NO321769B1 - Oksygenredusert vandig opplosning av faktor VIII og fremgangsmate for fremstilling av denne. - Google Patents
Oksygenredusert vandig opplosning av faktor VIII og fremgangsmate for fremstilling av denne. Download PDFInfo
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- NO321769B1 NO321769B1 NO19954457A NO954457A NO321769B1 NO 321769 B1 NO321769 B1 NO 321769B1 NO 19954457 A NO19954457 A NO 19954457A NO 954457 A NO954457 A NO 954457A NO 321769 B1 NO321769 B1 NO 321769B1
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- Prior art keywords
- factor viii
- aqueous solution
- solution
- formulation according
- inert gas
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939301581A SE9301581D0 (sv) | 1993-05-07 | 1993-05-07 | Protein formulation |
PCT/SE1994/000265 WO1994026286A1 (en) | 1993-05-07 | 1994-03-24 | Oxygen-reduced aqueous solution of factor viii |
Publications (3)
Publication Number | Publication Date |
---|---|
NO954457D0 NO954457D0 (no) | 1995-11-07 |
NO954457L NO954457L (no) | 1995-11-07 |
NO321769B1 true NO321769B1 (no) | 2006-07-03 |
Family
ID=20389868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19954457A NO321769B1 (no) | 1993-05-07 | 1995-11-07 | Oksygenredusert vandig opplosning av faktor VIII og fremgangsmate for fremstilling av denne. |
Country Status (24)
Country | Link |
---|---|
US (1) | US5962650A (sv) |
EP (1) | EP0700299B1 (sv) |
JP (1) | JP3751633B2 (sv) |
KR (1) | KR100304143B1 (sv) |
CN (1) | CN1113655C (sv) |
AT (1) | ATE218354T1 (sv) |
AU (1) | AU681883B2 (sv) |
CA (1) | CA2161350C (sv) |
CZ (1) | CZ293527B6 (sv) |
DE (1) | DE69430745T2 (sv) |
DK (1) | DK0700299T3 (sv) |
EE (1) | EE03118B1 (sv) |
ES (1) | ES2177579T3 (sv) |
FI (1) | FI111910B (sv) |
HU (1) | HU215263B (sv) |
NO (1) | NO321769B1 (sv) |
NZ (1) | NZ266031A (sv) |
PL (1) | PL174866B1 (sv) |
PT (1) | PT700299E (sv) |
RU (1) | RU2142290C1 (sv) |
SE (1) | SE9301581D0 (sv) |
SK (1) | SK283002B6 (sv) |
WO (1) | WO1994026286A1 (sv) |
ZA (1) | ZA942251B (sv) |
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JP3466516B2 (ja) | 1999-09-07 | 2003-11-10 | 科学技術振興事業団 | 安定保存可能な酸素輸液剤 |
AU2002351756A1 (en) | 2001-12-21 | 2003-07-15 | Novo Nordisk Health Care Ag | Liquid composition of factor vii polypeptides |
IL162618A0 (en) * | 2001-12-21 | 2005-11-20 | Novo Nordisk As | Liquid composition of modified factor vii polypeptides |
GB0207092D0 (en) | 2002-03-26 | 2002-05-08 | Sod Conseils Rech Applic | Stable pharmaceutical composition containing factor VIII |
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US7897734B2 (en) | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
AU2004241698A1 (en) * | 2003-05-23 | 2004-12-02 | Novo Nordisk Health Care Ag | Protein stabilization in solution |
ES2382157T3 (es) * | 2003-06-25 | 2012-06-05 | Novo Nordisk Health Care Ag | Composición líquida de polipépttidos del factor VII |
JP5306597B2 (ja) * | 2003-07-01 | 2013-10-02 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 第vii因子ポリペプチドの液体水性薬学的組成物 |
ES2574581T3 (es) | 2003-08-14 | 2016-06-20 | Novo Nordisk Health Care Ag | Composición farmacéutica líquida acuosa de polipéptidos de tipo Factor VII |
TR201809670T4 (tr) | 2003-12-19 | 2018-07-23 | Novo Nordisk Healthcare Ag | Faktör VII polipeptitlerinin stabilize edilmiş kompozisyonları. |
WO2005107776A1 (en) * | 2004-05-03 | 2005-11-17 | Emory University | METHOD OF ADMINISTERING PORCINE B-DOMAINLESS fVIII |
US7494974B2 (en) | 2006-10-24 | 2009-02-24 | Ikor, Inc. | Carboxymethylated cross-linked tetrameric hemoglobin |
US7504377B2 (en) | 2006-10-23 | 2009-03-17 | Ikor, Inc. | Nitric oxide-blocked cross-linked tetrameric hemoglobin |
PT1982731E (pt) * | 2007-04-17 | 2010-07-06 | Schwabe Willmar Gmbh & Co | PROCESSO PARA PRODUÃO DE SOLUÃES DE EXTRACTOS DE PELARGËNIO ESTáVEIS EM ARMAZENAMENTO |
ATE503763T1 (de) * | 2007-07-11 | 2011-04-15 | Novo Nordisk As | Aufreinigung von faktor viii unter verwendung eines mixed-mode oder multimodalen harzes |
EP2113564A1 (en) | 2008-05-01 | 2009-11-04 | Arecor Limited | Protein formulation |
JP2012500250A (ja) | 2008-08-21 | 2012-01-05 | オクタファルマ アクチェン ゲゼルシャフト | 組換えにより産生したヒト第viii及び第ix因子 |
KR101691443B1 (ko) * | 2008-09-03 | 2016-12-30 | 옥타파마 아게 | 재조합에 의해 제조된 인자 ⅷ을 위한 신규한 보호 조성물 |
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US10172949B2 (en) | 2009-06-09 | 2019-01-08 | Prolong Pharmaceuticals, LLC | Hemoglobin compositions |
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-
1993
- 1993-05-07 SE SE19939301581A patent/SE9301581D0/sv unknown
-
1994
- 1994-03-24 PT PT94915307T patent/PT700299E/pt unknown
- 1994-03-24 PL PL94311567A patent/PL174866B1/pl not_active IP Right Cessation
- 1994-03-24 CN CN94192021A patent/CN1113655C/zh not_active Expired - Fee Related
- 1994-03-24 EP EP94915307A patent/EP0700299B1/en not_active Expired - Lifetime
- 1994-03-24 SK SK1383-95A patent/SK283002B6/sk not_active IP Right Cessation
- 1994-03-24 JP JP52470394A patent/JP3751633B2/ja not_active Expired - Fee Related
- 1994-03-24 HU HU9503171A patent/HU215263B/hu not_active IP Right Cessation
- 1994-03-24 WO PCT/SE1994/000265 patent/WO1994026286A1/en active IP Right Grant
- 1994-03-24 NZ NZ266031A patent/NZ266031A/en not_active IP Right Cessation
- 1994-03-24 AU AU66597/94A patent/AU681883B2/en not_active Ceased
- 1994-03-24 DE DE69430745T patent/DE69430745T2/de not_active Expired - Lifetime
- 1994-03-24 US US08/535,251 patent/US5962650A/en not_active Expired - Lifetime
- 1994-03-24 AT AT94915307T patent/ATE218354T1/de active
- 1994-03-24 KR KR1019950704933A patent/KR100304143B1/ko not_active IP Right Cessation
- 1994-03-24 CZ CZ19952869A patent/CZ293527B6/cs not_active IP Right Cessation
- 1994-03-24 CA CA002161350A patent/CA2161350C/en not_active Expired - Fee Related
- 1994-03-24 DK DK94915307T patent/DK0700299T3/da active
- 1994-03-24 RU RU95121755A patent/RU2142290C1/ru not_active IP Right Cessation
- 1994-03-24 ES ES94915307T patent/ES2177579T3/es not_active Expired - Lifetime
- 1994-04-02 ZA ZA942251A patent/ZA942251B/xx unknown
- 1994-11-17 EE EE9400380A patent/EE03118B1/xx not_active IP Right Cessation
-
1995
- 1995-11-06 FI FI955305A patent/FI111910B/sv not_active IP Right Cessation
- 1995-11-07 NO NO19954457A patent/NO321769B1/no not_active IP Right Cessation
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