NO306619B1 - Farmasöytisk preparat inneholdende en hemmer av testosteron 5<alfa>-reduktaseaktivitet samt anvendelse av slik hemmer for fremstilling av et legemiddel - Google Patents

Farmasöytisk preparat inneholdende en hemmer av testosteron 5<alfa>-reduktaseaktivitet samt anvendelse av slik hemmer for fremstilling av et legemiddel

Info

Publication number
NO306619B1
NO306619B1 NO944458A NO944458A NO306619B1 NO 306619 B1 NO306619 B1 NO 306619B1 NO 944458 A NO944458 A NO 944458A NO 944458 A NO944458 A NO 944458A NO 306619 B1 NO306619 B1 NO 306619B1
Authority
NO
Norway
Prior art keywords
inhibitor
testosterone
alfa
medicament
manufacture
Prior art date
Application number
NO944458A
Other languages
English (en)
Other versions
NO944458D0 (no
NO944458L (no
Inventor
Fernand Labrie
Yves Merand
Shankar M Singh
Original Assignee
Endorecherche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endorecherche Inc filed Critical Endorecherche Inc
Publication of NO944458D0 publication Critical patent/NO944458D0/no
Publication of NO944458L publication Critical patent/NO944458L/no
Publication of NO306619B1 publication Critical patent/NO306619B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO944458A 1992-05-21 1994-11-21 Farmasöytisk preparat inneholdende en hemmer av testosteron 5<alfa>-reduktaseaktivitet samt anvendelse av slik hemmer for fremstilling av et legemiddel NO306619B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88696192A 1992-05-21 1992-05-21
PCT/CA1993/000192 WO1993023053A1 (en) 1992-05-21 1993-05-06 INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY

Publications (3)

Publication Number Publication Date
NO944458D0 NO944458D0 (no) 1994-11-21
NO944458L NO944458L (no) 1995-01-09
NO306619B1 true NO306619B1 (no) 1999-11-29

Family

ID=25390152

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944458A NO306619B1 (no) 1992-05-21 1994-11-21 Farmasöytisk preparat inneholdende en hemmer av testosteron 5<alfa>-reduktaseaktivitet samt anvendelse av slik hemmer for fremstilling av et legemiddel

Country Status (20)

Country Link
US (1) US5494914A (no)
EP (1) EP0641211A1 (no)
JP (1) JPH07506575A (no)
KR (1) KR950701527A (no)
AU (1) AU4258493A (no)
CA (1) CA2136304A1 (no)
CZ (1) CZ286894A3 (no)
FI (1) FI945457A (no)
HU (1) HUT71514A (no)
IL (1) IL105721A0 (no)
NO (1) NO306619B1 (no)
NZ (1) NZ247598A (no)
PH (1) PH30247A (no)
PL (1) PL175591B1 (no)
RU (1) RU2141967C1 (no)
SK (1) SK140494A3 (no)
TW (1) TW239145B (no)
UA (1) UA35589C2 (no)
WO (1) WO1993023053A1 (no)
ZA (2) ZA933441B (no)

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WO1993023039A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. Substituted 4-aza-5a-androstan-ones as 5a-reductase inhibitors
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EP0724592B1 (en) * 1993-10-21 1999-01-07 Merck & Co. Inc. 16-substituted-4-aza-androstane 5-alpha-reductase isozyme 1 inhibitors
US5817818A (en) * 1994-09-16 1998-10-06 Glaxo Wellcome Inc. Androstenones
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EP1832598A3 (en) 1999-09-30 2008-01-02 Hollis-Eden Pharmaceuticals Inc. Therapeutic treatment of androgen receptor driven conditions
US20060148725A1 (en) * 2001-12-21 2006-07-06 The Miriam Hospital Selective 11beta HSD inhibitors and methods of use thereof
EP1587574A4 (en) * 2001-12-21 2009-03-18 Rhode Island Hospital 11b-HSD SELECTIVE INHIBITORS AND METHODS OF USE
AU2003219656B2 (en) * 2002-01-15 2007-05-17 Merck Sharp & Dohme Corp. 17-hydroxy-4-aza-androstan-3-ones as androgen receptor modulators
WO2004097002A2 (en) * 2003-04-29 2004-11-11 The Miriam Hospital SELECTIVE TESTICULAR 11β-HSD INHIBITORS AND METHODS OF USE THEREOF
US7351698B2 (en) * 2003-05-07 2008-04-01 Merck & Co., Inc. Androgen receptor modulators and methods of use thereof
US7696217B2 (en) * 2003-06-30 2010-04-13 Merck Sharp & Dohme Corp. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
US7329750B2 (en) * 2003-06-30 2008-02-12 Merck & Co., Inc. 17-Acetamido-4-azasteroid derivatives as androgen receptor modulators
WO2005005606A2 (en) * 2003-06-30 2005-01-20 Merck & Co., Inc. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
US8481530B2 (en) * 2006-12-01 2013-07-09 The Research Foundation Of State University Of New York 3β-hydroxysteroid dehydrogenase inhibitors
WO2014096139A1 (en) 2012-12-20 2014-06-26 Solural Pharma ApS Solid oral dosage form of testosterone derivative
CN107073127A (zh) 2014-06-19 2017-08-18 索露奥公司 亲脂性化合物的固体口服剂型

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Also Published As

Publication number Publication date
JPH07506575A (ja) 1995-07-20
EP0641211A1 (en) 1995-03-08
US5494914A (en) 1996-02-27
CZ286894A3 (en) 1995-09-13
KR950701527A (ko) 1995-04-28
FI945457A (fi) 1995-01-16
RU94046057A (ru) 1996-10-10
FI945457A0 (fi) 1994-11-21
SK140494A3 (en) 1995-07-11
ZA933545B (en) 1994-11-21
AU4258493A (en) 1993-12-13
HUT71514A (en) 1995-12-28
PH30247A (en) 1997-02-05
ZA933441B (en) 1994-11-18
PL175591B1 (pl) 1999-01-29
CA2136304A1 (en) 1993-11-25
NO944458D0 (no) 1994-11-21
RU2141967C1 (ru) 1999-11-27
WO1993023053A1 (en) 1993-11-25
TW239145B (no) 1995-01-21
NO944458L (no) 1995-01-09
UA35589C2 (uk) 2001-04-16
NZ247598A (en) 1995-12-21
IL105721A0 (en) 1993-09-22

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