NO311575B1 - Hydroksylholdige indolokarbazoler, farmasöytisk preparat inneholdende slike forbindelser og anvendelse derav - Google Patents
Hydroksylholdige indolokarbazoler, farmasöytisk preparat inneholdende slike forbindelser og anvendelse derav Download PDFInfo
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- NO311575B1 NO311575B1 NO19974580A NO974580A NO311575B1 NO 311575 B1 NO311575 B1 NO 311575B1 NO 19974580 A NO19974580 A NO 19974580A NO 974580 A NO974580 A NO 974580A NO 311575 B1 NO311575 B1 NO 311575B1
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- Norway
- Prior art keywords
- indolocarbazole
- esters
- compound
- mmol
- ester
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
- C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/417,611 US5650407A (en) | 1995-04-05 | 1995-04-05 | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| US08/624,707 US5686444A (en) | 1995-04-05 | 1996-03-26 | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| PCT/US1996/004568 WO1996031515A1 (en) | 1995-04-05 | 1996-04-03 | Selected soluble esters of hydroxyl-containing indolocarbazoles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974580D0 NO974580D0 (no) | 1997-10-03 |
| NO974580L NO974580L (no) | 1997-11-27 |
| NO311575B1 true NO311575B1 (no) | 2001-12-10 |
Family
ID=27023791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19974580A NO311575B1 (no) | 1995-04-05 | 1997-10-03 | Hydroksylholdige indolokarbazoler, farmasöytisk preparat inneholdende slike forbindelser og anvendelse derav |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5686444A (ko) |
| EP (1) | EP0827505B1 (ko) |
| JP (1) | JPH11504623A (ko) |
| KR (1) | KR100429117B1 (ko) |
| AT (1) | ATE225793T1 (ko) |
| AU (1) | AU700658B2 (ko) |
| BR (1) | BR9608044A (ko) |
| CA (1) | CA2215111A1 (ko) |
| DE (1) | DE69624236T2 (ko) |
| DK (1) | DK0827505T3 (ko) |
| ES (1) | ES2183941T3 (ko) |
| HK (1) | HK1009370A1 (ko) |
| NO (1) | NO311575B1 (ko) |
| NZ (1) | NZ306205A (ko) |
| PT (1) | PT827505E (ko) |
| WO (1) | WO1996031515A1 (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686444A (en) | 1995-04-05 | 1997-11-11 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| AU2012199A (en) * | 1997-12-24 | 1999-07-19 | Vertex Pharmaceuticals Incorporated | Prodrugs of aspartyl protease inhibitors |
| US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| ATE361752T1 (de) * | 1998-09-25 | 2007-06-15 | Cephalon Inc | Methoden zur prophylaxe und behandlung von schäden der wahrnehmungshärchenzellen und der cochlearen neuronen |
| US7129250B2 (en) | 2000-05-19 | 2006-10-31 | Aegera Therapeutics Inc. | Neuroprotective and anti-proliferative compounds |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1500989A (fr) * | 1966-08-30 | 1967-11-10 | Produits cosmétiques pour les soins de la peau | |
| GB1317185A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Acyloxy-3alpha-hydroxy-pregnones |
| US4534899A (en) * | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
| US4894226A (en) * | 1986-11-14 | 1990-01-16 | Cetus Corporation | Solubilization of proteins for pharmaceutical compositions using polyproline conjugation |
| JPH0826036B2 (ja) * | 1987-01-22 | 1996-03-13 | 協和醗酵工業株式会社 | 生理活性物質ｋ−２５２の誘導体 |
| US4923986A (en) * | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
| JPH07113027B2 (ja) * | 1987-12-24 | 1995-12-06 | 協和醗酵工業株式会社 | Ｋ−２５２誘導体 |
| JPH07505124A (ja) * | 1991-11-08 | 1995-06-08 | ザ ユニバーシティ オブ サザン カリフォルニア | ニューロトロフィン活性増強のためのｋ−２５２化合物を含む組成物 |
| US5461146A (en) * | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
| WO1994006799A1 (fr) * | 1992-09-21 | 1994-03-31 | Kyowa Hakko Kogyo Co., Ltd. | Remede contre la thrombopenie |
| WO1994020106A1 (en) * | 1993-03-03 | 1994-09-15 | Kyowa Hakko Kogyo Co., Ltd. | Sensitivity enhancer for antineoplastic agent |
| JP3344586B2 (ja) * | 1993-05-28 | 2002-11-11 | セファロン，インコーポレイテッド | インドロカルバゾール誘導体を含有する前立腺病理疾患の治療剤 |
| US5686444A (en) | 1995-04-05 | 1997-11-11 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| US5650407A (en) | 1995-04-05 | 1997-07-22 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
-
1996
- 1996-03-26 US US08/624,707 patent/US5686444A/en not_active Ceased
- 1996-04-03 DK DK96911556T patent/DK0827505T3/da active
- 1996-04-03 KR KR1019970706993A patent/KR100429117B1/ko not_active IP Right Cessation
- 1996-04-03 EP EP96911556A patent/EP0827505B1/en not_active Expired - Lifetime
- 1996-04-03 AU AU54408/96A patent/AU700658B2/en not_active Ceased
- 1996-04-03 JP JP8530454A patent/JPH11504623A/ja not_active Ceased
- 1996-04-03 BR BRPI9608044-2A patent/BR9608044A/pt not_active IP Right Cessation
- 1996-04-03 WO PCT/US1996/004568 patent/WO1996031515A1/en active IP Right Grant
- 1996-04-03 DE DE69624236T patent/DE69624236T2/de not_active Expired - Fee Related
- 1996-04-03 CA CA002215111A patent/CA2215111A1/en not_active Abandoned
- 1996-04-03 PT PT96911556T patent/PT827505E/pt unknown
- 1996-04-03 ES ES96911556T patent/ES2183941T3/es not_active Expired - Lifetime
- 1996-04-03 NZ NZ306205A patent/NZ306205A/xx not_active IP Right Cessation
- 1996-04-03 AT AT96911556T patent/ATE225793T1/de not_active IP Right Cessation
-
1997
- 1997-10-03 NO NO19974580A patent/NO311575B1/no not_active IP Right Cessation
-
1998
- 1998-09-01 HK HK98110361A patent/HK1009370A1/xx not_active IP Right Cessation
-
2001
- 2001-03-19 US US09/811,725 patent/USRE38332E1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0827505A4 (en) | 1998-08-12 |
| PT827505E (pt) | 2003-01-31 |
| CA2215111A1 (en) | 1996-10-10 |
| NO974580D0 (no) | 1997-10-03 |
| AU700658B2 (en) | 1999-01-14 |
| NZ306205A (en) | 2000-01-28 |
| USRE38332E1 (en) | 2003-11-25 |
| ATE225793T1 (de) | 2002-10-15 |
| DE69624236D1 (de) | 2002-11-14 |
| DK0827505T3 (da) | 2003-02-17 |
| JPH11504623A (ja) | 1999-04-27 |
| DE69624236T2 (de) | 2003-09-11 |
| NO974580L (no) | 1997-11-27 |
| ES2183941T3 (es) | 2003-04-01 |
| KR100429117B1 (ko) | 2004-07-19 |
| MX9707632A (es) | 1998-06-30 |
| HK1009370A1 (en) | 1999-06-04 |
| US5686444A (en) | 1997-11-11 |
| EP0827505B1 (en) | 2002-10-09 |
| AU5440896A (en) | 1996-10-23 |
| KR19980703588A (ko) | 1998-11-05 |
| BR9608044A (pt) | 1999-01-26 |
| WO1996031515A1 (en) | 1996-10-10 |
| EP0827505A1 (en) | 1998-03-11 |
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| MM1K | Lapsed by not paying the annual fees |