PT100515A - Moleculas de acido nucleico, precursores de antigenios de rejeicao de tumores, antigenios da rejeicao de tumores e suas utilizacoes - Google Patents

Moleculas de acido nucleico, precursores de antigenios de rejeicao de tumores, antigenios da rejeicao de tumores e suas utilizacoes

Info

Publication number
PT100515A
PT100515A PT100515A PT10051592A PT100515A PT 100515 A PT100515 A PT 100515A PT 100515 A PT100515 A PT 100515A PT 10051592 A PT10051592 A PT 10051592A PT 100515 A PT100515 A PT 100515A
Authority
PT
Portugal
Prior art keywords
tumor rejection
rejection antigens
precursors
nucleic acid
acid molecules
Prior art date
Application number
PT100515A
Other languages
English (en)
Other versions
PT100515B (pt
Inventor
Thierry Boon
Pierre Van Der Bruggen
Benoit Van Den Eynde
Aline Van Pel
Etienne De Plaen
Christophe Lurquin
Patrick Chomez
Catia Traversari
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/764,364 external-priority patent/US5327252A/en
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Publication of PT100515A publication Critical patent/PT100515A/pt
Publication of PT100515B publication Critical patent/PT100515B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT100515A 1991-05-23 1992-05-22 Moleculas de acido nucleico, precursores de antigenios de rejeicao de tumores, antigenios da rejeicao de tumores e suas utilizacoes PT100515B (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70570291A 1991-05-23 1991-05-23
US72883891A 1991-07-09 1991-07-09
US07/764,364 US5327252A (en) 1990-09-21 1991-09-23 Print evaluation apparatus
US07/807,043 US5342774A (en) 1991-05-23 1991-12-12 Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1

Publications (2)

Publication Number Publication Date
PT100515A true PT100515A (pt) 1993-08-31
PT100515B PT100515B (pt) 1999-08-31

Family

ID=27505492

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100515A PT100515B (pt) 1991-05-23 1992-05-22 Moleculas de acido nucleico, precursores de antigenios de rejeicao de tumores, antigenios da rejeicao de tumores e suas utilizacoes

Country Status (13)

Country Link
US (1) US5342774A (pt)
EP (1) EP0595838B1 (pt)
JP (1) JP3484459B2 (pt)
AT (1) ATE279514T1 (pt)
CA (2) CA2307317C (pt)
DE (1) DE69233435T2 (pt)
DK (1) DK0595838T3 (pt)
ES (1) ES2225818T3 (pt)
FI (1) FI117555B (pt)
IL (1) IL101963A (pt)
NO (1) NO315051B1 (pt)
PT (1) PT100515B (pt)
WO (1) WO1992020356A1 (pt)

Families Citing this family (179)

* Cited by examiner, † Cited by third party
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US5405940A (en) * 1992-08-31 1995-04-11 Ludwig Institute For Cancer Research Isolated nonapeptides derived from MAGE genes and uses thereof
US6222012B1 (en) 1992-08-31 2001-04-24 Ludwig Institute For Cancer Research Isolated nonapeptides presented by HLA molecules, and uses thereof
US5462871A (en) * 1992-08-31 1995-10-31 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode MAGE derived nonapeptides
ATE197403T1 (de) 1992-12-22 2000-11-11 Ludwig Inst Cancer Res Methoden zur detektion und behandlung von individuen mit abnormalen hla-a2/tyrosinase- peptidantigenen exprimierenden zellen
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US5585461A (en) * 1994-03-24 1996-12-17 Ludwig Institute For Cancer Research Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
US5686068A (en) * 1994-03-24 1997-11-11 Ludwig Institute For Cancer Research Isolated peptides derived from MAGE-2, cytolytic T cells specific to complexes of peptide and HLA-A2 molecules, and uses thereof
US5554506A (en) * 1994-03-24 1996-09-10 Ludwig Institute For Cancer Research Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
US5554724A (en) * 1994-03-24 1996-09-10 University Of Leiden Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof
US5874560A (en) 1994-04-22 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Melanoma antigens and their use in diagnostic and therapeutic methods
EP1630229B1 (en) * 1994-04-22 2013-04-03 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Melanoma antigens
US6060257A (en) * 1994-06-03 2000-05-09 Ludwig Institute For Cancer Research Tumor rejection antigens presented by HLA-B44 molecules, and uses thereof
US5997870A (en) * 1994-06-03 1999-12-07 Ludwig Institute For Cancer Research Isolated peptides which bind to HLA-B44 Molecules
US5589334A (en) * 1994-06-03 1996-12-31 Ludwig Institute For Cancer Research Isolated nucleic acid molecule which codes for a tumor rejection antigen precursor which is processed to an antigen presented by HLA-B44, and uses thereof
US5977300A (en) * 1994-06-03 1999-11-02 Ludwig Institute Of Cancer Research Isolated nonapeptide which bind to HLA-B44 molecules and the uses thereof
US5834245A (en) * 1994-07-29 1998-11-10 Cancer Institute PRLTS proteins and DNA's encoding the same
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US5830753A (en) * 1994-09-30 1998-11-03 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof.
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CA2307317A1 (en) 1992-11-26
PT100515B (pt) 1999-08-31
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FI935174A0 (fi) 1993-11-22
IL101963A (en) 2004-03-28
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CA2109727C (en) 2000-07-25
ATE279514T1 (de) 2004-10-15
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FI935174A (fi) 1993-11-22
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CA2109727A1 (en) 1992-11-26
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JPH06511144A (ja) 1994-12-15
US5342774A (en) 1994-08-30

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