NO318587B1 - Anvendelse av en CD40-reseptorbinder for fremstilling av et medikament for forebyggelse av epitelcelleproliferasjon eller for behandling av karsinomer i epitelcellesystemer, samt for forsterkning av mottakeligheten til neoplastiske epitelceller for anti-neoplastisk medikamentindusert apotose - Google Patents

Anvendelse av en CD40-reseptorbinder for fremstilling av et medikament for forebyggelse av epitelcelleproliferasjon eller for behandling av karsinomer i epitelcellesystemer, samt for forsterkning av mottakeligheten til neoplastiske epitelceller for anti-neoplastisk medikamentindusert apotose Download PDF

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Publication number
NO318587B1
NO318587B1 NO19972732A NO972732A NO318587B1 NO 318587 B1 NO318587 B1 NO 318587B1 NO 19972732 A NO19972732 A NO 19972732A NO 972732 A NO972732 A NO 972732A NO 318587 B1 NO318587 B1 NO 318587B1
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NO
Norway
Prior art keywords
drug
neoplastic
epithelial cell
treatment
epithelial
Prior art date
Application number
NO19972732A
Other languages
English (en)
Norwegian (no)
Other versions
NO972732D0 (no
NO972732L (no
Inventor
Lawrence Sterling Young
Original Assignee
Univ Birmingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Birmingham filed Critical Univ Birmingham
Publication of NO972732D0 publication Critical patent/NO972732D0/no
Publication of NO972732L publication Critical patent/NO972732L/no
Publication of NO318587B1 publication Critical patent/NO318587B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
NO19972732A 1994-12-13 1997-06-13 Anvendelse av en CD40-reseptorbinder for fremstilling av et medikament for forebyggelse av epitelcelleproliferasjon eller for behandling av karsinomer i epitelcellesystemer, samt for forsterkning av mottakeligheten til neoplastiske epitelceller for anti-neoplastisk medikamentindusert apotose NO318587B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9425060.2A GB9425060D0 (en) 1994-12-13 1994-12-13 Carcinoma treatment
PCT/GB1995/002807 WO1996018413A1 (en) 1994-12-13 1995-12-01 Carcinoma treatment

Publications (3)

Publication Number Publication Date
NO972732D0 NO972732D0 (no) 1997-06-13
NO972732L NO972732L (no) 1997-06-13
NO318587B1 true NO318587B1 (no) 2005-04-11

Family

ID=10765814

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19972732A NO318587B1 (no) 1994-12-13 1997-06-13 Anvendelse av en CD40-reseptorbinder for fremstilling av et medikament for forebyggelse av epitelcelleproliferasjon eller for behandling av karsinomer i epitelcellesystemer, samt for forsterkning av mottakeligheten til neoplastiske epitelceller for anti-neoplastisk medikamentindusert apotose

Country Status (12)

Country Link
EP (1) EP0806963B1 (de)
JP (1) JP4076230B2 (de)
AT (1) ATE203676T1 (de)
AU (1) AU691996B2 (de)
CA (1) CA2207779C (de)
DE (1) DE69522012T2 (de)
FI (1) FI118918B (de)
GB (1) GB9425060D0 (de)
MX (1) MX9704372A (de)
NO (1) NO318587B1 (de)
NZ (1) NZ296161A (de)
WO (1) WO1996018413A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ278740A (en) * 1993-12-23 1998-05-27 Immunex Corp Treating disease characterised by neoplastic cells expressing cd40 using a cd40 binding protein
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
HU228180B1 (hu) * 1998-08-11 2013-01-28 Biogen Idec Inc Anti-CD20-ellenanyag alkalmazása B-sejtes limfómák kombinációs terápiájára
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
US8557244B1 (en) 1999-08-11 2013-10-15 Biogen Idec Inc. Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody
US7138379B2 (en) * 2000-07-26 2006-11-21 Schering Aktiengesellschaft Use of the interferon receptor 2c polypeptide chain to enhance the anti-growth effects of type I interferons
GB0025132D0 (en) * 2000-10-13 2000-11-29 Medical Res Council Method
AR039067A1 (es) 2001-11-09 2005-02-09 Pfizer Prod Inc Anticuerpos para cd40
US7786282B2 (en) 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US7495090B2 (en) 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
US8277810B2 (en) 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
PT1680141E (pt) * 2003-11-04 2010-12-20 Novartis Vaccines & Diagnostic Métodos terapêuticos para tumores sólidos que expressam o antigénio de superfície celular cd40
US20050136055A1 (en) 2003-12-22 2005-06-23 Pfizer Inc CD40 antibody formulation and methods
ES2354865T3 (es) 2005-05-26 2011-03-18 Seattle Genetics, Inc. Anticuerpos anti-cd40 humanizados y métodos para utilizarlos.
WO2007053767A1 (en) 2005-11-01 2007-05-10 Novartis Ag Uses of anti-cd40 antibodies
US9005974B2 (en) 2005-12-09 2015-04-14 Academish Medisch Centrum Bij De Universiteit Van Amsterdam Means and methods for influencing the stability of cells
JP5753339B2 (ja) 2005-12-09 2015-07-22 アカデミッシュ メディッシュ セントラム ビーアイジェイ ド ユニバーシテイト バン アムステルダム 抗体産生細胞の安定性に影響を与える手段および方法
NZ571757A (en) 2006-04-21 2012-01-12 Novartis Ag Antagonist anti-CD40 antibody pharmaceutical compositions comprising arginine-HCl and a citrate or citric acid buffer
CA2704499C (en) 2007-11-07 2020-03-10 Genentech, Inc. Methods and compositions for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies
BRPI1011394A8 (pt) 2009-04-18 2018-06-26 Genentech Inc método para avaliação de responsividade de linforma de células b ao tratamento com anticorpos anti-cd40
DK2454283T3 (en) 2009-07-15 2018-05-07 Aimm Therapeutics Bv METHODS AND PROCEDURES FOR MANUFACTURING HIGH EFFICIENCY ANTIBODIES
AR083847A1 (es) 2010-11-15 2013-03-27 Novartis Ag Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40
PT2646466T (pt) 2010-12-02 2017-06-07 Aimm Therapeutics Bv Meios e métodos para produzir anticorpos de alta afinidade
SG194701A1 (en) 2011-04-29 2013-12-30 Apexigen Inc Anti-cd40 antibodies and methods of use
ES2879552T3 (es) 2012-10-30 2021-11-22 Apexigen Inc Anticuerpos anti-CD40 y métodos de uso
JP6747975B2 (ja) 2014-01-31 2020-08-26 アイム・セラピューティクス・べー・フェー 安定な抗体を産生するための手段及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation

Also Published As

Publication number Publication date
AU691996B2 (en) 1998-05-28
JPH10510526A (ja) 1998-10-13
WO1996018413A1 (en) 1996-06-20
FI972484A0 (fi) 1997-06-12
ATE203676T1 (de) 2001-08-15
JP4076230B2 (ja) 2008-04-16
CA2207779A1 (en) 1996-06-20
FI118918B (fi) 2008-05-15
EP0806963A1 (de) 1997-11-19
GB9425060D0 (en) 1995-02-08
AU3988495A (en) 1996-07-03
NO972732D0 (no) 1997-06-13
DE69522012D1 (de) 2001-09-06
EP0806963B1 (de) 2001-08-01
CA2207779C (en) 2009-10-06
FI972484A (fi) 1997-06-12
NO972732L (no) 1997-06-13
DE69522012T2 (de) 2002-04-25
MX9704372A (es) 1998-02-28
NZ296161A (en) 2001-10-26

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