FI970448L - N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina - Google Patents

N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina Download PDF

Info

Publication number
FI970448L
FI970448L FI970448A FI970448A FI970448L FI 970448 L FI970448 L FI 970448L FI 970448 A FI970448 A FI 970448A FI 970448 A FI970448 A FI 970448A FI 970448 L FI970448 L FI 970448L
Authority
FI
Finland
Prior art keywords
azobicyclo
neuroleptics
substituted
derivatives useful
heptane derivatives
Prior art date
Application number
FI970448A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970448A7 (fi
FI970448A0 (fi
Inventor
Gerd Steiner
Rainer Munschauer
Thomas Hoeger
Liliane Unger
Hans-Juergen Teschendorf
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of FI970448A0 publication Critical patent/FI970448A0/fi
Publication of FI970448A7 publication Critical patent/FI970448A7/fi
Publication of FI970448L publication Critical patent/FI970448L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI970448A 1994-08-04 1995-07-21 N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina FI970448L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427648A DE4427648A1 (de) 1994-08-04 1994-08-04 N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1995/002893 WO1996004272A1 (de) 1994-08-04 1995-07-21 N-substituierte 3-azabicyclo(3.2.0)heptan-derivate als neuroleptika

Publications (3)

Publication Number Publication Date
FI970448A0 FI970448A0 (fi) 1997-02-03
FI970448A7 FI970448A7 (fi) 1997-04-03
FI970448L true FI970448L (fi) 1997-04-03

Family

ID=6524944

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970448A FI970448L (fi) 1994-08-04 1995-07-21 N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina

Country Status (25)

Country Link
US (1) US6028073A (es)
EP (1) EP0775135B1 (es)
JP (1) JPH10503503A (es)
CN (1) CN1066145C (es)
AT (1) ATE242236T1 (es)
AU (1) AU696230B2 (es)
BG (1) BG63633B1 (es)
CA (1) CA2196809A1 (es)
CZ (1) CZ287862B6 (es)
DE (2) DE4427648A1 (es)
DK (1) DK0775135T3 (es)
ES (1) ES2201111T3 (es)
FI (1) FI970448L (es)
HR (1) HRP950438A2 (es)
HU (1) HUT77772A (es)
MX (1) MX9700807A (es)
NO (1) NO312243B1 (es)
NZ (1) NZ290426A (es)
PL (1) PL183526B1 (es)
PT (1) PT775135E (es)
RU (1) RU2163604C2 (es)
SI (1) SI9520094B (es)
UA (1) UA44903C2 (es)
WO (1) WO1996004272A1 (es)
ZA (1) ZA956477B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836406A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
ATE520659T1 (de) * 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
TW200845977A (en) * 2007-03-30 2008-12-01 Targacept Inc Sub-type selective azabicycloalkane derivatives
WO2015006280A1 (en) * 2013-07-10 2015-01-15 Vertex Pharmaceuticals Incorporated Fused piperidine amides as modulators of ion channels
BR112016026596A2 (pt) * 2014-06-26 2017-08-15 Hoffmann La Roche Derivados de indolin-2-ona ou pirrolo-piridin-2-ona, seu uso, composição farmacêutica e combinação
WO2017076842A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives
WO2017076931A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives for use in the treatment of cns and related disorders
WO2017076932A1 (en) 2015-11-06 2017-05-11 F. Hoffmann-La Roche Ag Indolin-2-one derivatives useful in the treatment of cns diseases
CN108349944B (zh) 2015-11-06 2021-03-30 豪夫迈·罗氏有限公司 二氢吲哚-2-酮衍生物
WO2020239073A1 (zh) * 2019-05-30 2020-12-03 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
CZ287862B6 (en) 2001-02-14
FI970448A7 (fi) 1997-04-03
ZA956477B (en) 1997-02-03
CN1066145C (zh) 2001-05-23
ES2201111T3 (es) 2004-03-16
MX9700807A (es) 1997-05-31
NO970473L (no) 1997-04-01
SI9520094B (sl) 2002-02-28
FI970448A0 (fi) 1997-02-03
BG101220A (bg) 1997-08-29
HUT77772A (hu) 1998-08-28
PL318460A1 (en) 1997-06-09
NO970473D0 (no) 1997-02-03
EP0775135B1 (de) 2003-06-04
AU3116295A (en) 1996-03-04
CZ31097A3 (en) 1997-10-15
JPH10503503A (ja) 1998-03-31
US6028073A (en) 2000-02-22
CN1156454A (zh) 1997-08-06
BG63633B1 (bg) 2002-07-31
DK0775135T3 (da) 2003-09-29
HRP950438A2 (en) 1997-10-31
NO312243B1 (no) 2002-04-15
UA44903C2 (uk) 2002-03-15
PL183526B1 (pl) 2002-06-28
PT775135E (pt) 2003-10-31
CA2196809A1 (en) 1996-02-15
WO1996004272A1 (de) 1996-02-15
NZ290426A (en) 1998-02-26
DE4427648A1 (de) 1996-02-08
AU696230B2 (en) 1998-09-03
DE59510713D1 (de) 2003-07-10
EP0775135A1 (de) 1997-05-28
SI9520094A (en) 1997-08-31
RU2163604C2 (ru) 2001-02-27
ATE242236T1 (de) 2003-06-15

Similar Documents

Publication Publication Date Title
FI954979A7 (fi) Kemoherkistävinä aineina käytettävät 10,11-metanodibentsosuberaanijohdannaiset
DE69736711D1 (de) Substituierte 6,5-heterobicyclische-derivate
FI954651A7 (fi) Mahdollisesti substituoidut 6,8-kinoliinit
PT775126E (pt) 1,1-dioxidos de 1,4-benzotiazepina hipolipidemica
IS4970A (is) Setnar 6,6-heteró-bísýklískar afleiður
FI961809L (fi) Uudet (R)-5-karbamoyyli-8-fluori-3-N,N-disubstituoitu-amino 3,4-dihydro-2H-1-bentsopyraanit
DK1000048T3 (da) Substituerede 1,2,3,4-tetrahydronapthalenderivater
NO951442D0 (no) 3,5-disubstituerte tetrahydrofuran-2-oner
FI952424L (fi) 11,21-bisfenyyli-19-norpregaanijohdannaisia
ATE231847T1 (de) Substituierte 1,2,3,4- tetrahydronaphthalinderivate
DE69618634D1 (de) 1,4-benzodioxin-derivate
DE59507222D1 (de) Substituierte 1,2,3,4-tetrahydro-5-nitro-pyrimidine
FI945957L (fi) N-substituoidut 3-atsabisyklo/3.2.0/heptaanijohdannaiset neurolepteinä jne.
FI970448L (fi) N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina
BR9609884A (pt) N-aril- 1,2,4-triazolin-5-onas
FI962323L (fi) N-substituoidut atsabisykloheptaanijohdannaiset, kuten esim. neuroleptit
FI970449A7 (fi) N-substituoituja atsabisykloheptaanijohdannaisia, jotka ovat käyttökel poisia neuroleptisinä aineina
FR2713641B1 (fr) Dérivés de l'épi-épibatidine.
DE59308564D1 (de) 2,4-Dialkyl-6-sec-alkylphenole
FI941149A7 (fi) 2,4-diamino-3-hydroksikarboksyylihapon johdannaisia
TR28915A (tr) Naftokinon türevleri.
FI931794L (fi) Monokvaternaera 2,16-bispiperidinylandrostanderivat
DE69722064D1 (de) 1,25-Dihydroxy-16,22,23-trisdehydro-Cholecalciferol-Derivate
BR9408162A (pt) Derivados de ácido 2,3,5,6-tetrafluorbenzóico
BR9510036A (pt) Derivados de 1,3,4-oxadiazina