (ja) * | 2006-05-31 | 2009-11-12 | 独立行政法人放射線医学総合研究所 | 光誘導性周期的発現遺伝子及び体内時計システムに影響を与える物質のスクリーニング方法 |
| EP2077838B1 (en) * | 2006-10-25 | 2013-04-03 | The Rockefeller University | Methods for the treatment of amyloid-beta related disorders and compositions therefor |
| FR2918986B1 (fr) | 2007-07-19 | 2009-09-04 | Sanofi Aventis Sa | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique |
| CN105744948B (zh) * | 2013-10-14 | 2020-03-24 | 南京大学 | 进食节律提前综合征的识别方法及其应用 |
| KR101600144B1 (ko) | 2013-12-20 | 2016-03-04 | 서울대학교산학협력단 | 일주기 리듬 수면장애 및 시차 부적응에 대한 예방 또는 치료제 스크리닝 방법 |
| AU2015204566A1 (en) | 2014-01-09 | 2016-08-25 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US11116754B2 (en) | 2015-11-13 | 2021-09-14 | The Trustees Of Columbia University In The City Of New York | Inhibition of TOR complex 2 increases immunity against bacterial infection |
| WO2023129377A1 (en) * | 2022-01-03 | 2023-07-06 | The Johns Hopkins University | Methods and materials for treating heart attack |
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| JPH1157137A (ja) * | 1997-08-28 | 1999-03-02 | Sanyo Bussan Kk | 遊技機用特別図柄表示装置 |
| KR100246893B1 (ko) * | 1997-12-29 | 2000-05-01 | 윤종용 | 전자렌지용 도어 |
| WO1999057137A1 (en) * | 1998-05-07 | 1999-11-11 | The President & Fellows Of Harvard College | Compositions and methods involving regulation of mammalian circadian rhythms |
| ATE322016T1 (de) * | 1999-06-08 | 2006-04-15 | Aventis Pharma Inc | Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisse |
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- 2000-06-07 US US09/589,462 patent/US6555328B1/en not_active Expired - Lifetime
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- 2000-06-07 KR KR1020017015764A patent/KR100722176B1/ko not_active IP Right Cessation
- 2000-06-07 JP JP2001501893A patent/JP4583682B2/ja not_active Expired - Fee Related
- 2000-06-07 EP EP00939629A patent/EP1183541B1/en not_active Expired - Lifetime
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| ATE322016T1 (de) | 2006-04-15 |
| BR0011437A (pt) | 2002-03-05 |
| ZA200108962B (en) | 2003-01-30 |
| NO20100431L (no) | 2002-02-05 |
| CA2375450A1 (en) | 2000-12-14 |
| CA2375450C (en) | 2009-04-28 |
| JP2003501074A (ja) | 2003-01-14 |
| JP4583682B2 (ja) | 2010-11-17 |
| NO20015972D0 (no) | 2001-12-06 |
| IL146729A0 (en) | 2002-07-25 |
| MXPA01011417A (es) | 2002-06-04 |
| KR100722176B1 (ko) | 2007-05-29 |
| EP1183541A1 (en) | 2002-03-06 |
| NZ514603A (en) | 2003-10-31 |
| AU767800B2 (en) | 2003-11-27 |
| IL146729A (en) | 2007-06-17 |
| NO20100430L (no) | 2002-02-05 |
| EP1183541B1 (en) | 2006-03-29 |
| AU5468900A (en) | 2000-12-28 |
| DE60026998T2 (de) | 2007-04-05 |
| WO2000075669A1 (en) | 2000-12-14 |
| US6555328B1 (en) | 2003-04-29 |
| KR20020033101A (ko) | 2002-05-04 |
| DE60026998D1 (de) | 2006-05-18 |
| NO20015972L (no) | 2002-02-05 |
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