NO327446B1 - Anvendelse av en forbindelse som har angiotensin II antagonistisk aktivitet, et prodrug derav eller et salt derav. - Google Patents
Anvendelse av en forbindelse som har angiotensin II antagonistisk aktivitet, et prodrug derav eller et salt derav. Download PDFInfo
- Publication number
- NO327446B1 NO327446B1 NO20015257A NO20015257A NO327446B1 NO 327446 B1 NO327446 B1 NO 327446B1 NO 20015257 A NO20015257 A NO 20015257A NO 20015257 A NO20015257 A NO 20015257A NO 327446 B1 NO327446 B1 NO 327446B1
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- Norway
- Prior art keywords
- group
- compound
- angiotensin
- antagonistic activity
- use according
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12149899 | 1999-04-28 | ||
| PCT/JP2000/002766 WO2000066161A1 (fr) | 1999-04-28 | 2000-04-27 | Preventifs / remedes / inhibiteurs de progression pour retinopathie simplex ou retinopathie preproliferante |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20015257L NO20015257L (no) | 2001-10-26 |
| NO20015257D0 NO20015257D0 (no) | 2001-10-26 |
| NO327446B1 true NO327446B1 (no) | 2009-06-29 |
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| NO20015257A NO327446B1 (no) | 1999-04-28 | 2001-10-26 | Anvendelse av en forbindelse som har angiotensin II antagonistisk aktivitet, et prodrug derav eller et salt derav. |
Country Status (23)
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| US (2) | US7064141B1 (zh) |
| EP (1) | EP1197223B1 (zh) |
| KR (1) | KR100865059B1 (zh) |
| CN (1) | CN1172719C (zh) |
| AT (1) | ATE289204T1 (zh) |
| AU (1) | AU774799B2 (zh) |
| BR (1) | BR0010084A (zh) |
| CA (1) | CA2371554C (zh) |
| CZ (1) | CZ301913B6 (zh) |
| DE (1) | DE60018186T2 (zh) |
| DK (1) | DK1197223T3 (zh) |
| ES (1) | ES2233362T3 (zh) |
| HU (1) | HU226948B1 (zh) |
| MX (1) | MXPA01010923A (zh) |
| NO (1) | NO327446B1 (zh) |
| NZ (1) | NZ514855A (zh) |
| PL (1) | PL196895B1 (zh) |
| PT (1) | PT1197223E (zh) |
| RU (1) | RU2239454C2 (zh) |
| SI (1) | SI1197223T1 (zh) |
| SK (1) | SK286859B6 (zh) |
| WO (1) | WO2000066161A1 (zh) |
| ZA (1) | ZA200108527B (zh) |
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| JP4484427B2 (ja) * | 2001-12-03 | 2010-06-16 | 武田薬品工業株式会社 | インスリン抵抗性改善剤 |
| WO2003047573A1 (fr) * | 2001-12-03 | 2003-06-12 | Takeda Chemical Industries, Ltd. | Agents pour améliorer l'état de résistance à l'insuline |
| TW200304812A (en) * | 2002-03-08 | 2003-10-16 | Sankyo Co | An eye drop containing a tetrazole derivative |
| US8980870B2 (en) | 2002-09-24 | 2015-03-17 | Boehringer Ingelheim International Gmbh | Solid telmisartan pharmaceutical formulations |
| DE10335027A1 (de) * | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| EP1614428A4 (en) * | 2003-04-15 | 2010-01-06 | Sankyo Co | MEDICAMENT FOR THE PREVENTION OR TREATMENT OF ANGIOGENIC OCULAR DISEASES |
| US20050038093A1 (en) * | 2003-05-02 | 2005-02-17 | Boehringer Ingelheim International Gmbh | Treating diabetic retinopathy with angiotensin II receptor blockers |
| KR20070083538A (ko) * | 2004-08-31 | 2007-08-24 | 뉴사우스 이노베이션즈 피티와이 리미티드 | Ｖｅｇｆ 억제 |
| JP5134963B2 (ja) * | 2004-11-05 | 2013-01-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | テルミサルタンとアムロジピンを含む二層錠剤 |
| CN101163474B (zh) * | 2005-04-21 | 2012-02-22 | 参天制药株式会社 | 角膜结膜病变治疗剂 |
| RU2423127C2 (ru) * | 2005-12-06 | 2011-07-10 | Сантен Фармасьютикал Ко., Лтд. | Терапевтическое средство против роговично-конъюнктивального нарушения |
| PT2124903T (pt) * | 2007-03-28 | 2019-09-26 | Takeda Pharmaceuticals Co | Composição farmacêutica sólida compreendendo um derivado de benzimidazole-7-carboxilato e um agente de controlo de ph |
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| GB9027211D0 (en) * | 1990-12-14 | 1991-02-06 | Smithkline Beecham Plc | Medicaments |
| US5591762A (en) | 1991-02-06 | 1997-01-07 | Dr. Karl Thomae Gmbh | Benzimidazoles useful as angiotensin-11 antagonists |
| DE4201554A1 (de) | 1992-01-22 | 1993-07-29 | Thomae Gmbh Dr K | Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| GB9110635D0 (en) | 1991-05-16 | 1991-07-03 | Glaxo Group Ltd | Chemical compounds |
| IL104755A0 (en) | 1992-02-17 | 1993-06-10 | Ciba Geigy Ag | Treatment of glaucoma |
| GB9223860D0 (en) | 1992-11-13 | 1993-01-06 | Glaxo Group Ltd | Chemical compounds |
| CZ154994A3 (en) * | 1993-07-02 | 1995-09-13 | Senju Pharma Co | Visual hypotensive agent |
| JPH0789957A (ja) | 1993-09-22 | 1995-04-04 | Nissan Chem Ind Ltd | ビフェニルメチルアミン誘導体 |
| CA2181461A1 (en) * | 1994-02-08 | 1995-08-17 | Alica Huxley | Treatment of normotensive glaucoma with angiotensin ii antagonists |
| JPH09210183A (ja) * | 1996-01-31 | 1997-08-12 | Suzuki Motor Corp | 動力伝達装置 |
| RO118870B1 (ro) * | 1996-03-29 | 2003-12-30 | Smithkline Beecham Corporation | Monometansulfonat de acid (e)-alfa-[2-n-butil-1-[(4-carboxifenil)metil]-1h-imidazol-5-il]metilen-2-tiofenpropionic, procedee de preparare şi compoziţii farmaceutice |
| KR20050047560A (ko) | 1996-04-05 | 2005-05-20 | 다께다 케미칼 인더스트리즈,리미티드 | 안지오텐신 ⅱ 및 길항 활성을 갖는 화합물을 함유하는약제학적 조합물 |
| TW416953B (en) * | 1996-09-25 | 2001-01-01 | Takeda Chemical Industries Ltd | Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use |
| EP0855392A3 (de) | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE69807695T2 (de) * | 1997-06-27 | 2003-07-31 | Smithkline Beecham Corp | Eprosartan-monohydrate |
| IT1292437B1 (it) * | 1997-06-30 | 1999-02-08 | Zambon Spa | Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti |
| PL198875B1 (pl) * | 1997-08-06 | 2008-07-31 | Smithkline Beecham Corp | Kompleks kwasu (E)-α-[2-n-butylo-1-[(4-karboksyfenylo)metylo]-1H-imidazol-5-ilo]metyleno-2-tiofenopropionowego arginylu, sposób jego wytwarzania, kompozycja farmaceutyczna zawierajaca ten związek oraz jego zastosowanie |
| ES2214013T3 (es) | 1998-03-04 | 2004-09-01 | Takeda Chemical Industries Ltd | Preparacion de liberacion sostenida para un antagonista de aii, su produccion y su uso. |
| JP2002520274A (ja) | 1998-07-10 | 2002-07-09 | ノバルティス アクチエンゲゼルシャフト | バルサルタンとカルシウムチャンネルブロッカーの抗高血圧組合わせ |
| FR2783422A1 (fr) | 1998-09-21 | 2000-03-24 | Sanofi Sa | Composition pharmaceutique contenant un antagoniste des recepteurs at1 de l'angiotensine ii et un antiagregant plaquettaire |
| JP2000159671A (ja) | 1998-12-01 | 2000-06-13 | Takeda Chem Ind Ltd | 血管新生阻害剤 |
-
2000
- 2000-04-27 RU RU2001132073/15A patent/RU2239454C2/ru not_active IP Right Cessation
- 2000-04-27 CA CA002371554A patent/CA2371554C/en not_active Expired - Fee Related
- 2000-04-27 CZ CZ20013804A patent/CZ301913B6/cs not_active IP Right Cessation
- 2000-04-27 DE DE60018186T patent/DE60018186T2/de not_active Expired - Lifetime
- 2000-04-27 KR KR1020017013765A patent/KR100865059B1/ko not_active IP Right Cessation
- 2000-04-27 PL PL350554A patent/PL196895B1/pl not_active IP Right Cessation
- 2000-04-27 SI SI200030651T patent/SI1197223T1/xx unknown
- 2000-04-27 AU AU41434/00A patent/AU774799B2/en not_active Ceased
- 2000-04-27 PT PT00921056T patent/PT1197223E/pt unknown
- 2000-04-27 SK SK1545-2001A patent/SK286859B6/sk not_active IP Right Cessation
- 2000-04-27 WO PCT/JP2000/002766 patent/WO2000066161A1/ja active IP Right Grant
- 2000-04-27 MX MXPA01010923A patent/MXPA01010923A/es active IP Right Grant
- 2000-04-27 DK DK00921056T patent/DK1197223T3/da active
- 2000-04-27 US US09/958,740 patent/US7064141B1/en not_active Expired - Fee Related
- 2000-04-27 NZ NZ514855A patent/NZ514855A/xx not_active IP Right Cessation
- 2000-04-27 CN CNB008067783A patent/CN1172719C/zh not_active Expired - Fee Related
- 2000-04-27 EP EP00921056A patent/EP1197223B1/en not_active Expired - Lifetime
- 2000-04-27 BR BR0010084-6A patent/BR0010084A/pt not_active Application Discontinuation
- 2000-04-27 ES ES00921056T patent/ES2233362T3/es not_active Expired - Lifetime
- 2000-04-27 HU HU0200890A patent/HU226948B1/hu not_active IP Right Cessation
- 2000-04-27 AT AT00921056T patent/ATE289204T1/de not_active IP Right Cessation
-
2001
- 2001-10-17 ZA ZA200108527A patent/ZA200108527B/en unknown
- 2001-10-26 NO NO20015257A patent/NO327446B1/no not_active IP Right Cessation
-
2006
- 2006-04-19 US US11/406,345 patent/US20060189669A1/en not_active Abandoned
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