NO311673B1 - Fenyl-okso-alkyl-(4-piperidinyl)benzoatderivater - Google Patents
Fenyl-okso-alkyl-(4-piperidinyl)benzoatderivater Download PDFInfo
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- NO311673B1 NO311673B1 NO19971375A NO971375A NO311673B1 NO 311673 B1 NO311673 B1 NO 311673B1 NO 19971375 A NO19971375 A NO 19971375A NO 971375 A NO971375 A NO 971375A NO 311673 B1 NO311673 B1 NO 311673B1
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- 150000001875 compounds Chemical class 0.000 claims description 103
- -1 1-[4-oxo-4-(3,4,5-trimethoxyphenyl)butyl]-4-piperidyl-4-amino-5-chloro-2,3-dihydro-7 -benzofurancarboxylate Chemical compound 0.000 claims description 26
- 239000002253 acid Substances 0.000 claims description 22
- 239000000460 chlorine Substances 0.000 claims description 22
- 150000003254 radicals Chemical class 0.000 claims description 22
- 239000001257 hydrogen Substances 0.000 claims description 21
- 229910052739 hydrogen Inorganic materials 0.000 claims description 21
- 210000001072 colon Anatomy 0.000 claims description 19
- 150000003839 salts Chemical class 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- 230000004899 motility Effects 0.000 claims description 11
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims description 8
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 7
- 229910052801 chlorine Inorganic materials 0.000 claims description 7
- 150000002431 hydrogen Chemical class 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
- 229910052736 halogen Inorganic materials 0.000 claims description 6
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- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Substances C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims description 6
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- 125000003545 alkoxy group Chemical group 0.000 claims description 5
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- 125000004448 alkyl carbonyl group Chemical group 0.000 claims description 5
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- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 4
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- 238000001665 trituration Methods 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 235000012431 wafers Nutrition 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94202791 | 1994-09-27 | ||
| US45477695A | 1995-05-31 | 1995-05-31 | |
| PCT/EP1995/003690 WO1996010026A1 (en) | 1994-09-27 | 1995-09-19 | Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO971375D0 NO971375D0 (no) | 1997-03-24 |
| NO971375L NO971375L (no) | 1997-05-05 |
| NO311673B1 true NO311673B1 (no) | 2002-01-02 |
Family
ID=26136611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19971375A NO311673B1 (no) | 1994-09-27 | 1997-03-24 | Fenyl-okso-alkyl-(4-piperidinyl)benzoatderivater |
Country Status (7)
| Country | Link |
|---|---|
| CZ (1) | CZ288942B6 (hu) |
| HU (1) | HUT77311A (hu) |
| IL (1) | IL115412A (hu) |
| MY (1) | MY117105A (hu) |
| NO (1) | NO311673B1 (hu) |
| NZ (1) | NZ293604A (hu) |
| PL (1) | PL182174B1 (hu) |
-
1995
- 1995-09-19 PL PL95319998A patent/PL182174B1/pl not_active IP Right Cessation
- 1995-09-19 NZ NZ293604A patent/NZ293604A/en not_active IP Right Cessation
- 1995-09-19 CZ CZ1997919A patent/CZ288942B6/cs not_active IP Right Cessation
- 1995-09-19 HU HU9701818A patent/HUT77311A/hu unknown
- 1995-09-22 IL IL11541295A patent/IL115412A/xx not_active IP Right Cessation
- 1995-09-26 MY MYPI95002871A patent/MY117105A/en unknown
-
1997
- 1997-03-24 NO NO19971375A patent/NO311673B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MY117105A (en) | 2004-05-31 |
| CZ91997A3 (en) | 1997-12-17 |
| IL115412A (en) | 2000-02-17 |
| IL115412A0 (en) | 1995-12-31 |
| NZ293604A (en) | 1998-07-28 |
| PL319998A1 (en) | 1997-09-01 |
| HUT77311A (hu) | 1998-03-30 |
| MX9702356A (es) | 1997-10-31 |
| NO971375D0 (no) | 1997-03-24 |
| PL182174B1 (pl) | 2001-11-30 |
| CZ288942B6 (cs) | 2001-10-17 |
| NO971375L (no) | 1997-05-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |