NO315051B1 - Tumoravvisningsantigenforlöpere, tumoravvisningsantigener samt anvendelse derav - Google Patents
Tumoravvisningsantigenforlöpere, tumoravvisningsantigener samt anvendelse derav Download PDFInfo
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- NO315051B1 NO315051B1 NO19934130A NO934130A NO315051B1 NO 315051 B1 NO315051 B1 NO 315051B1 NO 19934130 A NO19934130 A NO 19934130A NO 934130 A NO934130 A NO 934130A NO 315051 B1 NO315051 B1 NO 315051B1
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- tumor rejection
- antigen
- cells
- nucleic acid
- rejection antigen
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70570291A | 1991-05-23 | 1991-05-23 | |
US72883891A | 1991-07-09 | 1991-07-09 | |
US07/764,364 US5327252A (en) | 1990-09-21 | 1991-09-23 | Print evaluation apparatus |
US07/807,043 US5342774A (en) | 1991-05-23 | 1991-12-12 | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
PCT/US1992/004354 WO1992020356A1 (en) | 1991-05-23 | 1992-05-22 | Tumor rejection antigen precursors, tumor rejection antigens and uses thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
NO934130D0 NO934130D0 (no) | 1993-11-16 |
NO934130L NO934130L (no) | 1993-11-23 |
NO315051B1 true NO315051B1 (no) | 2003-06-30 |
Family
ID=27505492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19934130A NO315051B1 (no) | 1991-05-23 | 1993-11-16 | Tumoravvisningsantigenforlöpere, tumoravvisningsantigener samt anvendelse derav |
Country Status (13)
Country | Link |
---|---|
US (1) | US5342774A (de) |
EP (1) | EP0595838B1 (de) |
JP (1) | JP3484459B2 (de) |
AT (1) | ATE279514T1 (de) |
CA (2) | CA2109727C (de) |
DE (1) | DE69233435T2 (de) |
DK (1) | DK0595838T3 (de) |
ES (1) | ES2225818T3 (de) |
FI (1) | FI117555B (de) |
IL (1) | IL101963A (de) |
NO (1) | NO315051B1 (de) |
PT (1) | PT100515B (de) |
WO (1) | WO1992020356A1 (de) |
Families Citing this family (178)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5541104A (en) * | 1991-05-23 | 1996-07-30 | Ludwig Institute For Cancer Research | Monoclonal antibodies which bind to tumor rejection antigen precursor mage-1 |
US5612201A (en) * | 1991-05-23 | 1997-03-18 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules useful in determining expression of a tumor rejection antigen precursor |
US5925729A (en) * | 1991-05-23 | 1999-07-20 | Ludwig Institute For Cancer Research | Tumor rejection antigen precursors, tumor rejection antigens and uses thereof |
US6235525B1 (en) * | 1991-05-23 | 2001-05-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof |
US7252829B1 (en) * | 1998-06-17 | 2007-08-07 | Idm Pharma, Inc. | HLA binding peptides and their uses |
US5662907A (en) * | 1992-08-07 | 1997-09-02 | Cytel Corporation | Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes |
WO1994005304A1 (en) * | 1992-08-31 | 1994-03-17 | Ludwig Institute For Cancer Research | Isolated nonapeptide derived from mage-3 gene and presented by hla-a1, and uses thereof |
US5462871A (en) * | 1992-08-31 | 1995-10-31 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which encode MAGE derived nonapeptides |
US6222012B1 (en) | 1992-08-31 | 2001-04-24 | Ludwig Institute For Cancer Research | Isolated nonapeptides presented by HLA molecules, and uses thereof |
US5405940A (en) * | 1992-08-31 | 1995-04-11 | Ludwig Institute For Cancer Research | Isolated nonapeptides derived from MAGE genes and uses thereof |
DE69331813T4 (de) | 1992-12-22 | 2003-07-10 | Ludwig Inst Cancer Res | Verfahren zur Detektion und Behandlung von Individuen mit abnormal hla-a2/tyrosinase-peptidantigenen exprimierenden Zellen |
CA2154468A1 (en) * | 1993-01-22 | 1994-08-04 | Pierre Van Der Bruggen | Method for identifying and treating individuals bearing cancer cells that express hla-c-clone 10/mage-1 |
US6328971B1 (en) * | 1993-01-22 | 2001-12-11 | Ludwig Institute For Cancer Research | MAGE-1 derived nona peptides, and compositions thereof |
US5558995A (en) * | 1993-01-22 | 1996-09-24 | Ludwig Institute For Cancer Research | Peptides which are derived from tumor rejection antigen precursor molecule MAGE-1, which complex to MHC molecule HLA-C clone 10, and uses thereof |
US5620886A (en) * | 1993-03-18 | 1997-04-15 | Ludwig Institute For Cancer Research | Isolated nucleic acid sequence coding for a tumor rejection antigen precursor processed to at least one tumor rejection antigen presented by HLA-A2 |
US5877017A (en) * | 1993-06-17 | 1999-03-02 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecule encoding peptides which form complexes with MHC molecule HLA-Cw*1601 and uses thereof |
US5571711A (en) * | 1993-06-17 | 1996-11-05 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for BAGE tumor rejection antigen precursors |
US5610013A (en) * | 1993-07-22 | 1997-03-11 | Ludwig Institute For Cancer Research | Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors |
AU702517B2 (en) * | 1993-08-06 | 1999-02-25 | Epimmune, Inc. | Cloning and characterization of the complete MAGE-1 gene |
US6652850B1 (en) | 1993-09-13 | 2003-11-25 | Aventis Pharmaceuticals Inc. | Adeno-associated viral liposomes and their use in transfecting dendritic cells to stimulate specific immunity |
FR2710536B1 (fr) * | 1993-09-29 | 1995-12-22 | Transgene Sa | Usage anti-cancéreux d'un vecteur viral comportant un gène modulateur de la réponse immunitaire et/ou inflammatoire. |
DE69533295T3 (de) * | 1994-02-16 | 2009-07-16 | The Government Of The United States Of America, As Represented By The Secretary, The Department Of Health And Human Services | Melanoma-assoziierte Antigene, Epitope davon und Impstoffe gegen Melanoma |
DE69524264T2 (de) * | 1994-03-01 | 2002-07-18 | Ludwig Inst Cancer Res | Bestimmung krebsartiger beschaffenheiten durch die genexpression eines mitgliedes der melanomartigengruppe, mage |
US5512437A (en) * | 1994-03-01 | 1996-04-30 | Ludwig Institute For Cancer Research | Method for determining head and neck squamous cell carcinomas, prostate carcinomas, and bladder tumors by assaying for mage-3 |
US5763165A (en) * | 1994-03-10 | 1998-06-09 | Ludwig Institute For Cancer Research | Method for determining lung adenocarcinomas by assaying for one or more of MAGE-1, MAGE-2 and MAGE-3 |
US5512444A (en) * | 1994-03-01 | 1996-04-30 | Ludwig Institute For Cancer Research | Method for determining bladder tumors by assaying for MAGE-1,2,3 or 4 |
US5585461A (en) * | 1994-03-24 | 1996-12-17 | Ludwig Institute For Cancer Research | Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof |
US5686068A (en) * | 1994-03-24 | 1997-11-11 | Ludwig Institute For Cancer Research | Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof |
US5554506A (en) * | 1994-03-24 | 1996-09-10 | Ludwig Institute For Cancer Research | Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof |
US5554724A (en) * | 1994-03-24 | 1996-09-10 | University Of Leiden | Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof |
US5851523A (en) * | 1994-03-24 | 1998-12-22 | Ludwig Institute For Cancer Research. | Isolated, peptides derived from MAGE tumor rejection antigen precursors which complex with HLA-A2 molecules and uses thereof |
JPH10505481A (ja) | 1994-04-22 | 1998-06-02 | アメリカ合衆国 | メラノーマ抗原 |
US5874560A (en) | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
US5589334A (en) * | 1994-06-03 | 1996-12-31 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecule which codes for a tumor rejection antigen precursor which is processed to an antigen presented by HLA-B44, and uses thereof |
US5977300A (en) * | 1994-06-03 | 1999-11-02 | Ludwig Institute Of Cancer Research | Isolated nonapeptide which bind to HLA-B44 molecules and the uses thereof |
US6060257A (en) * | 1994-06-03 | 2000-05-09 | Ludwig Institute For Cancer Research | Tumor rejection antigens presented by HLA-B44 molecules, and uses thereof |
US5997870A (en) | 1994-06-03 | 1999-12-07 | Ludwig Institute For Cancer Research | Isolated peptides which bind to HLA-B44 Molecules |
US5834245A (en) * | 1994-07-29 | 1998-11-10 | Cancer Institute | PRLTS proteins and DNA's encoding the same |
CA2201327A1 (en) * | 1994-09-30 | 1996-04-11 | Ludwig Institute For Cancer Research | Compositions containing tumor rejection antigen precursors or tumor rejection antigens, and an adjuvant and/or growth factor |
US5830753A (en) * | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
DE69519521T2 (de) | 1994-10-03 | 2001-06-28 | Us Gov Nat Inst Health | Zusammensetzung enthaltend ein antigen exprimierendes rekombinantes virus und ein immunstimulierendes molekül exprimierendes rekombinantes virus |
US7635479B2 (en) * | 2000-03-29 | 2009-12-22 | The Trustees Of The University Of Pennsylvania | Composition and methods for enhancing immunogenecity of antigens |
US8114414B2 (en) * | 1994-11-08 | 2012-02-14 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical cancer |
US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
US20070264279A1 (en) * | 1994-11-08 | 2007-11-15 | Claudia Gravekamp | Compositions and methods comprising a MAGE-b antigen |
US6051237A (en) * | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
US8791237B2 (en) * | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
US8956621B2 (en) | 1994-11-08 | 2015-02-17 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of cervical dysplasia |
US7662396B2 (en) * | 2001-03-26 | 2010-02-16 | The Trustees Of The University Of Pennsylvania | Compositions and methods for enhancing the immunogenicity of antigens |
US7820180B2 (en) * | 2004-09-24 | 2010-10-26 | The Trustees Of The University Of Pennsylvania | Listeria-based and LLO-based vaccines |
US5843648A (en) * | 1995-01-10 | 1998-12-01 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | P15 and tyrosinase melanoma antigens and their use in diagnostic and therapeutic methods |
US5587289A (en) * | 1995-03-14 | 1996-12-24 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which are members of the MAGE-Xp family and uses thereof |
US6017705A (en) * | 1995-03-14 | 2000-01-25 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules which are members of the MAGE-B family and uses thereof |
US5759783A (en) * | 1995-03-14 | 1998-06-02 | Ludwig Institute For Cancer Research | Method of screening for cancer by detecting messenger RNA for a MAGE-XP gene |
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US5141742A (en) * | 1986-02-07 | 1992-08-25 | Oncogen | Vaccines against melanoma |
US5185432A (en) * | 1986-02-26 | 1993-02-09 | Oncogen | Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas |
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US5188959A (en) * | 1989-09-28 | 1993-02-23 | Trustees Of Tufts College | Extracellular matrix protein adherent t cells |
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CA2307317A1 (en) | 1992-11-26 |
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NO934130D0 (no) | 1993-11-16 |
IL101963A (en) | 2004-03-28 |
CA2109727C (en) | 2000-07-25 |
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ATE279514T1 (de) | 2004-10-15 |
EP0595838B1 (de) | 2004-10-13 |
NO934130L (no) | 1993-11-23 |
JPH06511144A (ja) | 1994-12-15 |
ES2225818T3 (es) | 2005-03-16 |
FI117555B (fi) | 2006-11-30 |
PT100515A (pt) | 1993-08-31 |
EP0595838A4 (en) | 1995-10-25 |
DE69233435T2 (de) | 2005-03-03 |
FI935174A (fi) | 1993-11-22 |
WO1992020356A1 (en) | 1992-11-26 |
FI935174A0 (fi) | 1993-11-22 |
JP3484459B2 (ja) | 2004-01-06 |
DK0595838T3 (da) | 2005-01-31 |
EP0595838A1 (de) | 1994-05-11 |
US5342774A (en) | 1994-08-30 |
CA2109727A1 (en) | 1992-11-26 |
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