NO320839B1 - Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. - Google Patents
Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. Download PDFInfo
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- NO320839B1 NO320839B1 NO19974035A NO974035A NO320839B1 NO 320839 B1 NO320839 B1 NO 320839B1 NO 19974035 A NO19974035 A NO 19974035A NO 974035 A NO974035 A NO 974035A NO 320839 B1 NO320839 B1 NO 320839B1
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- 210000000584 nodose ganglion Anatomy 0.000 description 1
- 229920002113 octoxynol Polymers 0.000 description 1
- 230000002018 overexpression Effects 0.000 description 1
- 230000007030 peptide scission Effects 0.000 description 1
- 210000002856 peripheral neuron Anatomy 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 208000028591 pheochromocytoma Diseases 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000028742 placenta development Effects 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 239000002797 plasminogen activator inhibitor Substances 0.000 description 1
- 108010055896 polyornithine Proteins 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000019705 regulation of vascular permeability Effects 0.000 description 1
- 230000002629 repopulating effect Effects 0.000 description 1
- 230000007441 retrograde transport Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 108091092562 ribozyme Proteins 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 229940016590 sarkosyl Drugs 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 210000002363 skeletal muscle cell Anatomy 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 210000003594 spinal ganglia Anatomy 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 150000004992 toluidines Chemical class 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- 235000011178 triphosphate Nutrition 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 230000002227 vasoactive effect Effects 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPN1457A AUPN145795A0 (en) | 1995-03-02 | 1995-03-02 | A novel growth factor and a genetic sequence encoding same |
| AUPN6647A AUPN664795A0 (en) | 1995-11-20 | 1995-11-20 | A novel growth factor and a genetic sequence encoding same |
| AUPN7274A AUPN727495A0 (en) | 1995-12-22 | 1995-12-22 | A novel growth factor and a genetic sequence encoding same-II |
| PCT/AU1996/000094 WO1996027007A1 (en) | 1995-03-02 | 1996-02-22 | A novel growth factor and a genetic sequence encoding same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974035D0 NO974035D0 (no) | 1997-09-02 |
| NO974035L NO974035L (no) | 1997-11-03 |
| NO320839B1 true NO320839B1 (no) | 2006-01-30 |
Family
ID=27157841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19974035A NO320839B1 (no) | 1995-03-02 | 1997-09-02 | Isolert polypeptid, fremgangsmate for dets fremstilling, isolert nukleinsyremolekyl, isolert antistoff, antisensemolekyl, preparat, anvendelse av henholdsvis et polypeptid og et nukleinsyremolekyl, vertscelle samt vektor. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070135344A1 (ja) |
| EP (1) | EP0815221B1 (ja) |
| JP (2) | JPH11500139A (ja) |
| KR (1) | KR100414615B1 (ja) |
| CN (1) | CN1194090C (ja) |
| AT (1) | ATE252600T1 (ja) |
| BR (1) | BR9607628A (ja) |
| CA (1) | CA2214439C (ja) |
| DE (1) | DE69630442T2 (ja) |
| ES (1) | ES2206558T3 (ja) |
| FI (1) | FI120153B (ja) |
| HK (1) | HK1002963A1 (ja) |
| HU (1) | HU223438B1 (ja) |
| NO (1) | NO320839B1 (ja) |
| NZ (2) | NZ337634A (ja) |
| WO (1) | WO1996027007A1 (ja) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5928939A (en) | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
| EP0873348A4 (en) * | 1995-06-06 | 2000-11-08 | Human Genome Sciences Inc | GROWTH FACTOR 3 OF THE HUMAN VASCULAR ENDOTHELIUM |
| EP0848755B2 (en) | 1995-09-08 | 2011-02-09 | Genentech, Inc. | Vegf-related protein |
| JP4086315B2 (ja) | 1995-09-29 | 2008-05-14 | ユニベルシタ デグリ スチュディ ディ シエナ | 調節遺伝子およびその使用 |
| US6994989B1 (en) | 1995-11-08 | 2006-02-07 | Immunex Corp. | FLK-1 binding proteins |
| WO1997017442A1 (en) | 1995-11-08 | 1997-05-15 | Immunex Corporation | Flk-1 binding protein |
| ES2251740T3 (es) | 1996-08-23 | 2006-05-01 | Ludwig Institute For Cancer Research | Factor de crecimiento de celulas de endotelio vascular d recombinante (vegf-d). |
| CA2287538A1 (en) * | 1997-04-25 | 1998-11-05 | Collateral Therapeutics | Truncated vegf-related proteins |
| IL137616A0 (en) | 1998-02-06 | 2001-07-24 | Collateral Therapeutics Inc | Variants of vegf-a |
| US7105481B2 (en) | 1998-11-10 | 2006-09-12 | Ludwig Institute For Cancer Research | Method for stimulating connective tissue growth or wound healing |
| NZ511379A (en) | 1998-11-10 | 2003-06-30 | Ludwig Inst Cancer Res | Platelet-derived growth factor D (PDGF-D), DNA coding therefor, and uses thereof for invasions of tumor cells |
| WO2000034474A2 (en) | 1998-12-07 | 2000-06-15 | Zymogenetics, Inc. | Growth factor homolog zvegf3 |
| US6783953B1 (en) | 1998-12-22 | 2004-08-31 | Janssen Pharmaceutica N.V. | Vascular endothelial growth factor-X |
| AUPQ568100A0 (en) * | 2000-02-16 | 2000-03-09 | Amrad Operations Pty. Limited | A method for producing recombinant molecules |
| US7026462B2 (en) | 2000-12-07 | 2006-04-11 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
| US7067317B2 (en) | 2000-12-07 | 2006-06-27 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
| US7981863B2 (en) * | 2001-09-19 | 2011-07-19 | Neuronova Ab | Treatment of Parkinson's disease with PDGF |
| EP2314614B1 (en) | 2005-02-28 | 2015-11-25 | Sangamo BioSciences, Inc. | Anti-angiogenic methods and compositions |
| CN100448892C (zh) * | 2006-08-02 | 2009-01-07 | 中国人民解放军军事医学科学院基础医学研究所 | 抗肿瘤血管内皮生长因子受体vegf－r2抗原及其编码基因与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5073492A (en) * | 1987-01-09 | 1991-12-17 | The Johns Hopkins University | Synergistic composition for endothelial cell growth |
| US5332671A (en) * | 1989-05-12 | 1994-07-26 | Genetech, Inc. | Production of vascular endothelial cell growth factor and DNA encoding same |
| US5219739A (en) * | 1989-07-27 | 1993-06-15 | Scios Nova Inc. | DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121 |
| US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
| US5338671A (en) * | 1992-10-07 | 1994-08-16 | Eastman Kodak Company | DNA amplification with thermostable DNA polymerase and polymerase inhibiting antibody |
| JPH09510093A (ja) * | 1994-03-08 | 1997-10-14 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | 血管内皮細胞増殖因子２ |
| US5928939A (en) * | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
| US5607918A (en) * | 1995-03-01 | 1997-03-04 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-B and DNA coding therefor |
-
1996
- 1996-02-22 CN CNB961930357A patent/CN1194090C/zh not_active Expired - Lifetime
- 1996-02-22 AT AT96902810T patent/ATE252600T1/de active
- 1996-02-22 ES ES96902810T patent/ES2206558T3/es not_active Expired - Lifetime
- 1996-02-22 HU HU9800377A patent/HU223438B1/hu active IP Right Grant
- 1996-02-22 KR KR1019970706109A patent/KR100414615B1/ko not_active IP Right Cessation
- 1996-02-22 NZ NZ337634A patent/NZ337634A/en not_active IP Right Cessation
- 1996-02-22 WO PCT/AU1996/000094 patent/WO1996027007A1/en active IP Right Grant
- 1996-02-22 NZ NZ301611A patent/NZ301611A/en not_active IP Right Cessation
- 1996-02-22 BR BR9607628-3A patent/BR9607628A/pt not_active Application Discontinuation
- 1996-02-22 DE DE69630442T patent/DE69630442T2/de not_active Expired - Lifetime
- 1996-02-22 JP JP8525903A patent/JPH11500139A/ja not_active Withdrawn
- 1996-02-22 CA CA002214439A patent/CA2214439C/en not_active Expired - Lifetime
- 1996-02-22 EP EP96902810A patent/EP0815221B1/en not_active Expired - Lifetime
-
1997
- 1997-09-01 FI FI973571A patent/FI120153B/fi not_active IP Right Cessation
- 1997-09-02 NO NO19974035A patent/NO320839B1/no not_active IP Right Cessation
-
1998
- 1998-03-13 HK HK98102112A patent/HK1002963A1/xx not_active IP Right Cessation
-
2000
- 2000-06-14 JP JP2000178462A patent/JP3683778B2/ja not_active Expired - Lifetime
-
2006
- 2006-11-20 US US11/602,055 patent/US20070135344A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69630442D1 (de) | 2003-11-27 |
| EP0815221A4 (en) | 1998-12-09 |
| CA2214439A1 (en) | 1996-09-06 |
| ATE252600T1 (de) | 2003-11-15 |
| HU223438B1 (hu) | 2004-07-28 |
| NZ301611A (en) | 2000-02-28 |
| CN1194090C (zh) | 2005-03-23 |
| EP0815221A1 (en) | 1998-01-07 |
| US20070135344A1 (en) | 2007-06-14 |
| ES2206558T3 (es) | 2004-05-16 |
| NO974035L (no) | 1997-11-03 |
| JP3683778B2 (ja) | 2005-08-17 |
| EP0815221B1 (en) | 2003-10-22 |
| FI973571A (fi) | 1997-10-30 |
| HK1002963A1 (en) | 1998-09-30 |
| JP2001037493A (ja) | 2001-02-13 |
| NZ337634A (en) | 2001-06-29 |
| KR19980702702A (ko) | 1998-08-05 |
| WO1996027007A1 (en) | 1996-09-06 |
| HUP9800377A3 (en) | 2000-12-28 |
| BR9607628A (pt) | 1999-11-30 |
| JPH11500139A (ja) | 1999-01-06 |
| FI120153B (fi) | 2009-07-15 |
| CA2214439C (en) | 2002-12-17 |
| HUP9800377A1 (hu) | 1998-06-29 |
| DE69630442T2 (de) | 2004-08-19 |
| CN1224464A (zh) | 1999-07-28 |
| KR100414615B1 (ko) | 2004-05-27 |
| FI973571A0 (fi) | 1997-09-01 |
| NO974035D0 (no) | 1997-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |