NO309325B1 - 5-(2-imidazolinylamino)benzimidazol-derivater, anvendelse derav, og farmasöytiske preparater omfattende slike forbindelser - Google Patents
5-(2-imidazolinylamino)benzimidazol-derivater, anvendelse derav, og farmasöytiske preparater omfattende slike forbindelser Download PDFInfo
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- NO309325B1 NO309325B1 NO962539A NO962539A NO309325B1 NO 309325 B1 NO309325 B1 NO 309325B1 NO 962539 A NO962539 A NO 962539A NO 962539 A NO962539 A NO 962539A NO 309325 B1 NO309325 B1 NO 309325B1
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- compound
- methyl
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- compounds
- hydrogen
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 91
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
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- 239000001257 hydrogen Substances 0.000 claims abstract description 19
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16986893A | 1993-12-17 | 1993-12-17 | |
| US08/349,558 US5478858A (en) | 1993-12-17 | 1994-12-08 | 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists |
| PCT/US1994/014292 WO1995016685A1 (en) | 1993-12-17 | 1994-12-15 | 5-(2-imidazolinylamino)benzimidazole derivatives, their preparation and their use as alpha-2 adrenoceptor agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962539D0 NO962539D0 (no) | 1996-06-14 |
| NO962539L NO962539L (no) | 1996-08-13 |
| NO309325B1 true NO309325B1 (no) | 2001-01-15 |
Family
ID=26865464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO962539A NO309325B1 (no) | 1993-12-17 | 1996-06-14 | 5-(2-imidazolinylamino)benzimidazol-derivater, anvendelse derav, og farmasöytiske preparater omfattende slike forbindelser |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US5478858A (ja) |
| EP (1) | EP0736022B1 (ja) |
| JP (1) | JPH09507216A (ja) |
| KR (1) | KR100385195B1 (ja) |
| CN (1) | CN1076352C (ja) |
| AT (1) | ATE250598T1 (ja) |
| AU (1) | AU699631B2 (ja) |
| BR (1) | BR9408343A (ja) |
| CA (1) | CA2179008C (ja) |
| CZ (1) | CZ286816B6 (ja) |
| DE (1) | DE69433181T2 (ja) |
| ES (1) | ES2202352T3 (ja) |
| FI (1) | FI962494A0 (ja) |
| HU (1) | HU224016B1 (ja) |
| MY (1) | MY131696A (ja) |
| NO (1) | NO309325B1 (ja) |
| NZ (1) | NZ333371A (ja) |
| PL (1) | PL180903B1 (ja) |
| RU (1) | RU2143430C1 (ja) |
| SG (1) | SG49049A1 (ja) |
| SK (1) | SK282566B6 (ja) |
| TW (1) | TW393469B (ja) |
| WO (1) | WO1995016685A1 (ja) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5478858A (en) * | 1993-12-17 | 1995-12-26 | The Procter & Gamble Company | 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists |
| EP0775134A4 (en) | 1994-08-04 | 1997-08-13 | Synaptic Pharma Corp | NEW BENZIMIDAZOLE DERIVATIVES |
| AU701042B2 (en) * | 1995-02-28 | 1999-01-21 | Aventisub Llc | Pharmaceutical composition for piperidinoalkanol compounds |
| US5677321A (en) | 1996-02-29 | 1997-10-14 | Synaptic Pharmaceutical Corporation | 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands |
| US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
| US6525018B1 (en) | 1999-05-17 | 2003-02-25 | The General Hospital Corp. | Treating eye disorders using intestinal trefoil proteins |
| BR9713536A (pt) | 1996-11-25 | 2000-11-07 | Procter & Gamble | Compostos heterocìclicos de guanidinila úteis como agonistas de adrenoceptores alfa-2 |
| TR199901467T2 (xx) * | 1996-11-25 | 1999-10-21 | The Procter & Gamble Company | Alfa-2 adrenosept�r agonistleri olarak yararl� guanidinilamino heterosikl bile�ikleri. |
| US6172095B1 (en) | 1996-11-25 | 2001-01-09 | The Procter & Gamble Company | Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists |
| US6306877B1 (en) | 1999-08-09 | 2001-10-23 | The Procter & Gamble Co. | Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists |
| ID22812A (id) * | 1996-11-25 | 1999-12-09 | Procter & Gamble | Senyawa 2-imidazolinilaminoindol yang berguna sebagai agonis adrenoseptor alfa-2 |
| CN1244864A (zh) * | 1996-11-25 | 2000-02-16 | 普罗克特和甘保尔公司 | 用作α－2肾上腺素能受体兴奋剂的2－咪唑啉基氨基吲唑化合物 |
| US6349719B2 (en) | 1997-02-24 | 2002-02-26 | Aradigm Corporation | Formulation and devices for monitoring the efficacy of the delivery of aerosols |
| US6192882B1 (en) * | 1997-02-24 | 2001-02-27 | Aradigm Corporation | Formulation and devices for monitoring the efficacy of the delivery of aerosols |
| US6495583B1 (en) | 1997-03-25 | 2002-12-17 | Synaptic Pharmaceutical Corporation | Benzimidazole derivatives |
| US20030185838A1 (en) * | 2001-11-28 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating lesions of the respiratory epithelium |
| US20030186882A1 (en) * | 2001-07-31 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating and preventing distal bowel lesions |
| ID24081A (id) * | 1997-04-15 | 2000-07-06 | Procter & Gamble | Senyawa-senyawa 5-(2-imidazolinilamino) benzimidazol yang berguna sebagai agonis-agonis alfa-2-adrenoseptor |
| SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
| EE04294B1 (et) * | 1997-08-26 | 2004-06-15 | Hoechst Marion Roussel, Inc. | Farmatseutiline kompositsioon piperidinoalkanooldekongestandi kombineerimiseks |
| JP2001524478A (ja) * | 1997-11-24 | 2001-12-04 | ザ プロクター アンド ギャンブル カンパニー | ５−（２−イミダゾリニルアミノ）−ベンゾイミダゾール誘導体類、それらの調製および改良された代謝安定性を有するアルファアドレナリン受容体作動薬としてのそれらの使用 |
| US7919119B2 (en) * | 1999-05-27 | 2011-04-05 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US8889112B2 (en) * | 1999-09-16 | 2014-11-18 | Ocularis Pharma, Llc | Ophthalmic formulations including selective alpha 1 antagonists |
| US7678387B2 (en) * | 2000-06-06 | 2010-03-16 | Capricorn Pharma, Inc. | Drug delivery systems |
| US20100196466A1 (en) * | 2000-06-06 | 2010-08-05 | Capricorn Pharma Inc. | Drug delivery system |
| US20070059367A1 (en) * | 2000-06-06 | 2007-03-15 | Cherukuri S R | Drug Delivery System and Associated Methods |
| WO2002019996A2 (en) * | 2000-09-08 | 2002-03-14 | Warner-Lambert Compan Llc | Prevention of acute sinusitis and sinus attack |
| AU2002220248A1 (en) * | 2000-11-06 | 2002-05-15 | Andrx Pharmaceuticals, Inc. | Once a day antihistamine and decongestant formulation |
| US7538082B2 (en) | 2001-04-24 | 2009-05-26 | The General Hospital Corporation | Methods and compositions for treating oral and esophageal lesions |
| US20030105016A1 (en) * | 2001-09-06 | 2003-06-05 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
| US20060189526A1 (en) * | 2002-04-24 | 2006-08-24 | Podolsky Daniel K | Compositions containing an intestinal trefoil peptide and a mucoadhesive |
| US20040171544A1 (en) * | 2001-04-24 | 2004-09-02 | Barker Nicholas P. | Trefoil domain-containing polypeptides and uses thereof |
| US20030181384A1 (en) * | 2001-09-06 | 2003-09-25 | Podolsky Daniel K. | Methods and compositions for treating vaginal, cervical, and uterine epithelial lesions |
| EP1438062A4 (en) * | 2001-10-05 | 2005-06-01 | Gen Hospital Corp | METHOD AND COMPOSITIONS FOR TREATING SKIN Lions |
| US20030185839A1 (en) * | 2001-10-05 | 2003-10-02 | Podolsky Daniel K. | Methods and compositions for treating dermal lesions |
| JP2005532988A (ja) * | 2001-11-28 | 2005-11-04 | ザ ジェネラル ホスピタル コーポレーション | 呼吸上皮の病変を治療するための方法および組成物 |
| WO2003082196A2 (en) * | 2002-03-26 | 2003-10-09 | The General Hospital Corporation | Combination therapy using trefoil peptides |
| US20040001885A1 (en) * | 2002-06-27 | 2004-01-01 | Unchalee Kositprapa | Rapidly disintegrating antihistamine formulation |
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- 1994-12-15 WO PCT/US1994/014292 patent/WO1995016685A1/en active IP Right Grant
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