NO308411B1 - <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler - Google Patents

<beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler

Info

Publication number
NO308411B1
NO308411B1 NO971952A NO971952A NO308411B1 NO 308411 B1 NO308411 B1 NO 308411B1 NO 971952 A NO971952 A NO 971952A NO 971952 A NO971952 A NO 971952A NO 308411 B1 NO308411 B1 NO 308411B1
Authority
NO
Norway
Prior art keywords
beta
substituted
meso
dihydroxy
isobacteriochlorines
Prior art date
Application number
NO971952A
Other languages
English (en)
Norwegian (no)
Other versions
NO971952L (no
NO971952D0 (no
Inventor
David Dolphin
Christian Bruckner
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of NO971952L publication Critical patent/NO971952L/no
Publication of NO971952D0 publication Critical patent/NO971952D0/no
Publication of NO308411B1 publication Critical patent/NO308411B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO971952A 1994-10-26 1997-04-25 <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler NO308411B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,577 US5648485A (en) 1994-10-26 1994-10-26 β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
PCT/CA1995/000602 WO1996013504A1 (en) 1994-10-26 1995-10-25 β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES

Publications (3)

Publication Number Publication Date
NO971952L NO971952L (no) 1997-04-25
NO971952D0 NO971952D0 (no) 1997-04-25
NO308411B1 true NO308411B1 (no) 2000-09-11

Family

ID=23286058

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971952A NO308411B1 (no) 1994-10-26 1997-04-25 <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler

Country Status (20)

Country Link
US (2) US5648485A (cs)
EP (1) EP0804439B1 (cs)
JP (2) JP3228296B2 (cs)
KR (1) KR970707129A (cs)
CN (1) CN1043143C (cs)
AT (1) ATE250064T1 (cs)
AU (1) AU704971B2 (cs)
CA (1) CA2199399C (cs)
CZ (1) CZ294496B6 (cs)
DE (1) DE69531795T2 (cs)
DK (1) DK0804439T3 (cs)
ES (1) ES2208701T3 (cs)
FI (1) FI971734A0 (cs)
HU (1) HU221102B1 (cs)
NO (1) NO308411B1 (cs)
NZ (1) NZ294203A (cs)
PL (1) PL182239B1 (cs)
PT (1) PT804439E (cs)
TW (1) TW301648B (cs)
WO (1) WO1996013504A1 (cs)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
JP2001514617A (ja) * 1997-01-21 2001-09-11 ジ・アメリカン・ナショナル・レッド・クロス 両親媒性フェノチアジン−５−イウム染料と光による全血および血液成分の細胞内および細胞外汚染除去
US6444194B1 (en) 1997-02-14 2002-09-03 Miravant Pharmaceuticals, Inc. Indium photosensitizers for PDT
FR2760841B1 (fr) * 1997-03-12 1999-04-16 Commissariat Energie Atomique Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination
DE19814405C2 (de) 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US20030176663A1 (en) * 1998-05-11 2003-09-18 Eidgenossische Technische Hochscule Specific binding molecules for scintigraphy
CA2346690C (en) 1998-10-20 2003-12-16 Jeffrey John Scheibel Laundry detergents comprising modified alkylbenzene sulfonates
KR100418820B1 (ko) 1998-10-20 2004-02-18 더 프록터 앤드 갬블 캄파니 개질된 알킬벤젠 설포네이트를 포함하는 세탁용 세제
AU4278400A (en) 1999-04-14 2000-11-14 University Of British Columbia, The Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
WO2001062800A1 (en) 2000-02-24 2001-08-30 Eidgenössische Technische Hochschule Zürich Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis
CA2408323C (en) * 2000-05-08 2012-06-12 The University Of British Columbia Drug delivery systems for photodynamic therapy
WO2001085213A2 (en) 2000-05-08 2001-11-15 The University Of British Columbia Supports for photosensitizer formulations
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
US20020197700A1 (en) * 2000-09-07 2002-12-26 Schering Ag Receptor of the EDb-fibronectin domains
DE60112769T2 (de) 2000-09-08 2006-06-08 San-Ei Gen F.F.I., Inc., Toyonaka Tetraphenylbacteriochlorinderivate und diese enthaltdenden Zusammensetzungen
US7090691B2 (en) * 2001-11-09 2006-08-15 Qlt Inc. Photodynamic therapy for the treatment of hair loss
DE60328496D1 (en) 2002-06-27 2009-09-03 Health Research Inc Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
EP2036908A3 (en) * 2002-07-02 2009-05-13 Health Research, INC. Efficient synthesis of pyropheophorbide a derivates
WO2004063200A1 (en) 2003-01-16 2004-07-29 Techno Mart Co., Ltd Porphyrin derivatives
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
GB0323358D0 (en) * 2003-10-06 2003-11-05 Green Grass Design Ltd Novel compounds and processes
JP4635493B2 (ja) * 2003-10-09 2011-02-23 日本製紙株式会社 ダル調塗工紙
GB2408265A (en) * 2003-11-21 2005-05-25 Univ Sheffield Water-soluble hyperbranched polymer porphyrins
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
WO2006089122A2 (en) 2005-02-18 2006-08-24 North Carolina State University De novo synthesis of bacteriochlorins
WO2007064841A2 (en) * 2005-11-30 2007-06-07 North Carolina State University Porphyrinic compounds for use in flow cytometry
WO2009038659A2 (en) * 2007-09-14 2009-03-26 Health Research, Inc. Organically modified silica nanoparticles with covalently incorporated photosensitizers for drug delivery in photodynamic therapy
US8253725B2 (en) * 2007-12-28 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and system for generating surface models of geometric structures
US20120034157A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
ES2707228T3 (es) * 2008-09-18 2019-04-03 Biolitec Unternehmensbeteiligungs Ii Ag Nuevo método y aplicación de porfirinas y clorinas asimétricamente meso-sustituidas para TFD
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
US9226917B2 (en) 2008-12-16 2016-01-05 Valeant Pharmaceuticals International, Inc. Photodynamic therapy for conditions of the eye
US9211283B2 (en) 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
CA2788824C (en) 2010-02-04 2019-03-12 Morphotek, Inc. Chlorotoxin polypeptides and conjugates and uses thereof
EP2870159B1 (en) * 2010-07-22 2017-06-28 biolitec Unternehmensbeteiligungs II AG APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
CN104040341B (zh) 2011-10-25 2016-12-28 斯隆－凯特林纪念癌症中心 用于前列腺癌的诊断、预测和治疗的游离psa抗体
AU2013334102B2 (en) 2012-10-26 2018-08-16 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
US10766915B2 (en) 2013-03-15 2020-09-08 Sherri Ann McFARLAND Metal-based coordination complexes as photodynamic compounds and their use
CA3142856A1 (en) 2013-12-23 2015-07-02 Memorial Sloan-Kettering Cancer Center Methods and compositions for treating cancer using peptide nucleic acid-based agents
TWI474536B (zh) 2014-07-01 2015-02-21 Nat Univ Chung Hsing 紫質光敏染料化合物以及染料敏化太陽能電池
US10456375B2 (en) 2014-09-30 2019-10-29 Biolitec Unternehmensbeteiligungs Ii Ag Specifically meso-substituted porphyrins and chlorins for photodynamic therapy
RU2615770C1 (ru) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью
AU2017371379B2 (en) * 2016-12-05 2021-08-26 Salt And Light Pharmaceuticals Pty. Ltd. Photodynamic therapeutic compounds and photodynamic methods of treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US6376483B1 (en) * 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

Also Published As

Publication number Publication date
FI971734A7 (fi) 1997-04-23
ES2208701T3 (es) 2004-06-16
JPH10507766A (ja) 1998-07-28
DK0804439T3 (da) 2004-02-02
DE69531795D1 (de) 2003-10-23
JP3228296B2 (ja) 2001-11-12
AU3695195A (en) 1996-05-23
EP0804439B1 (en) 2003-09-17
CN1161697A (zh) 1997-10-08
CA2199399C (en) 2004-02-24
WO1996013504A1 (en) 1996-05-09
PL319907A1 (en) 1997-09-01
US5831088A (en) 1998-11-03
CZ115597A3 (en) 1997-09-17
HUT77008A (hu) 1998-03-02
NO971952L (no) 1997-04-25
JP2001294589A (ja) 2001-10-23
DE69531795T2 (de) 2004-08-05
PL182239B1 (pl) 2001-11-30
CZ294496B6 (cs) 2005-01-12
FI971734L (fi) 1997-04-23
ATE250064T1 (de) 2003-10-15
AU704971B2 (en) 1999-05-13
HU221102B1 (en) 2002-08-28
CA2199399A1 (en) 1996-05-09
FI971734A0 (fi) 1997-04-23
PT804439E (pt) 2004-02-27
KR970707129A (ko) 1997-12-01
US5648485A (en) 1997-07-15
EP0804439A1 (en) 1997-11-05
NO971952D0 (no) 1997-04-25
MX9703013A (es) 1997-07-31
TW301648B (cs) 1997-04-01
CN1043143C (zh) 1999-04-28
NZ294203A (en) 1998-12-23

Similar Documents

Publication Publication Date Title
NO308411B1 (no) &lt;beta&gt;,&lt;beta&gt;&#39;-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra &lt;beta&gt;,&lt;beta&gt;&#39;-usubstituerte tetrapyrrol- makrocykler
PH31610A (en) Taxol derivatives.
PL327169A1 (en) Naphtyl-substituted derivatives of benzimidazole as anticoagulants
DE69529143D1 (en) Distamycin a analoga als antitumor- oder antivirale wirkstoffe
PL317229A1 (en) Method of stabilisingderivatives of duocarmycin
NZ315505A (en) Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands
DK0854874T3 (da) Makrocykliske lactonforbindelser og fremgangsmåde til fremstilling af disse
CS9101451A2 (en) Method of phenylisoserine derivatives stereoselective preparation
GR1002183B (en) Derivatives of n-phenylbenzamide and a method for their preparation
RU92016568A (ru) Способ получения производных бета-лактамов
NO980647L (no) Fremgangsmåte for diagnostisk bildeanalyse ved anvendelse av biokonjugater av metallkomplekser av nitrogeninneholdende makrocykliske ligander
AU3215795A (en) Indole alkaloids useful as uv protective and anti-inflammatory agents
EA199800101A1 (ru) Комплекс металла с полиаминооксидами и его применение для формирования изображений при диагностике
EA199900754A1 (ru) Способ получения замещенного тиазолидиндиона
PL309402A1 (en) Novel steroides
CA2255664A1 (en) Selenophene anti-tumor agents
JP2002538946A5 (cs)
ZA849159B (en) N-(methoxyphenacyl)-amine derivatives
EA199900684A1 (ru) Производные иминоазаантрациклинона для лечения амилоидоза
PT78288A (en) (1h-tetrazol-5-yl)tetrazolo&lt;1,5-a&gt;-quinolines and related compounds
DE3269780D1 (en) Cephalosporin derivatives and process for their preparation
EP0476156A4 (en) Solid oral preparation containing catechol compound
AU9107682A (en) 3,7alpha-diazacyclohepta(j,k)fluoriene derivatives
זאב לוי Liberté dialectique
IT1254201B (it) Procedimento per la preparazione di derivati del glicerolo otticamente attivi.

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees