NO307931B1 - Arylalkylpyridazinoner, farmasøytiske preparater og anvendelse av slike forbindelser til fremstilling av legemidler - Google Patents

Arylalkylpyridazinoner, farmasøytiske preparater og anvendelse av slike forbindelser til fremstilling av legemidler

Info

Publication number
NO307931B1
NO307931B1 NO961578A NO961578A NO307931B1 NO 307931 B1 NO307931 B1 NO 307931B1 NO 961578 A NO961578 A NO 961578A NO 961578 A NO961578 A NO 961578A NO 307931 B1 NO307931 B1 NO 307931B1
Authority
NO
Norway
Prior art keywords
arylalkylpyridazinones
pharmaceuticals
compounds
manufacture
pharmaceutical preparations
Prior art date
Application number
NO961578A
Other languages
English (en)
Norwegian (no)
Other versions
NO961578D0 (no
NO961578L (no
Inventor
Rochus Jonas
Michael Wolf
Norbert Beier
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO961578D0 publication Critical patent/NO961578D0/no
Publication of NO961578L publication Critical patent/NO961578L/no
Publication of NO307931B1 publication Critical patent/NO307931B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
NO961578A 1995-04-20 1996-04-19 Arylalkylpyridazinoner, farmasøytiske preparater og anvendelse av slike forbindelser til fremstilling av legemidler NO307931B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19514568A DE19514568A1 (de) 1995-04-20 1995-04-20 Arylalkyl-pyridazinone

Publications (3)

Publication Number Publication Date
NO961578D0 NO961578D0 (no) 1996-04-19
NO961578L NO961578L (no) 1996-10-21
NO307931B1 true NO307931B1 (no) 2000-06-19

Family

ID=7759974

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961578A NO307931B1 (no) 1995-04-20 1996-04-19 Arylalkylpyridazinoner, farmasøytiske preparater og anvendelse av slike forbindelser til fremstilling av legemidler

Country Status (21)

Country Link
US (2) US6399611B1 (fr)
EP (1) EP0738715B1 (fr)
JP (1) JP4005157B2 (fr)
KR (1) KR100428879B1 (fr)
CN (1) CN1159299C (fr)
AT (1) ATE231842T1 (fr)
AU (1) AU705025B2 (fr)
CA (1) CA2174472C (fr)
CZ (1) CZ291868B6 (fr)
DE (2) DE19514568A1 (fr)
DK (1) DK0738715T3 (fr)
ES (1) ES2191070T3 (fr)
HU (1) HU226198B1 (fr)
NO (1) NO307931B1 (fr)
PT (1) PT738715E (fr)
RU (1) RU2159236C2 (fr)
SI (1) SI0738715T1 (fr)
SK (1) SK284167B6 (fr)
TW (1) TW475927B (fr)
UA (1) UA43853C2 (fr)
ZA (1) ZA963154B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
JP4017214B2 (ja) 1996-06-11 2007-12-05 興和創薬株式会社 ５−フェニル−３−ピリダジノン誘導体
EP0924204A4 (fr) * 1996-08-27 2002-10-23 Nikken Chemicals Co Ltd Derives du 2-phenylmorpholin-5-one et composition pharmaceutique les comprenant
DE19850701A1 (de) 1998-11-04 2000-05-11 Merck Patent Gmbh Benzoylpyridazine
MXPA02001830A (es) 1999-08-21 2002-08-12 Byk Gulden Lomberg Chem Fab Combinacion sinergica de inhibidores de pde y agonista de beta 2 adrenoceptor.
DE10064997A1 (de) * 2000-12-23 2002-06-27 Merck Patent Gmbh Benzoylpyridazine
WO2002072103A1 (fr) * 2001-02-12 2002-09-19 Merck Patent Gmbh Utilisation d'inhibiteurs de phosphodiesterase de type 4 pour des maladies du myocarde
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
MXPA03010679A (es) 2001-05-23 2004-03-02 Tanabe Seiyaku Co Una composicion para acelerar la cicatrizacion de fractura osea.
MXPA03010672A (es) * 2001-05-23 2004-03-02 Tanabe Seiyaku Co Composicion para el tratamiento regenerativo de enfermedades del cartilago.
DE10150517A1 (de) * 2001-10-12 2003-04-17 Merck Patent Gmbh Verwendung von Phosphodiesterase IV-Inhibitoren
MXPA04003668A (es) * 2001-10-31 2004-07-22 Merck Patent Gmbh Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos.
US7074959B2 (en) * 2002-08-01 2006-07-11 New Mexico Highlands University Methods and systems for remediating hydrazine-contaminated equipment and/or surfaces
WO2004087211A2 (fr) 2003-04-01 2004-10-14 Applied Research Systems Ars Holding N.V. Inhibiteurs de phosphodiesterases dans l'infecondite
DE602005005638T2 (de) * 2004-02-04 2009-05-14 Nycomed Gmbh 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-on-derivate als pde4-inhibitoren
WO2005075437A1 (fr) * 2004-02-04 2005-08-18 Altana Pharma Ag Derives de pyridazinone et leur utilisation en tant qu'inhibiteurs de pde4
AR064346A1 (es) * 2006-12-14 2009-04-01 Astellas Pharma Inc Compuesto de oxicarbonilo
US8466198B2 (en) * 2008-09-02 2013-06-18 Bruce Kneller Compositions comprising creatine salts and methods of use thereof
US20110052729A1 (en) * 2009-08-26 2011-03-03 Golini Jeffrey M Pharmaceutical or nutraceutical composition
CN109153644B (zh) 2016-03-16 2022-10-21 H·李·莫菲特癌症中心研究有限公司 用以增强效应t细胞功能的针对cereblon的小分子
WO2020014489A2 (fr) 2018-07-11 2020-01-16 H. Lee Moffitt Cancer Center And Research Institute, Inc. Composés immunomodulateurs dimères visant des mécanismes à base de céréblon

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1604863A (fr) * 1967-11-22 1972-04-17
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
DE2845456A1 (de) * 1978-10-19 1980-08-14 Merck Patent Gmbh 6-arylpyridazin-3-one und verfahren zu ihrer herstellung
US4397854A (en) * 1981-05-14 1983-08-09 Warner-Lambert Company Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
US4734415A (en) * 1982-08-13 1988-03-29 Warner-Lambert Company Substituted 4,5-dihydro-6-(substituted)-phenyl-3(2H)-pyridazinones and 6-(substituted) phenyl-3(2H)-pyridazinones
ES532337A0 (es) * 1983-05-11 1985-12-01 Byk Gulden Lomberg Chem Fab Procedimiento para la preparacion de 6-aril-3 (2h)piridazinonas
US4666902A (en) * 1983-06-20 1987-05-19 Cassella Aktiengesellschaft Tetrahydropyridazinone derivatives, processes for their preparation and their use
US4816454A (en) 1984-09-21 1989-03-28 Cassella Aktiengesellschaft 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
JPS61158969A (ja) * 1984-12-24 1986-07-18 ワーナー‐ランバート・コンパニー ４，５‐ジヒドロ‐４，４‐ジアルキル‐６‐（置換）フエニル‐３（２ｈ）‐ピリダジノン類
DE3704879A1 (de) * 1987-02-17 1988-08-25 Merck Patent Gmbh Pyridazinonderivate
GB8903130D0 (en) 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
IE902881A1 (en) * 1989-08-10 1991-02-27 Glaxo Inc Pyridazinones having cardiotonic and beta blocking¹activities
DE4237656A1 (de) * 1992-06-13 1993-12-16 Merck Patent Gmbh Benzimidazolderivate
JP2806192B2 (ja) * 1992-11-02 1998-09-30 日本曹達株式会社 血小板凝集抑制剤
DE19502699A1 (de) 1995-01-28 1996-08-01 Merck Patent Gmbh Arylalkyl-thiadiazinone

Also Published As

Publication number Publication date
JPH08291145A (ja) 1996-11-05
HUP9601034A2 (en) 1996-12-30
KR100428879B1 (ko) 2004-07-15
CZ291868B6 (cs) 2003-06-18
HUP9601034A3 (en) 1999-03-01
SK284167B6 (sk) 2004-10-05
TW475927B (en) 2002-02-11
RU2159236C2 (ru) 2000-11-20
US6531473B2 (en) 2003-03-11
HU9601034D0 (en) 1996-06-28
AU5071196A (en) 1996-10-31
UA43853C2 (uk) 2002-01-15
PT738715E (pt) 2003-06-30
DE59610081D1 (de) 2003-03-06
NO961578D0 (no) 1996-04-19
EP0738715A2 (fr) 1996-10-23
NO961578L (no) 1996-10-21
AU705025B2 (en) 1999-05-13
CN1142493A (zh) 1997-02-12
ES2191070T3 (es) 2003-09-01
HU226198B1 (en) 2008-06-30
DE19514568A1 (de) 1996-10-24
ATE231842T1 (de) 2003-02-15
US6399611B1 (en) 2002-06-04
DK0738715T3 (da) 2003-05-26
ZA963154B (en) 1996-12-06
SI0738715T1 (en) 2003-10-31
CA2174472C (fr) 2008-10-21
CZ113296A3 (en) 1996-11-13
US20020111356A1 (en) 2002-08-15
CN1159299C (zh) 2004-07-28
SK48796A3 (en) 1997-02-05
EP0738715B1 (fr) 2003-01-29
KR960037662A (ko) 1996-11-19
CA2174472A1 (fr) 1996-10-21
EP0738715A3 (fr) 1998-06-17
JP4005157B2 (ja) 2007-11-07

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