PT827505E - Esteres de hidroxilo soluveis seleccionados contendo indolocarbazoles - Google Patents

Esteres de hidroxilo soluveis seleccionados contendo indolocarbazoles

Info

Publication number
PT827505E
PT827505E PT96911556T PT96911556T PT827505E PT 827505 E PT827505 E PT 827505E PT 96911556 T PT96911556 T PT 96911556T PT 96911556 T PT96911556 T PT 96911556T PT 827505 E PT827505 E PT 827505E
Authority
PT
Portugal
Prior art keywords
solued
self
esters containing
hydroxyl esters
indolocarbazoles
Prior art date
Application number
PT96911556T
Other languages
English (en)
Inventor
John P Mallamo
Robert L Hudkins
Original Assignee
Cephalon Inc
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/417,611 external-priority patent/US5650407A/en
Application filed by Cephalon Inc, Kyowa Hakko Kogyo Kk filed Critical Cephalon Inc
Publication of PT827505E publication Critical patent/PT827505E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
PT96911556T 1995-04-05 1996-04-03 Esteres de hidroxilo soluveis seleccionados contendo indolocarbazoles PT827505E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/417,611 US5650407A (en) 1995-04-05 1995-04-05 Selected soluble esters of hydroxyl-containing indolocarbazoles
US08/624,707 US5686444A (en) 1995-04-05 1996-03-26 Selected soluble esters of hydroxyl-containing indolocarbazoles

Publications (1)

Publication Number Publication Date
PT827505E true PT827505E (pt) 2003-01-31

Family

ID=27023791

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96911556T PT827505E (pt) 1995-04-05 1996-04-03 Esteres de hidroxilo soluveis seleccionados contendo indolocarbazoles

Country Status (16)

Country Link
US (2) US5686444A (pt)
EP (1) EP0827505B1 (pt)
JP (1) JPH11504623A (pt)
KR (1) KR100429117B1 (pt)
AT (1) ATE225793T1 (pt)
AU (1) AU700658B2 (pt)
BR (1) BR9608044A (pt)
CA (1) CA2215111A1 (pt)
DE (1) DE69624236T2 (pt)
DK (1) DK0827505T3 (pt)
ES (1) ES2183941T3 (pt)
HK (1) HK1009370A1 (pt)
NO (1) NO311575B1 (pt)
NZ (1) NZ306205A (pt)
PT (1) PT827505E (pt)
WO (1) WO1996031515A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686444A (en) 1995-04-05 1997-11-11 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles
AU2012199A (en) * 1997-12-24 1999-07-19 Vertex Pharmaceuticals Incorporated Prodrugs of aspartyl protease inhibitors
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
CN1329034C (zh) * 1998-09-25 2007-08-01 赛福伦公司 预防/治疗感觉毛细胞和耳蜗神经元损伤的药物
US7129250B2 (en) 2000-05-19 2006-10-31 Aegera Therapeutics Inc. Neuroprotective and anti-proliferative compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1500989A (fr) * 1966-08-30 1967-11-10 Produits cosmétiques pour les soins de la peau
GB1317185A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Acyloxy-3alpha-hydroxy-pregnones
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4894226A (en) * 1986-11-14 1990-01-16 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
JPH0826036B2 (ja) * 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質k−252の誘導体
WO1988007045A1 (en) * 1987-03-09 1988-09-22 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance k-252
JPH07113027B2 (ja) * 1987-12-24 1995-12-06 協和醗酵工業株式会社 K−252誘導体
WO1993008809A1 (en) * 1991-11-08 1993-05-13 The University Of Southern California Compositions containing k-252 compounds for potentiation of neurotrophin activity
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
CA2123895A1 (en) * 1992-09-21 1994-03-31 Tatsuya Tamaoki A therapeutic agent for thrombocytopenia
EP0643966A4 (en) * 1993-03-03 1995-08-09 Kyowa Hakko Kogyo Kk SENSITIVITY BOOSTER FOR ANTINEOPLASTIC AGENT.
NZ267337A (en) * 1993-05-28 2005-01-28 Kyowa Hakko Kogyo Kk Indolocarbazole derivatives and pharmaceutical compositions thereof
US5650407A (en) 1995-04-05 1997-07-22 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles
US5686444A (en) 1995-04-05 1997-11-11 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles

Also Published As

Publication number Publication date
NO311575B1 (no) 2001-12-10
EP0827505A1 (en) 1998-03-11
MX9707632A (es) 1998-06-30
ES2183941T3 (es) 2003-04-01
KR19980703588A (ko) 1998-11-05
US5686444A (en) 1997-11-11
NO974580L (no) 1997-11-27
DE69624236D1 (de) 2002-11-14
EP0827505A4 (en) 1998-08-12
NO974580D0 (no) 1997-10-03
AU5440896A (en) 1996-10-23
KR100429117B1 (ko) 2004-07-19
ATE225793T1 (de) 2002-10-15
USRE38332E1 (en) 2003-11-25
DE69624236T2 (de) 2003-09-11
HK1009370A1 (en) 1999-06-04
EP0827505B1 (en) 2002-10-09
DK0827505T3 (da) 2003-02-17
NZ306205A (en) 2000-01-28
AU700658B2 (en) 1999-01-14
WO1996031515A1 (en) 1996-10-10
JPH11504623A (ja) 1999-04-27
BR9608044A (pt) 1999-01-26
CA2215111A1 (en) 1996-10-10

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