NO313755B1 - 2-imidazolinylaminobenzoksazolforbindelser anvendelige som <alfa>-2 adrenoceptoragonister - Google Patents

2-imidazolinylaminobenzoksazolforbindelser anvendelige som <alfa>-2 adrenoceptoragonister Download PDF

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Publication number
NO313755B1
NO313755B1 NO19992500A NO992500A NO313755B1 NO 313755 B1 NO313755 B1 NO 313755B1 NO 19992500 A NO19992500 A NO 19992500A NO 992500 A NO992500 A NO 992500A NO 313755 B1 NO313755 B1 NO 313755B1
Authority
NO
Norway
Prior art keywords
dosage range
compounds
alkanyl
unsubstituted
compound according
Prior art date
Application number
NO19992500A
Other languages
English (en)
Norwegian (no)
Other versions
NO992500D0 (no
NO992500L (no
Inventor
Raymond Todd Henry
Russell James Sheldon
William Lee Seibel
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO992500D0 publication Critical patent/NO992500D0/no
Publication of NO992500L publication Critical patent/NO992500L/no
Publication of NO313755B1 publication Critical patent/NO313755B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO19992500A 1996-11-25 1999-05-25 2-imidazolinylaminobenzoksazolforbindelser anvendelige som <alfa>-2 adrenoceptoragonister NO313755B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3178796P 1996-11-25 1996-11-25
PCT/US1997/020803 WO1998023611A1 (fr) 1996-11-25 1997-11-21 COMPOSES 2-IMIDAZOLINYLAMINOBENZOXAZOLE CONVENANT COMME AGONISTES DE L'ADRENORECEPTEUR α-2

Publications (3)

Publication Number Publication Date
NO992500D0 NO992500D0 (no) 1999-05-25
NO992500L NO992500L (no) 1999-07-26
NO313755B1 true NO313755B1 (no) 2002-11-25

Family

ID=21861392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19992500A NO313755B1 (no) 1996-11-25 1999-05-25 2-imidazolinylaminobenzoksazolforbindelser anvendelige som <alfa>-2 adrenoceptoragonister

Country Status (18)

Country Link
US (1) US6110952A (fr)
EP (1) EP0944622A1 (fr)
JP (1) JP2001506601A (fr)
KR (1) KR20000069128A (fr)
AU (1) AU736992B2 (fr)
BR (1) BR9713537A (fr)
CA (1) CA2272683A1 (fr)
CO (1) CO4910150A1 (fr)
CZ (1) CZ183699A3 (fr)
HU (1) HUP0002966A3 (fr)
ID (1) ID22060A (fr)
IL (1) IL130094A (fr)
NO (1) NO313755B1 (fr)
PE (1) PE16599A1 (fr)
SK (1) SK74999A3 (fr)
TR (1) TR199901486T2 (fr)
WO (1) WO1998023611A1 (fr)
ZA (1) ZA9710579B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000069128A (ko) * 1996-11-25 2000-11-25 데이비드 엠 모이어 알파-2 아드레날린수용체 아고니스트로서 유용한 2-이미다졸리닐아미노벤즈옥사졸 화합물
WO2000051625A1 (fr) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibiteurs d'activite de serine protease, methodes et compositions de traitement de virus de l'herpes
WO2006044505A2 (fr) * 2004-10-13 2006-04-27 Ptc Therapeutics, Inc. Composes pour la suppression de mutations non-sens et procedes d'utilisation associes
KR20080065704A (ko) 2005-11-09 2008-07-14 콤비네이토릭스, 인코포레이티드 의학적 이상의 치료 방법들, 조성물들, 및 키트들
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
US20110003823A1 (en) * 2008-08-01 2011-01-06 Alpha Synergy Development, Inc. Compositions and methods for treatment of diseases and conditions associated with vasodilation and/or vascular leakage
US20100202979A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US20100197694A1 (en) * 2008-08-01 2010-08-05 Gerald Horn Compositions and methods for treatment of diseases and conditions with increased vascular permeability
JP5671459B2 (ja) * 2008-08-01 2015-02-18 アイ・セラピーズ・エル・エル・シー 血管収縮組成物および使用方法
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
WO2010074753A1 (fr) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Dispositifs d'inhalation et procédés associés pour administration de composés hypnotiques sédatifs
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
RU2014106367A (ru) * 2011-07-25 2015-08-27 Аллерган, Инк. N-(ИМИДАЗОЛИДИН-2-ИЛИДЕН)-ГЕТЕРОЦИКЛОПЕНТА[b]ПИРИДИНОВЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ МОДУЛЯТОРОВ АЛЬФА 2 АДРЕНЕРГИЧЕСКИХ РЕЦЕПТОРОВ

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
US3830804A (en) * 1972-11-20 1974-08-20 Eastman Kodak Co Fluorescent(pyrimidinotriazolyl)-2-styrylbenzoxazoles
US4398028A (en) * 1977-01-14 1983-08-09 Sandoz Ltd. Bicyclic heterocyclic amino derivatives
FR2521140A1 (fr) * 1982-02-05 1983-08-12 Synthelabo Derives d'imidazolidine, leur preparation et leur application en therapeutique
US5091528A (en) * 1990-09-12 1992-02-25 Allergan, Inc. 6- or 7- (2-imino-2-imidazolidine)-1,4-benzoxazines as α adrenergic agents
GB9110017D0 (en) * 1991-05-09 1991-07-03 Nat Res Dev Spectroscopic investigation using organometallic compounds
WO1995019968A1 (fr) * 1994-01-24 1995-07-27 Allergan DERIVES AROMATIQUES 2-AMINO-IMIDAZOLE UTILISES COMME AGONISTES DE L'ADRENORECEPTEUR α-2A
WO1996004270A1 (fr) * 1994-08-04 1996-02-15 Synaptic Pharmaceutical Corporation Nouveaux derives de benzimidazole
KR100215541B1 (ko) * 1996-04-19 1999-08-16 박원훈 벤족사졸계 비선형 광학 유도체 및 이들로부터 얻어진고분자
KR20000069128A (ko) * 1996-11-25 2000-11-25 데이비드 엠 모이어 알파-2 아드레날린수용체 아고니스트로서 유용한 2-이미다졸리닐아미노벤즈옥사졸 화합물

Also Published As

Publication number Publication date
US6110952A (en) 2000-08-29
KR20000069128A (ko) 2000-11-25
CO4910150A1 (es) 2000-04-24
EP0944622A1 (fr) 1999-09-29
AU736992B2 (en) 2001-08-09
PE16599A1 (es) 1999-03-12
NO992500D0 (no) 1999-05-25
IL130094A0 (en) 2000-02-29
HUP0002966A3 (en) 2001-10-29
AU5438298A (en) 1998-06-22
JP2001506601A (ja) 2001-05-22
BR9713537A (pt) 2000-03-21
IL130094A (en) 2001-09-13
SK74999A3 (en) 2000-02-14
TR199901486T2 (xx) 1999-10-21
ID22060A (id) 1999-08-26
ZA9710579B (en) 1998-06-25
CZ183699A3 (cs) 1999-09-15
WO1998023611A1 (fr) 1998-06-04
NO992500L (no) 1999-07-26
CA2272683A1 (fr) 1998-06-04
HUP0002966A2 (hu) 2001-09-28

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