NO962810D0 - Nye 1,3-dialkylureaderivater med en hydroksylgruppe - Google Patents

Nye 1,3-dialkylureaderivater med en hydroksylgruppe

Info

Publication number
NO962810D0
NO962810D0 NO962810A NO962810A NO962810D0 NO 962810 D0 NO962810 D0 NO 962810D0 NO 962810 A NO962810 A NO 962810A NO 962810 A NO962810 A NO 962810A NO 962810 D0 NO962810 D0 NO 962810D0
Authority
NO
Norway
Prior art keywords
alkyl group
lower alkyl
substituted
group
phenyl
Prior art date
Application number
NO962810A
Other languages
English (en)
Other versions
NO962810L (no
NO306944B1 (no
Inventor
Yoichi Kawashima
Ken-Ichi Fujimura
Hiroshi Suhara
Nobuaki Miyawaki
Yuko Fujita
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of NO962810L publication Critical patent/NO962810L/no
Publication of NO962810D0 publication Critical patent/NO962810D0/no
Publication of NO306944B1 publication Critical patent/NO306944B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/10Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
NO962810A 1994-11-04 1996-07-03 Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav NO306944B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27095794 1994-11-04
PCT/JP1995/002236 WO1996014293A1 (fr) 1994-11-04 1995-11-01 Nouveau derive de 1,3-dialkyluree ayant un groupe hydroxyle

Publications (3)

Publication Number Publication Date
NO962810L NO962810L (no) 1996-07-03
NO962810D0 true NO962810D0 (no) 1996-07-03
NO306944B1 NO306944B1 (no) 2000-01-17

Family

ID=17493383

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962810A NO306944B1 (no) 1994-11-04 1996-07-03 Nye 1,3-dialkylureaderivater med en hydroksylgruppe, farmasaeytisk preparat inneholdende slike derivater og anvendelse derav

Country Status (11)

Country Link
US (1) US5891912A (no)
EP (1) EP0738711B1 (no)
KR (1) KR100376150B1 (no)
CN (1) CN1055681C (no)
AT (1) ATE190304T1 (no)
CA (1) CA2180021A1 (no)
DE (1) DE69515465T2 (no)
ES (1) ES2145929T3 (no)
FI (1) FI962751A (no)
NO (1) NO306944B1 (no)
WO (1) WO1996014293A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
US5985968A (en) * 1997-11-17 1999-11-16 Air Products And Chemicals, Inc. Surface tension reduction with N,N-dialkyl ureas
US6156784A (en) * 1997-12-18 2000-12-05 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as phosphotyrosine mimics
US6677360B2 (en) * 1998-12-16 2004-01-13 Bayer Aktiengesellschaft Biphenyl and biphenyl-analogous compounds as integrin antagonists
US6420396B1 (en) 1998-12-16 2002-07-16 Beiersdorf Ag Biphenyl and biphenyl-analogous compounds as integrin antagonists
FR2820136A1 (fr) * 2001-01-26 2002-08-02 Aventis Pharma Sa Nouveaux derives de l'uree, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
US6842358B2 (en) * 2002-08-01 2005-01-11 Netlogic Microsystems, Inc. Content addressable memory with cascaded array
KR20050093759A (ko) 2002-09-18 2005-09-23 오르토-맥네일 파마슈티칼, 인코퍼레이티드 혈소판 및 조혈 줄기세포의 생산을 증가시키는 방법
DE10252650A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Cyclohexyl-Harnstoff-Derivate
US7045653B2 (en) 2002-12-23 2006-05-16 Pfizer, Inc. Pharmaceuticals
EP1615915A1 (en) * 2003-04-21 2006-01-18 Elan Pharmaceuticals, Inc. Phenacyl 2-hydroxy-3-diaminoalkanes
SG131110A1 (en) * 2003-08-28 2007-04-26 Ortho Mcneil Pharm Inc Peptides and compounds that bind to thrombopoietin receptors
WO2005063699A1 (en) * 2003-12-31 2005-07-14 Council Of Scientific & Industrial Research N-aryloxypropanolyl-n’-phenethyl-urea
US6962945B2 (en) 2004-03-26 2005-11-08 Council Of Scientific And Industrial Research N-aryloxypropanolyl-N′-phenethyl-urea
FR2885129B1 (fr) 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
CA2630860A1 (en) * 2005-11-25 2007-05-31 Galapagos Sas Urea derivatives useful as calcium receptor modulators
GB0613674D0 (en) * 2006-07-10 2006-08-16 Proskelia Sas Derivatives of urea and related diamines, methods for their manufacture, and uses therefor
JP2012526810A (ja) 2009-05-13 2012-11-01 イントラ−セルラー・セラピーズ・インコーポレイテッド 有機化合物
UY32662A (es) * 2009-05-28 2010-12-31 Novartis Ag Derivados amino-propionicos sustituidos como inhibidores de neprilisina
WO2010136474A2 (en) 2009-05-28 2010-12-02 Novartis Ag Substituted aminobutyric derivatives as neprilysin inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
WO2011136231A1 (ja) * 2010-04-30 2011-11-03 日産化学工業株式会社 ビスアミノフェニルアルキルウレアの新規な製造方法
EA026989B1 (ru) 2013-02-14 2017-06-30 Новартис Аг Производные замещенной бисфенилбутановой кислоты в качестве ингибиторов nep с улучшенной in vivo эффективностью
US9163040B2 (en) 2013-02-14 2015-10-20 Novartis Ag Substituted bisphenyl butanoic phosphonic acid derivatives as NEP inhibitors
WO2014127331A1 (en) 2013-02-17 2014-08-21 Intra-Cellular Therapies, Inc. Novel uses
WO2016022893A1 (en) 2014-08-07 2016-02-11 Intra-Cellular Therapies, Inc. Organic compounds
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
US11839614B2 (en) 2018-01-31 2023-12-12 Intra-Cellular Therapies, Inc. Methods for treating or mitigating cardiotoxicity characterized by inhibition of adenosine A2 signaling and/or adenosine A2 receptor expression

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53315B1 (en) * 1980-12-18 1988-10-12 Schering Corp Substituted dipeptides,processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
EP0054862B1 (en) * 1980-12-18 1985-11-27 Schering Corporation Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase
DE3134933A1 (de) * 1981-09-03 1983-03-31 Hoechst Ag, 6230 Frankfurt "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
JPS5823851A (ja) * 1982-07-29 1983-02-12 Mitsubishi Gas Chem Co Inc 耐熱性樹脂組成物
US4668769A (en) * 1985-08-02 1987-05-26 Hoover Dennis J Oxa- and azahomocyclostatine polypeptides
US4599198A (en) * 1985-08-02 1986-07-08 Pfizer Inc. Intermediates in polypeptide synthesis
US4757050A (en) * 1985-12-23 1988-07-12 E. R. Squibb Sons, Inc. Ureido renin inhibitors
CA1297631C (en) * 1985-12-23 1992-03-17 Sesha I. Natarajan Ureido renin inhibitors
DE3619508A1 (de) * 1986-06-10 1987-12-17 Merck Patent Gmbh Aminosaeurederivate
JP2775690B2 (ja) * 1989-08-22 1998-07-16 昭和シェル石油株式会社 スリップ・レイヤー・シート
US5475027A (en) * 1990-11-19 1995-12-12 G.D. Searle & Co. Retroviral protease inhibitors
ES2059289T3 (es) * 1990-11-19 1997-10-16 Monsanto Co Inhibidores de la proteasa retroviral.
JPH0672985A (ja) * 1992-08-28 1994-03-15 Ono Pharmaceut Co Ltd (チオ)ウレア誘導体
JP3118738B2 (ja) * 1992-12-22 2000-12-18 小野薬品工業株式会社 (チオ)ウレア誘導体

Also Published As

Publication number Publication date
CN1138321A (zh) 1996-12-18
WO1996014293A1 (fr) 1996-05-17
CN1055681C (zh) 2000-08-23
NO962810L (no) 1996-07-03
EP0738711A1 (en) 1996-10-23
US5891912A (en) 1999-04-06
KR970702846A (ko) 1997-06-10
ATE190304T1 (de) 2000-03-15
FI962751A0 (fi) 1996-07-04
NO306944B1 (no) 2000-01-17
EP0738711A4 (en) 1998-09-30
FI962751A (fi) 1996-07-04
DE69515465D1 (de) 2000-04-13
CA2180021A1 (en) 1996-05-17
DE69515465T2 (de) 2000-08-03
EP0738711B1 (en) 2000-03-08
KR100376150B1 (ko) 2003-11-01
ES2145929T3 (es) 2000-07-16

Similar Documents

Publication Publication Date Title
NO962810L (no) Nye 1,3-dialkylureaderivater med en hydroksylgruppe
LU91587I2 (fr) Agomélatine et ses dérivés pharmaceutiquement acceptables (VALDOXAN)
MX9102241A (es) Analogos de gaba y de acido l-glutamico para tratamiento contra ataques.
DK0641330T3 (da) Gaba- og L-glutaminsyreanaloger til antikrampeanfaldsbehandling
KR960703580A (ko) 눈의 염증성 질환을 치료하기 위한 3-벤조일페닐아세트산 유도체를 함유하는 국소투여가능한 조성물(Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders)
LU91943I2 (fr) Tafluprost et ses dérivés pharmaceutiquement acceptables (SAFLUTAN®)
KR950700258A (ko) 레티노이드 수용체(rar)에 결합하는 헤테로고리 탄산유도체(heterocyclic carbonic acid derivatives which bind to retinoid receptors(rar))
NO972307L (no) Matriksmetallproteaseinhibitorer
KR960010000A (ko) 종양괴사인자(tnf)생성 저해제로서의 카테콜 디에테르 화합물
EP0798291A4 (en) NEW 1,3-DIALKYL URINE DERIVATIVES
KR970707139A (ko) 평활근 세포 증식의 억제제로서의 다음이온성 벤질글리코사이드(Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation)
FI921459A0 (fi) Piperidinderivat, framstaellning av dessa samt terapeutisk anvaendning av dessa.
DK0984934T3 (da) Hidtil ukendte oralt aktive jern(III)chelateringsmidler
FI923759A (fi) Terapeutiska bensazapinfoereningar
ES8401928A1 (es) Procedimiento de obtencion de composiciones oftalmologicas.
ES8507468A1 (es) Procedimiento de obtencion de agentes de beta-bloqueantes conteniendo grupos ester con propiedades oftalmologicas
DE69123757D1 (de) Epoxysuccinamidsäurederivat
GR3007599T3 (no)
GB1139940A (en) Oxazole derivatives
SE8800846D0 (sv) Optiskt aktiva oxo-isoindolinderivat
DK0653426T3 (da) Indolderivater, salte deraf og terapeutisk middel mod hjertesygdamme, der omfatter disse
WO2000075116A3 (en) Tricyclic analgesics
JPS52111528A (en) Phenoxyphenoxyalkane carboxylic acid derivatives and herbicidal compos ition containing the same
PT78667A (en) Chemical compounds

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees