DE69522012T2 - Karzinombehandlung - Google Patents
KarzinombehandlungInfo
- Publication number
- DE69522012T2 DE69522012T2 DE69522012T DE69522012T DE69522012T2 DE 69522012 T2 DE69522012 T2 DE 69522012T2 DE 69522012 T DE69522012 T DE 69522012T DE 69522012 T DE69522012 T DE 69522012T DE 69522012 T2 DE69522012 T2 DE 69522012T2
- Authority
- DE
- Germany
- Prior art keywords
- cancer treatment
- treatment
- carcinomas
- inducer
- prevention
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9425060.2A GB9425060D0 (en) | 1994-12-13 | 1994-12-13 | Carcinoma treatment |
PCT/GB1995/002807 WO1996018413A1 (en) | 1994-12-13 | 1995-12-01 | Carcinoma treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69522012D1 DE69522012D1 (de) | 2001-09-06 |
DE69522012T2 true DE69522012T2 (de) | 2002-04-25 |
Family
ID=10765814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69522012T Expired - Lifetime DE69522012T2 (de) | 1994-12-13 | 1995-12-01 | Karzinombehandlung |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0806963B1 (de) |
JP (1) | JP4076230B2 (de) |
AT (1) | ATE203676T1 (de) |
AU (1) | AU691996B2 (de) |
CA (1) | CA2207779C (de) |
DE (1) | DE69522012T2 (de) |
FI (1) | FI118918B (de) |
GB (1) | GB9425060D0 (de) |
MX (1) | MX9704372A (de) |
NO (1) | NO318587B1 (de) |
NZ (1) | NZ296161A (de) |
WO (1) | WO1996018413A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09507074A (ja) * | 1993-12-23 | 1997-07-15 | イミュネックス・コーポレーション | Cd40を発現する腫瘍細胞を特徴とする疾患の予防又は治療方法 |
US7070771B1 (en) | 1996-12-09 | 2006-07-04 | Regents Of The University Of California | Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells |
EA004107B1 (ru) | 1998-08-11 | 2003-12-25 | Айдек Фармацевтикалс Корпорэйшн | Комбинированная терапия в-клеточных лимфом, предусматривающая введение антитела против cd20 |
US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
US8557244B1 (en) | 1999-08-11 | 2013-10-15 | Biogen Idec Inc. | Treatment of aggressive non-Hodgkins lymphoma with anti-CD20 antibody |
US7138379B2 (en) * | 2000-07-26 | 2006-11-21 | Schering Aktiengesellschaft | Use of the interferon receptor 2c polypeptide chain to enhance the anti-growth effects of type I interferons |
GB0025132D0 (en) * | 2000-10-13 | 2000-11-29 | Medical Res Council | Method |
AR039067A1 (es) * | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
US7786282B2 (en) | 2001-12-06 | 2010-08-31 | The Regents Of The University Of California | Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain |
US7495090B2 (en) | 2002-05-23 | 2009-02-24 | The Regents Of The University Of California | Nucleic acids encoding chimeric CD154 polypeptides |
US8277810B2 (en) | 2003-11-04 | 2012-10-02 | Novartis Vaccines & Diagnostics, Inc. | Antagonist anti-CD40 antibodies |
CA2544852A1 (en) * | 2003-11-04 | 2005-05-19 | Chiron Corporation | Methods of therapy for solid tumors expressing the cd40 cell-surface antigen |
US20050136055A1 (en) | 2003-12-22 | 2005-06-23 | Pfizer Inc | CD40 antibody formulation and methods |
CA2609269C (en) | 2005-05-26 | 2014-08-05 | Seattle Genetics, Inc. | Humanized anti-cd40 antibodies and their methods of use |
KR20080073725A (ko) | 2005-11-01 | 2008-08-11 | 노파르티스 아게 | 항-cd40 항체의 용도 |
PT2540820T (pt) | 2005-12-09 | 2018-03-02 | Academisch Medisch Centrum Bij De Univ Van Amsterdam | Meios e métodos para influenciar a establidade de células produtoras de anticorpos |
WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
WO2007124299A2 (en) | 2006-04-21 | 2007-11-01 | Novartis Ag | Antagonist anti-cd40 antibody pharmaceutical compositions |
MX2010005080A (es) | 2007-11-07 | 2010-07-28 | Genentech Inc | Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. |
CN102459639A (zh) | 2009-04-18 | 2012-05-16 | 健泰科生物技术公司 | 用于评估b细胞淋巴瘤对抗cd40抗体治疗的响应性的方法 |
JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
CN103429615B (zh) | 2010-12-02 | 2018-03-16 | 埃姆医疗有限公司 | 用于生产高亲和力抗体的方式和方法 |
JP6125489B2 (ja) | 2011-04-29 | 2017-05-10 | アペクシジェン, インコーポレイテッド | 抗cd40抗体および使用方法 |
AU2013337903B2 (en) | 2012-10-30 | 2018-08-16 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
EP3099709B1 (de) | 2014-01-31 | 2019-12-25 | AIMM Therapeutics B.V. | Mittel und verfahren zur herstellung von stabilen antikörpern |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5540926A (en) * | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
-
1994
- 1994-12-13 GB GBGB9425060.2A patent/GB9425060D0/en active Pending
-
1995
- 1995-12-01 JP JP51844696A patent/JP4076230B2/ja not_active Expired - Fee Related
- 1995-12-01 CA CA002207779A patent/CA2207779C/en not_active Expired - Fee Related
- 1995-12-01 NZ NZ296161A patent/NZ296161A/en not_active IP Right Cessation
- 1995-12-01 AU AU39884/95A patent/AU691996B2/en not_active Ceased
- 1995-12-01 EP EP95938518A patent/EP0806963B1/de not_active Expired - Lifetime
- 1995-12-01 WO PCT/GB1995/002807 patent/WO1996018413A1/en active IP Right Grant
- 1995-12-01 AT AT95938518T patent/ATE203676T1/de active
- 1995-12-01 DE DE69522012T patent/DE69522012T2/de not_active Expired - Lifetime
- 1995-12-01 MX MX9704372A patent/MX9704372A/es not_active IP Right Cessation
-
1997
- 1997-06-12 FI FI972484A patent/FI118918B/fi active IP Right Grant
- 1997-06-13 NO NO19972732A patent/NO318587B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2207779A1 (en) | 1996-06-20 |
JPH10510526A (ja) | 1998-10-13 |
FI118918B (fi) | 2008-05-15 |
CA2207779C (en) | 2009-10-06 |
ATE203676T1 (de) | 2001-08-15 |
NO972732D0 (no) | 1997-06-13 |
MX9704372A (es) | 1998-02-28 |
WO1996018413A1 (en) | 1996-06-20 |
AU691996B2 (en) | 1998-05-28 |
NO318587B1 (no) | 2005-04-11 |
EP0806963B1 (de) | 2001-08-01 |
DE69522012D1 (de) | 2001-09-06 |
GB9425060D0 (en) | 1995-02-08 |
AU3988495A (en) | 1996-07-03 |
FI972484A0 (fi) | 1997-06-12 |
NZ296161A (en) | 2001-10-26 |
FI972484A (fi) | 1997-06-12 |
EP0806963A1 (de) | 1997-11-19 |
JP4076230B2 (ja) | 2008-04-16 |
NO972732L (no) | 1997-06-13 |
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