NO315651B1 - Benzopyraner, farmasöytiske preparater inneholdende disse og deres anvendelse som terapeutiske midler - Google Patents

Benzopyraner, farmasöytiske preparater inneholdende disse og deres anvendelse som terapeutiske midler Download PDF

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Publication number
NO315651B1
NO315651B1 NO19965260A NO965260A NO315651B1 NO 315651 B1 NO315651 B1 NO 315651B1 NO 19965260 A NO19965260 A NO 19965260A NO 965260 A NO965260 A NO 965260A NO 315651 B1 NO315651 B1 NO 315651B1
Authority
NO
Norway
Prior art keywords
acetyl
benzopyran
dimethyl
dihydro
pharmaceutically acceptable
Prior art date
Application number
NO19965260A
Other languages
English (en)
Norwegian (no)
Other versions
NO965260L (no
NO965260D0 (no
Inventor
Wai Ngor Chan
Helen Kate Ann Morgan
Mervyn Thompson
John Morris Evans
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9411632A external-priority patent/GB9411632D0/en
Priority claimed from GB9411798A external-priority patent/GB9411798D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO965260D0 publication Critical patent/NO965260D0/no
Publication of NO965260L publication Critical patent/NO965260L/no
Publication of NO315651B1 publication Critical patent/NO315651B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
NO19965260A 1994-06-10 1996-12-09 Benzopyraner, farmasöytiske preparater inneholdende disse og deres anvendelse som terapeutiske midler NO315651B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9411632A GB9411632D0 (en) 1994-06-10 1994-06-10 Novel treatment
GB9411798A GB9411798D0 (en) 1994-06-13 1994-06-13 Novel treatment
PCT/EP1995/002076 WO1995034545A1 (en) 1994-06-10 1995-05-31 Benzopyrans and their use as therapeutic agents

Publications (3)

Publication Number Publication Date
NO965260D0 NO965260D0 (no) 1996-12-09
NO965260L NO965260L (no) 1997-02-06
NO315651B1 true NO315651B1 (no) 2003-10-06

Family

ID=26305044

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19965260A NO315651B1 (no) 1994-06-10 1996-12-09 Benzopyraner, farmasöytiske preparater inneholdende disse og deres anvendelse som terapeutiske midler

Country Status (29)

Country Link
US (1) US5760074A (pt)
EP (2) EP0764157B1 (pt)
JP (2) JP3575767B2 (pt)
KR (1) KR100397721B1 (pt)
CN (2) CN1174975C (pt)
AP (1) AP714A (pt)
AT (2) ATE250052T1 (pt)
AU (1) AU701060B2 (pt)
BG (1) BG63339B1 (pt)
BR (1) BR9507980A (pt)
CA (1) CA2192480C (pt)
CY (1) CY2508B1 (pt)
CZ (1) CZ286081B6 (pt)
DE (2) DE69524871T2 (pt)
DK (2) DK1114821T3 (pt)
ES (2) ES2207590T3 (pt)
FI (1) FI120686B (pt)
HK (2) HK1001286A1 (pt)
HU (1) HUT76136A (pt)
NO (1) NO315651B1 (pt)
NZ (1) NZ287872A (pt)
OA (1) OA10593A (pt)
PL (1) PL188134B1 (pt)
PT (2) PT764157E (pt)
RO (1) RO113463B1 (pt)
SG (1) SG67930A1 (pt)
SI (2) SI0764157T1 (pt)
SK (1) SK281456B6 (pt)
WO (1) WO1995034545A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010021780A1 (en) * 1992-12-11 2001-09-13 Smithkline Beecham P.L.C. Pharmaceutical composition containing bicyclic type compounds
GB9411635D0 (en) * 1994-06-10 1994-08-03 Smithkline Beecham Plc Novel treatment
US6492415B2 (en) * 1996-09-18 2002-12-10 Smithkline Beecham P.L.C. Use of benzopyranols to treat neurological disorders
GB9619492D0 (en) * 1996-09-18 1996-10-30 Smithkline Beecham Plc Novel treatment
GB9726543D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel compositions
GB9813949D0 (en) * 1998-06-29 1998-08-26 Smithkline Beecham Plc Novel compounds
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
WO2006107019A1 (ja) * 2005-04-04 2006-10-12 Takeda Pharmaceutical Company Limited うつ病または不安神経症の予防または治療剤
WO2009147441A2 (en) * 2008-06-05 2009-12-10 Minster Research Limited Novel treatments
US20130281524A1 (en) * 2008-06-05 2013-10-24 Peter Blower Novel treatments
WO2011067608A1 (en) 2009-12-03 2011-06-09 Minster Research Ltd Treatment of allodynia and hyperalgesia
CA2782631A1 (en) 2009-12-03 2011-06-09 Proximagen Ltd Treatment of infectious diseases
AU2013285164A1 (en) 2012-07-03 2015-01-22 Proximagen Limited Pro-drug compounds
GB201304814D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Pro-drug compounds
GB201322934D0 (en) 2013-12-23 2014-02-12 Proximagen Ltd Prodrug compounds
GB201322932D0 (en) * 2013-12-23 2014-02-12 Proximagen Ltd Pro-drug compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
GB9112721D0 (en) * 1991-06-13 1991-07-31 Smithkline Beecham Plc Novel treatment
EP0673373A1 (en) * 1992-12-11 1995-09-27 Smithkline Beecham Plc Bicyclic compounds with pharmaceutical activity
JP3568533B2 (ja) * 1992-12-11 2004-09-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 二環式化合物含有の医薬組成物
US5536718A (en) * 1995-01-17 1996-07-16 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists

Also Published As

Publication number Publication date
SK158796A3 (en) 1997-07-09
BG63339B1 (bg) 2001-10-31
JPH10501251A (ja) 1998-02-03
EP1114821A1 (en) 2001-07-11
DK0764157T3 (da) 2002-04-22
ES2207590T3 (es) 2004-06-01
NZ287872A (en) 1998-05-27
PT764157E (pt) 2002-06-28
EP0764157A1 (en) 1997-03-26
FI964936A (fi) 1997-02-06
CN1336369A (zh) 2002-02-20
DE69531801T2 (de) 2004-07-01
RO113463B1 (ro) 1998-07-30
CN1174975C (zh) 2004-11-10
CN1154698A (zh) 1997-07-16
EP0764157B1 (en) 2002-01-02
CA2192480C (en) 2007-07-24
CA2192480A1 (en) 1995-12-21
AP9600889A0 (en) 1997-01-31
HU9603415D0 (en) 1997-02-28
JP3575767B2 (ja) 2004-10-13
DE69531801D1 (de) 2003-10-23
SK281456B6 (sk) 2001-03-12
NO965260L (no) 1997-02-06
HUT76136A (en) 1997-06-30
CZ286081B6 (cs) 2000-01-12
CZ361796A3 (en) 1997-08-13
DE69524871T2 (de) 2002-08-22
KR100397721B1 (ko) 2004-04-28
AU701060B2 (en) 1999-01-21
US5760074A (en) 1998-06-02
AP714A (en) 1998-12-23
SI0764157T1 (en) 2002-06-30
FI120686B (fi) 2010-01-29
HK1039115A1 (en) 2002-04-12
DK1114821T3 (da) 2004-02-02
CY2508B1 (en) 2005-12-23
PL188134B1 (pl) 2004-12-31
WO1995034545A1 (en) 1995-12-21
PT1114821E (pt) 2004-02-27
SG67930A1 (en) 1999-10-19
HK1001286A1 (en) 1998-06-12
JP2003238554A (ja) 2003-08-27
FI964936A0 (fi) 1996-12-10
EP1114821B1 (en) 2003-09-17
SI1114821T1 (en) 2004-02-29
BG101040A (en) 1997-08-29
ATE211469T1 (de) 2002-01-15
DE69524871D1 (de) 2002-02-07
OA10593A (en) 2002-07-10
ES2170798T3 (es) 2002-08-16
CN1234702C (zh) 2006-01-04
PL317579A1 (en) 1997-04-14
HK1039115B (zh) 2004-08-13
ATE250052T1 (de) 2003-10-15
BR9507980A (pt) 1997-08-12
NO965260D0 (no) 1996-12-09
AU2672795A (en) 1996-01-05

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