DK0775135T3 - N-Substituerede 3-azabicyclo[3.2.0]heptanderivater som neuroleptika - Google Patents

N-Substituerede 3-azabicyclo[3.2.0]heptanderivater som neuroleptika

Info

Publication number
DK0775135T3
DK0775135T3 DK95926970T DK95926970T DK0775135T3 DK 0775135 T3 DK0775135 T3 DK 0775135T3 DK 95926970 T DK95926970 T DK 95926970T DK 95926970 T DK95926970 T DK 95926970T DK 0775135 T3 DK0775135 T3 DK 0775135T3
Authority
DK
Denmark
Prior art keywords
azabicyclo
pct
neuroleptics
substituted
heptane derivatives
Prior art date
Application number
DK95926970T
Other languages
English (en)
Inventor
Gerd Steiner
Rainer Munschauer
Liliane Unger
Hans-Juergen Teschendorf
Thomas Hoeger
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Application granted granted Critical
Publication of DK0775135T3 publication Critical patent/DK0775135T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK95926970T 1994-08-04 1995-07-21 N-Substituerede 3-azabicyclo[3.2.0]heptanderivater som neuroleptika DK0775135T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427648A DE4427648A1 (de) 1994-08-04 1994-08-04 N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1995/002893 WO1996004272A1 (de) 1994-08-04 1995-07-21 N-substituierte 3-azabicyclo(3.2.0)heptan-derivate als neuroleptika

Publications (1)

Publication Number Publication Date
DK0775135T3 true DK0775135T3 (da) 2003-09-29

Family

ID=6524944

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95926970T DK0775135T3 (da) 1994-08-04 1995-07-21 N-Substituerede 3-azabicyclo[3.2.0]heptanderivater som neuroleptika

Country Status (25)

Country Link
US (1) US6028073A (da)
EP (1) EP0775135B1 (da)
JP (1) JPH10503503A (da)
CN (1) CN1066145C (da)
AT (1) ATE242236T1 (da)
AU (1) AU696230B2 (da)
BG (1) BG63633B1 (da)
CA (1) CA2196809A1 (da)
CZ (1) CZ287862B6 (da)
DE (2) DE4427648A1 (da)
DK (1) DK0775135T3 (da)
ES (1) ES2201111T3 (da)
FI (1) FI970448A (da)
HR (1) HRP950438A2 (da)
HU (1) HUT77772A (da)
MX (1) MX9700807A (da)
NO (1) NO312243B1 (da)
NZ (1) NZ290426A (da)
PL (1) PL183526B1 (da)
PT (1) PT775135E (da)
RU (1) RU2163604C2 (da)
SI (1) SI9520094B (da)
UA (1) UA44903C2 (da)
WO (1) WO1996004272A1 (da)
ZA (1) ZA956477B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
CA2583333C (en) * 2004-10-14 2013-05-14 Abbott Gmbh & Co. Kg Azabicycloheptyl compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor
KR102306951B1 (ko) 2013-07-10 2021-10-01 버텍스 파마슈티칼스 인코포레이티드 이온 채널의 조절제로서의 융합된 피페리딘 아미드
EA033420B1 (ru) * 2014-06-26 2019-10-31 Hoffmann La Roche Производные индолин-2-она или пирролопиридин-2-она, обладающие антипсихотической активностью
EP3371168B1 (en) 2015-11-06 2020-05-27 H. Hoffnabb-La Roche Ag Indolin-2-one derivatives
CN108137555B (zh) 2015-11-06 2021-02-19 豪夫迈·罗氏有限公司 可用于治疗cns疾病的二氢吲哚-2-酮衍生物
CN108349942B (zh) 2015-11-06 2021-03-30 豪夫迈·罗氏有限公司 用于治疗cns和相关疾病的二氢吲哚-2-酮衍生物
EP3371174B1 (en) 2015-11-06 2021-03-17 H. Hoffnabb-La Roche Ag Indolin-2-one derivatives
US20220227773A1 (en) * 2019-05-30 2022-07-21 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Fused ring compound, preparation method therefor and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
DE59510713D1 (de) 2003-07-10
ES2201111T3 (es) 2004-03-16
SI9520094A (en) 1997-08-31
RU2163604C2 (ru) 2001-02-27
UA44903C2 (uk) 2002-03-15
PT775135E (pt) 2003-10-31
CZ287862B6 (en) 2001-02-14
ATE242236T1 (de) 2003-06-15
NO312243B1 (no) 2002-04-15
CA2196809A1 (en) 1996-02-15
NO970473L (no) 1997-04-01
US6028073A (en) 2000-02-22
CZ31097A3 (en) 1997-10-15
ZA956477B (en) 1997-02-03
BG63633B1 (bg) 2002-07-31
NZ290426A (en) 1998-02-26
AU696230B2 (en) 1998-09-03
PL183526B1 (pl) 2002-06-28
FI970448A0 (fi) 1997-02-03
EP0775135B1 (de) 2003-06-04
MX9700807A (es) 1997-05-31
BG101220A (en) 1997-08-29
NO970473D0 (no) 1997-02-03
DE4427648A1 (de) 1996-02-08
AU3116295A (en) 1996-03-04
PL318460A1 (en) 1997-06-09
HRP950438A2 (en) 1997-10-31
CN1156454A (zh) 1997-08-06
JPH10503503A (ja) 1998-03-31
WO1996004272A1 (de) 1996-02-15
EP0775135A1 (de) 1997-05-28
HUT77772A (hu) 1998-08-28
SI9520094B (sl) 2002-02-28
FI970448A (fi) 1997-04-03
CN1066145C (zh) 2001-05-23

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