ATE225793T1 - Ausgewählte lösliche ester von indolcarbazolen die hydroxyl enthalten - Google Patents

Ausgewählte lösliche ester von indolcarbazolen die hydroxyl enthalten

Info

Publication number
ATE225793T1
ATE225793T1 AT96911556T AT96911556T ATE225793T1 AT E225793 T1 ATE225793 T1 AT E225793T1 AT 96911556 T AT96911556 T AT 96911556T AT 96911556 T AT96911556 T AT 96911556T AT E225793 T1 ATE225793 T1 AT E225793T1
Authority
AT
Austria
Prior art keywords
indolecarbazoles
contain hydroxyl
soluble esters
esters
selected soluble
Prior art date
Application number
AT96911556T
Other languages
English (en)
Inventor
John P Mallamo
Robert L Hudkins
Original Assignee
Cephalon Inc
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/417,611 external-priority patent/US5650407A/en
Application filed by Cephalon Inc, Kyowa Hakko Kogyo Kk filed Critical Cephalon Inc
Application granted granted Critical
Publication of ATE225793T1 publication Critical patent/ATE225793T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT96911556T 1995-04-05 1996-04-03 Ausgewählte lösliche ester von indolcarbazolen die hydroxyl enthalten ATE225793T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/417,611 US5650407A (en) 1995-04-05 1995-04-05 Selected soluble esters of hydroxyl-containing indolocarbazoles
US08/624,707 US5686444A (en) 1995-04-05 1996-03-26 Selected soluble esters of hydroxyl-containing indolocarbazoles
PCT/US1996/004568 WO1996031515A1 (en) 1995-04-05 1996-04-03 Selected soluble esters of hydroxyl-containing indolocarbazoles

Publications (1)

Publication Number Publication Date
ATE225793T1 true ATE225793T1 (de) 2002-10-15

Family

ID=27023791

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96911556T ATE225793T1 (de) 1995-04-05 1996-04-03 Ausgewählte lösliche ester von indolcarbazolen die hydroxyl enthalten

Country Status (16)

Country Link
US (2) US5686444A (de)
EP (1) EP0827505B1 (de)
JP (1) JPH11504623A (de)
KR (1) KR100429117B1 (de)
AT (1) ATE225793T1 (de)
AU (1) AU700658B2 (de)
BR (1) BR9608044A (de)
CA (1) CA2215111A1 (de)
DE (1) DE69624236T2 (de)
DK (1) DK0827505T3 (de)
ES (1) ES2183941T3 (de)
HK (1) HK1009370A1 (de)
NO (1) NO311575B1 (de)
NZ (1) NZ306205A (de)
PT (1) PT827505E (de)
WO (1) WO1996031515A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686444A (en) 1995-04-05 1997-11-11 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles
WO1999033795A1 (en) * 1997-12-24 1999-07-08 Vertex Pharmaceuticals Incorporated Prodrugs of aspartyl protease inhibitors
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
WO2000018407A1 (en) * 1998-09-25 2000-04-06 Cephalon, Inc. Methods for preventing/treating damage to sensory hair cells and cochlear neurons
US7129250B2 (en) 2000-05-19 2006-10-31 Aegera Therapeutics Inc. Neuroprotective and anti-proliferative compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1500989A (fr) * 1966-08-30 1967-11-10 Produits cosmétiques pour les soins de la peau
GB1317185A (en) * 1969-06-20 1973-05-16 Glaxo Lab Ltd Acyloxy-3alpha-hydroxy-pregnones
US4534899A (en) * 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4894226A (en) * 1986-11-14 1990-01-16 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polyproline conjugation
JPH0826036B2 (ja) * 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質ｋ−２５２の誘導体
EP0303697B1 (de) * 1987-03-09 1997-10-01 Kyowa Hakko Kogyo Co., Ltd. Derivate des physiologisch aktiven mittels k-252
JPH07113027B2 (ja) * 1987-12-24 1995-12-06 協和醗酵工業株式会社 Ｋ−２５２誘導体
JPH07505124A (ja) * 1991-11-08 1995-06-08 ザ ユニバーシティ オブ サザン カリフォルニア ニューロトロフィン活性増強のためのｋ−２５２化合物を含む組成物
US5461146A (en) * 1992-07-24 1995-10-24 Cephalon, Inc. Selected protein kinase inhibitors for the treatment of neurological disorders
US5674867A (en) * 1992-09-21 1997-10-07 Kyowa Hakko Kogyo Co., Ltd. Indolocarbazole derivatives and therapeutic method for stimulating megakaicyocyte production
EP0643966A4 (de) * 1993-03-03 1995-08-09 Kyowa Hakko Kogyo Kk Wirkstoff zur verbesserung des empfindlichkeit für antineoplastische wirkstoffe.
NZ267337A (en) * 1993-05-28 2005-01-28 Kyowa Hakko Kogyo Kk Indolocarbazole derivatives and pharmaceutical compositions thereof
US5650407A (en) 1995-04-05 1997-07-22 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles
US5686444A (en) 1995-04-05 1997-11-11 Cephalon, Inc. Selected soluble esters of hydroxyl-containing indolocarbazoles

Also Published As

Publication number Publication date
NZ306205A (en) 2000-01-28
DE69624236T2 (de) 2003-09-11
BR9608044A (pt) 1999-01-26
KR100429117B1 (ko) 2004-07-19
DK0827505T3 (da) 2003-02-17
JPH11504623A (ja) 1999-04-27
US5686444A (en) 1997-11-11
EP0827505B1 (de) 2002-10-09
CA2215111A1 (en) 1996-10-10
PT827505E (pt) 2003-01-31
NO974580L (no) 1997-11-27
EP0827505A1 (de) 1998-03-11
AU5440896A (en) 1996-10-23
ES2183941T3 (es) 2003-04-01
DE69624236D1 (de) 2002-11-14
HK1009370A1 (en) 1999-06-04
AU700658B2 (en) 1999-01-14
USRE38332E1 (en) 2003-11-25
NO974580D0 (no) 1997-10-03
KR19980703588A (ko) 1998-11-05
EP0827505A4 (de) 1998-08-12
MX9707632A (es) 1998-06-30
NO311575B1 (no) 2001-12-10
WO1996031515A1 (en) 1996-10-10

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Legal Events

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