NO324531B1 - Enhetsdose av sammensetning omfattende en proteinaseinhibitor som er N-tert-butyl-dekahydro-2-[2(R)-hydroksy-4-fenyl-3(S)-[[N-(2-kinolylkarbonyl)-L-asparaginyl]amino]butyl]-(4aS, 8aS)-isokinolin-3(S)-karboksamid og et monoglyserid. - Google Patents
Enhetsdose av sammensetning omfattende en proteinaseinhibitor som er N-tert-butyl-dekahydro-2-[2(R)-hydroksy-4-fenyl-3(S)-[[N-(2-kinolylkarbonyl)-L-asparaginyl]amino]butyl]-(4aS, 8aS)-isokinolin-3(S)-karboksamid og et monoglyserid. Download PDFInfo
- Publication number
- NO324531B1 NO324531B1 NO19975665A NO975665A NO324531B1 NO 324531 B1 NO324531 B1 NO 324531B1 NO 19975665 A NO19975665 A NO 19975665A NO 975665 A NO975665 A NO 975665A NO 324531 B1 NO324531 B1 NO 324531B1
- Authority
- NO
- Norway
- Prior art keywords
- monoglyceride
- butyl
- proteinase inhibitor
- composition
- phenyl
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46849395A | 1995-06-06 | 1995-06-06 | |
| US08/616,233 US6008228A (en) | 1995-06-06 | 1996-05-07 | Pharmaceutical compositions containing proteinase inhibitors |
| PCT/EP1996/002431 WO1996039142A1 (en) | 1995-06-06 | 1996-06-04 | Pharmaceutical composition comprising a proteinase inhibitor and a monoglyceride |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975665D0 NO975665D0 (no) | 1997-12-05 |
| NO975665L NO975665L (no) | 1998-02-05 |
| NO324531B1 true NO324531B1 (no) | 2007-11-12 |
Family
ID=27042422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19975665A NO324531B1 (no) | 1995-06-06 | 1997-12-05 | Enhetsdose av sammensetning omfattende en proteinaseinhibitor som er N-tert-butyl-dekahydro-2-[2(R)-hydroksy-4-fenyl-3(S)-[[N-(2-kinolylkarbonyl)-L-asparaginyl]amino]butyl]-(4aS, 8aS)-isokinolin-3(S)-karboksamid og et monoglyserid. |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0831826B1 (de) |
| JP (1) | JP3238412B2 (de) |
| CN (1) | CN1092960C (de) |
| AT (1) | ATE226075T1 (de) |
| AU (1) | AU709796B2 (de) |
| BG (1) | BG63711B1 (de) |
| BR (1) | BR9610842A (de) |
| CA (1) | CA2224125C (de) |
| CY (1) | CY2373B1 (de) |
| CZ (1) | CZ292192B6 (de) |
| DE (1) | DE69624354T2 (de) |
| DK (1) | DK0831826T3 (de) |
| EA (1) | EA001413B1 (de) |
| ES (1) | ES2182996T3 (de) |
| HK (1) | HK1010136A1 (de) |
| HU (1) | HU223899B1 (de) |
| IL (1) | IL122353A0 (de) |
| IS (1) | IS2661B (de) |
| MX (1) | MX9709193A (de) |
| NO (1) | NO324531B1 (de) |
| NZ (1) | NZ311646A (de) |
| OA (1) | OA10546A (de) |
| PL (1) | PL184820B1 (de) |
| PT (1) | PT831826E (de) |
| SK (1) | SK282121B6 (de) |
| TR (1) | TR199701541T1 (de) |
| WO (1) | WO1996039142A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2203648C2 (ru) | 1997-07-29 | 2003-05-10 | Фармация Энд Апджон Компани | Самоэмульгирующаяся композиция для липофильных соединений |
| PT989851E (pt) | 1997-07-29 | 2002-12-31 | Upjohn Co | Formulacao auto-emulsionante para compostos lipofilicos acidicos |
| CN1232244C (zh) * | 1999-02-08 | 2005-12-21 | 阿尔萨公司 | 稳定的非水性单相粘性载体及采用该载体的制剂 |
| US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
| US7919109B2 (en) | 1999-02-08 | 2011-04-05 | Intarcia Therapeutics, Inc. | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
| US6956048B2 (en) | 1999-03-31 | 2005-10-18 | Pharmacia & Upjohn Company | Pharmaceutical emulsions for retroviral protease inhibitors |
| US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| BR0202252A (pt) | 2002-06-12 | 2004-06-29 | Cristalia Prod Quimicos Farm | Composição farmacêutica solúvel estável para administração de inibidores da hiv protease e processo de obtenção de composições farmacêuticas concentradas para a administração de inibidores da hiv protease |
| US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
| WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
| US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
| DK2020990T3 (da) | 2006-05-30 | 2010-12-13 | Intarcia Therapeutics Inc | Strømningsmodulator med en indre kanal til et todelt osmotisk fremføringssystem |
| CN101715340A (zh) | 2007-04-23 | 2010-05-26 | 精达制药公司 | 促胰岛素释放肽的混悬制剂及其应用 |
| WO2009102467A2 (en) | 2008-02-13 | 2009-08-20 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
| EP2108705A1 (de) | 2008-04-08 | 2009-10-14 | Universität Duisburg-Essen | Verfahren zur Analyse der epigenetischen Lage des HtrA1 Gens in einer biologischen Probe |
| JP5718925B2 (ja) | 2009-09-28 | 2015-05-13 | インターシア セラピューティクス，インコーポレイティド | 実質的な定常状態薬物送達の迅速な確立及び／又は停止 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
| WO2016196851A2 (en) | 2015-06-03 | 2016-12-08 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
| WO2017200943A1 (en) | 2016-05-16 | 2017-11-23 | Intarcia Therapeutics, Inc. | Glucagon-receptor selective polypeptides and methods of use thereof |
| USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
| USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
| KR20190104039A (ko) | 2017-01-03 | 2019-09-05 | 인타르시아 세라퓨틱스 인코포레이티드 | Glp-1 수용체 효능제의 연속적인 투여 및 약물의 동시-투여를 포함하는 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8927913D0 (en) * | 1989-12-11 | 1990-02-14 | Hoffmann La Roche | Amino acid derivatives |
| IL110752A (en) * | 1993-09-13 | 2000-07-26 | Abbott Lab | Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor |
-
1996
- 1996-06-04 CN CN96194327A patent/CN1092960C/zh not_active Expired - Lifetime
- 1996-06-04 MX MX9709193A patent/MX9709193A/es unknown
- 1996-06-04 TR TR97/01541T patent/TR199701541T1/xx unknown
- 1996-06-04 WO PCT/EP1996/002431 patent/WO1996039142A1/en active IP Right Grant
- 1996-06-04 IL IL12235396A patent/IL122353A0/xx not_active IP Right Cessation
- 1996-06-04 DE DE69624354T patent/DE69624354T2/de not_active Expired - Lifetime
- 1996-06-04 AT AT96921929T patent/ATE226075T1/de active
- 1996-06-04 CA CA002224125A patent/CA2224125C/en not_active Expired - Lifetime
- 1996-06-04 PL PL96323860A patent/PL184820B1/pl unknown
- 1996-06-04 EA EA199800023A patent/EA001413B1/ru not_active IP Right Cessation
- 1996-06-04 DK DK96921929T patent/DK0831826T3/da active
- 1996-06-04 EP EP96921929A patent/EP0831826B1/de not_active Expired - Lifetime
- 1996-06-04 HU HU9801905A patent/HU223899B1/hu active IP Right Grant
- 1996-06-04 NZ NZ311646A patent/NZ311646A/en not_active IP Right Cessation
- 1996-06-04 BR BR9610842A patent/BR9610842A/pt not_active IP Right Cessation
- 1996-06-04 CZ CZ19973803A patent/CZ292192B6/cs not_active IP Right Cessation
- 1996-06-04 PT PT96921929T patent/PT831826E/pt unknown
- 1996-06-04 SK SK1627-97A patent/SK282121B6/sk not_active IP Right Cessation
- 1996-06-04 AU AU63004/96A patent/AU709796B2/en not_active Expired
- 1996-06-04 JP JP50014397A patent/JP3238412B2/ja not_active Expired - Lifetime
- 1996-06-04 ES ES96921929T patent/ES2182996T3/es not_active Expired - Lifetime
-
1997
- 1997-12-04 IS IS4627A patent/IS2661B/is unknown
- 1997-12-05 NO NO19975665A patent/NO324531B1/no not_active IP Right Cessation
- 1997-12-05 BG BG102106A patent/BG63711B1/bg unknown
- 1997-12-05 OA OA70151A patent/OA10546A/en unknown
-
1998
- 1998-09-09 HK HK98110542A patent/HK1010136A1/xx not_active IP Right Cessation
-
2003
- 2003-08-22 CY CY0300057A patent/CY2373B1/xx unknown
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Legal Events
| Date | Code | Title | Description |
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| MK1K | Patent expired |