NO306944B1 - Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav - Google Patents
Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse deravInfo
- Publication number
- NO306944B1 NO306944B1 NO962810A NO962810A NO306944B1 NO 306944 B1 NO306944 B1 NO 306944B1 NO 962810 A NO962810 A NO 962810A NO 962810 A NO962810 A NO 962810A NO 306944 B1 NO306944 B1 NO 306944B1
- Authority
- NO
- Norway
- Prior art keywords
- alkyl group
- lower alkyl
- substituted
- derivatives
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27095794 | 1994-11-04 | ||
| PCT/JP1995/002236 WO1996014293A1 (fr) | 1994-11-04 | 1995-11-01 | Nouveau derive de 1,3-dialkyluree ayant un groupe hydroxyle |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO962810D0 NO962810D0 (no) | 1996-07-03 |
| NO962810L NO962810L (no) | 1996-07-03 |
| NO306944B1 true NO306944B1 (no) | 2000-01-17 |
Family
ID=17493383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO962810A NO306944B1 (no) | 1994-11-04 | 1996-07-03 | Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5891912A (fr) |
| EP (1) | EP0738711B1 (fr) |
| KR (1) | KR100376150B1 (fr) |
| CN (1) | CN1055681C (fr) |
| AT (1) | ATE190304T1 (fr) |
| CA (1) | CA2180021A1 (fr) |
| DE (1) | DE69515465T2 (fr) |
| ES (1) | ES2145929T3 (fr) |
| FI (1) | FI962751A (fr) |
| NO (1) | NO306944B1 (fr) |
| WO (1) | WO1996014293A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| US5985968A (en) * | 1997-11-17 | 1999-11-16 | Air Products And Chemicals, Inc. | Surface tension reduction with N,N-dialkyl ureas |
| US6156784A (en) * | 1997-12-18 | 2000-12-05 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compounds useful as phosphotyrosine mimics |
| US6420396B1 (en) | 1998-12-16 | 2002-07-16 | Beiersdorf Ag | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| US6677360B2 (en) * | 1998-12-16 | 2004-01-13 | Bayer Aktiengesellschaft | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
| FR2820136A1 (fr) * | 2001-01-26 | 2002-08-02 | Aventis Pharma Sa | Nouveaux derives de l'uree, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation |
| US6842358B2 (en) * | 2002-08-01 | 2005-01-11 | Netlogic Microsystems, Inc. | Content addressable memory with cascaded array |
| DK1542714T3 (da) | 2002-09-18 | 2014-05-26 | Janssen Pharmaceuticals Inc | Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller |
| DE10252650A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Cyclohexyl-Harnstoff-Derivate |
| US7045653B2 (en) * | 2002-12-23 | 2006-05-16 | Pfizer, Inc. | Pharmaceuticals |
| BRPI0409627A (pt) * | 2003-04-21 | 2006-04-25 | Elan Pharm Inc | 2-hidróxi-3-diaminoalcanos de fenacila |
| CN102241742B (zh) * | 2003-08-28 | 2014-04-02 | 奥索-麦克尼尔药品公司 | 结合血小板生成素受体的肽和化合物 |
| GB2425310B (en) * | 2003-12-31 | 2008-04-16 | Council Scient Ind Res | N-aryloxypropanolyl-N' -phenethyl-urea |
| US6962945B2 (en) | 2004-03-26 | 2005-11-08 | Council Of Scientific And Industrial Research | N-aryloxypropanolyl-N′-phenethyl-urea |
| FR2885129B1 (fr) * | 2005-04-29 | 2007-06-15 | Proskelia Sas | Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation. |
| EP1965805B1 (fr) * | 2005-11-25 | 2009-12-02 | Galapagos SAS | Dérivés de l'urée utiles comme modulateurs des récepteurs du calcium |
| GB0613674D0 (en) * | 2006-07-10 | 2006-08-16 | Proskelia Sas | Derivatives of urea and related diamines, methods for their manufacture, and uses therefor |
| US9468637B2 (en) | 2009-05-13 | 2016-10-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EA019511B1 (ru) * | 2009-05-28 | 2014-04-30 | Новартис Аг | Замещенные производные аминопропионовой кислоты в качестве ингибиторов неприлизина |
| MA33364B1 (fr) | 2009-05-28 | 2012-06-01 | Novartis Ag | Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine |
| JO2967B1 (en) | 2009-11-20 | 2016-03-15 | نوفارتس ايه جي | Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors |
| CN102971288B (zh) * | 2010-04-30 | 2015-01-21 | 日产化学工业株式会社 | 二氨基苯基烷基脲的新制造方法 |
| SI2956464T1 (en) | 2013-02-14 | 2018-08-31 | Novartis Ag | Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors (neutral endopeptidases) |
| JP6301371B2 (ja) | 2013-02-14 | 2018-04-11 | ノバルティス アーゲー | インビボ効力が改善されたｎｅｐ阻害剤としての置換ビスフェニルブタン酸誘導体 |
| US9801882B2 (en) | 2013-02-17 | 2017-10-31 | Intra-Cellular Therapies, Inc. | Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases |
| WO2016022893A1 (fr) | 2014-08-07 | 2016-02-11 | Intra-Cellular Therapies, Inc. | Composés organiques |
| JP2019510039A (ja) | 2016-03-28 | 2019-04-11 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 新規組成物および方法 |
| EP3746081A4 (fr) | 2018-01-31 | 2021-10-27 | Intra-Cellular Therapies, Inc. | Nouvelles utilisations |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CY1406A (en) * | 1980-12-18 | 1988-04-22 | Schering Corp | Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase |
| IE53315B1 (en) * | 1980-12-18 | 1988-10-12 | Schering Corp | Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase |
| DE3134933A1 (de) * | 1981-09-03 | 1983-03-31 | Hoechst Ag, 6230 Frankfurt | "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung" |
| JPS5823851A (ja) * | 1982-07-29 | 1983-02-12 | Mitsubishi Gas Chem Co Inc | 耐熱性樹脂組成物 |
| US4668769A (en) * | 1985-08-02 | 1987-05-26 | Hoover Dennis J | Oxa- and azahomocyclostatine polypeptides |
| US4599198A (en) * | 1985-08-02 | 1986-07-08 | Pfizer Inc. | Intermediates in polypeptide synthesis |
| CA1297631C (fr) * | 1985-12-23 | 1992-03-17 | Sesha I. Natarajan | Inhibiteurs de la renine a groupement ureido |
| US4757050A (en) * | 1985-12-23 | 1988-07-12 | E. R. Squibb Sons, Inc. | Ureido renin inhibitors |
| DE3619508A1 (de) * | 1986-06-10 | 1987-12-17 | Merck Patent Gmbh | Aminosaeurederivate |
| JP2775690B2 (ja) * | 1989-08-22 | 1998-07-16 | 昭和シェル石油株式会社 | スリップ・レイヤー・シート |
| US5475027A (en) * | 1990-11-19 | 1995-12-12 | G.D. Searle & Co. | Retroviral protease inhibitors |
| DE69126987T2 (de) * | 1990-11-19 | 1998-03-05 | Monsanto Co | Retrovirale protease-inhibitoren |
| JPH0672985A (ja) * | 1992-08-28 | 1994-03-15 | Ono Pharmaceut Co Ltd | （チオ）ウレア誘導体 |
| JP3118738B2 (ja) * | 1992-12-22 | 2000-12-18 | 小野薬品工業株式会社 | （チオ）ウレア誘導体 |
-
1995
- 1995-11-01 EP EP95936083A patent/EP0738711B1/fr not_active Expired - Lifetime
- 1995-11-01 US US08/663,239 patent/US5891912A/en not_active Expired - Fee Related
- 1995-11-01 ES ES95936083T patent/ES2145929T3/es not_active Expired - Lifetime
- 1995-11-01 WO PCT/JP1995/002236 patent/WO1996014293A1/fr active IP Right Grant
- 1995-11-01 CA CA002180021A patent/CA2180021A1/fr not_active Abandoned
- 1995-11-01 CN CN95191137A patent/CN1055681C/zh not_active Expired - Fee Related
- 1995-11-01 AT AT95936083T patent/ATE190304T1/de not_active IP Right Cessation
- 1995-11-01 DE DE69515465T patent/DE69515465T2/de not_active Expired - Fee Related
- 1995-11-01 KR KR1019960703618A patent/KR100376150B1/ko not_active IP Right Cessation
-
1996
- 1996-07-03 NO NO962810A patent/NO306944B1/no not_active IP Right Cessation
- 1996-07-04 FI FI962751A patent/FI962751A/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5891912A (en) | 1999-04-06 |
| CN1138321A (zh) | 1996-12-18 |
| FI962751A0 (fi) | 1996-07-04 |
| CN1055681C (zh) | 2000-08-23 |
| EP0738711A4 (fr) | 1998-09-30 |
| KR970702846A (ko) | 1997-06-10 |
| DE69515465D1 (de) | 2000-04-13 |
| ES2145929T3 (es) | 2000-07-16 |
| ATE190304T1 (de) | 2000-03-15 |
| EP0738711B1 (fr) | 2000-03-08 |
| EP0738711A1 (fr) | 1996-10-23 |
| WO1996014293A1 (fr) | 1996-05-17 |
| KR100376150B1 (ko) | 2003-11-01 |
| FI962751A (fi) | 1996-07-04 |
| CA2180021A1 (fr) | 1996-05-17 |
| DE69515465T2 (de) | 2000-08-03 |
| NO962810D0 (no) | 1996-07-03 |
| NO962810L (no) | 1996-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |