NO312243B1 - N-substituerte 3-azabicyklo[3.2.0]heptanderivater egnet som neuroleptika - Google Patents

N-substituerte 3-azabicyklo[3.2.0]heptanderivater egnet som neuroleptika Download PDF

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Publication number
NO312243B1
NO312243B1 NO19970473A NO970473A NO312243B1 NO 312243 B1 NO312243 B1 NO 312243B1 NO 19970473 A NO19970473 A NO 19970473A NO 970473 A NO970473 A NO 970473A NO 312243 B1 NO312243 B1 NO 312243B1
Authority
NO
Norway
Prior art keywords
formula
azabicyclo
acid
substituted
compound
Prior art date
Application number
NO19970473A
Other languages
English (en)
Norwegian (no)
Other versions
NO970473L (no
NO970473D0 (no
Inventor
Gerd Steiner
Rainer Munschauer
Thomas Hoeger
Liliane Unger
Hans-Juergen Teschendorf
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of NO970473D0 publication Critical patent/NO970473D0/no
Publication of NO970473L publication Critical patent/NO970473L/no
Publication of NO312243B1 publication Critical patent/NO312243B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO19970473A 1994-08-04 1997-02-03 N-substituerte 3-azabicyklo[3.2.0]heptanderivater egnet som neuroleptika NO312243B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427648A DE4427648A1 (de) 1994-08-04 1994-08-04 N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1995/002893 WO1996004272A1 (de) 1994-08-04 1995-07-21 N-substituierte 3-azabicyclo(3.2.0)heptan-derivate als neuroleptika

Publications (3)

Publication Number Publication Date
NO970473D0 NO970473D0 (no) 1997-02-03
NO970473L NO970473L (no) 1997-04-01
NO312243B1 true NO312243B1 (no) 2002-04-15

Family

ID=6524944

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19970473A NO312243B1 (no) 1994-08-04 1997-02-03 N-substituerte 3-azabicyklo[3.2.0]heptanderivater egnet som neuroleptika

Country Status (25)

Country Link
US (1) US6028073A (es)
EP (1) EP0775135B1 (es)
JP (1) JPH10503503A (es)
CN (1) CN1066145C (es)
AT (1) ATE242236T1 (es)
AU (1) AU696230B2 (es)
BG (1) BG63633B1 (es)
CA (1) CA2196809A1 (es)
CZ (1) CZ287862B6 (es)
DE (2) DE4427648A1 (es)
DK (1) DK0775135T3 (es)
ES (1) ES2201111T3 (es)
FI (1) FI970448L (es)
HR (1) HRP950438A2 (es)
HU (1) HUT77772A (es)
MX (1) MX9700807A (es)
NO (1) NO312243B1 (es)
NZ (1) NZ290426A (es)
PL (1) PL183526B1 (es)
PT (1) PT775135E (es)
RU (1) RU2163604C2 (es)
SI (1) SI9520094B (es)
UA (1) UA44903C2 (es)
WO (1) WO1996004272A1 (es)
ZA (1) ZA956477B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
ATE520659T1 (de) * 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
TW200845977A (en) * 2007-03-30 2008-12-01 Targacept Inc Sub-type selective azabicycloalkane derivatives
WO2015006280A1 (en) * 2013-07-10 2015-01-15 Vertex Pharmaceuticals Incorporated Fused piperidine amides as modulators of ion channels
BR112016026596A2 (pt) * 2014-06-26 2017-08-15 Hoffmann La Roche Derivados de indolin-2-ona ou pirrolo-piridin-2-ona, seu uso, composição farmacêutica e combinação
WO2017076842A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives
WO2017076931A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives for use in the treatment of cns and related disorders
WO2017076932A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives useful in the treatment of cns diseases
CN108349944B (zh) 2015-11-06 2021-03-30 豪夫迈·罗氏有限公司 二氢吲哚-2-酮衍生物
WO2020239073A1 (zh) * 2019-05-30 2020-12-03 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
CZ287862B6 (en) 2001-02-14
FI970448A7 (fi) 1997-04-03
ZA956477B (en) 1997-02-03
CN1066145C (zh) 2001-05-23
ES2201111T3 (es) 2004-03-16
MX9700807A (es) 1997-05-31
NO970473L (no) 1997-04-01
SI9520094B (sl) 2002-02-28
FI970448A0 (fi) 1997-02-03
BG101220A (bg) 1997-08-29
HUT77772A (hu) 1998-08-28
PL318460A1 (en) 1997-06-09
NO970473D0 (no) 1997-02-03
EP0775135B1 (de) 2003-06-04
AU3116295A (en) 1996-03-04
CZ31097A3 (en) 1997-10-15
JPH10503503A (ja) 1998-03-31
US6028073A (en) 2000-02-22
CN1156454A (zh) 1997-08-06
BG63633B1 (bg) 2002-07-31
DK0775135T3 (da) 2003-09-29
HRP950438A2 (en) 1997-10-31
UA44903C2 (uk) 2002-03-15
PL183526B1 (pl) 2002-06-28
PT775135E (pt) 2003-10-31
CA2196809A1 (en) 1996-02-15
WO1996004272A1 (de) 1996-02-15
NZ290426A (en) 1998-02-26
DE4427648A1 (de) 1996-02-08
AU696230B2 (en) 1998-09-03
DE59510713D1 (de) 2003-07-10
EP0775135A1 (de) 1997-05-28
FI970448L (fi) 1997-04-03
SI9520094A (en) 1997-08-31
RU2163604C2 (ru) 2001-02-27
ATE242236T1 (de) 2003-06-15

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Free format text: LAPSED IN JANUARY 2003