IL105721A0 - Inhibitors of testosterone 5 alpha-reductase activity - Google Patents

Inhibitors of testosterone 5 alpha-reductase activity

Info

Publication number
IL105721A0
IL105721A0 IL105721A IL10572193A IL105721A0 IL 105721 A0 IL105721 A0 IL 105721A0 IL 105721 A IL105721 A IL 105721A IL 10572193 A IL10572193 A IL 10572193A IL 105721 A0 IL105721 A0 IL 105721A0
Authority
IL
Israel
Prior art keywords
testosterone
inhibitors
alpha
reductase activity
reductase
Prior art date
Application number
IL105721A
Other languages
English (en)
Original Assignee
Endorecherche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endorecherche Inc filed Critical Endorecherche Inc
Publication of IL105721A0 publication Critical patent/IL105721A0/xx
Priority to IL12913299A priority Critical patent/IL129132A0/xx
Priority to IL12913199A priority patent/IL129131A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL105721A 1992-05-21 1993-05-17 Inhibitors of testosterone 5 alpha-reductase activity IL105721A0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL12913299A IL129132A0 (en) 1993-05-17 1999-03-23 Inhibitors of testosterone 5-alpha reductase activity
IL12913199A IL129131A0 (en) 1993-05-17 1999-03-23 Inhibitors of testosterone 5- alpha-reductase activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88696192A 1992-05-21 1992-05-21

Publications (1)

Publication Number Publication Date
IL105721A0 true IL105721A0 (en) 1993-09-22

Family

ID=25390152

Family Applications (1)

Application Number Title Priority Date Filing Date
IL105721A IL105721A0 (en) 1992-05-21 1993-05-17 Inhibitors of testosterone 5 alpha-reductase activity

Country Status (20)

Country Link
US (1) US5494914A (xx)
EP (1) EP0641211A1 (xx)
JP (1) JPH07506575A (xx)
KR (1) KR950701527A (xx)
AU (1) AU4258493A (xx)
CA (1) CA2136304A1 (xx)
CZ (1) CZ286894A3 (xx)
FI (1) FI945457A (xx)
HU (1) HUT71514A (xx)
IL (1) IL105721A0 (xx)
NO (1) NO306619B1 (xx)
NZ (1) NZ247598A (xx)
PH (1) PH30247A (xx)
PL (1) PL175591B1 (xx)
RU (1) RU2141967C1 (xx)
SK (1) SK140494A3 (xx)
TW (1) TW239145B (xx)
UA (1) UA35589C2 (xx)
WO (1) WO1993023053A1 (xx)
ZA (2) ZA933441B (xx)

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WO1993023039A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. Substituted 4-aza-5a-androstan-ones as 5a-reductase inhibitors
DE69329149T2 (de) * 1992-05-20 2001-03-29 Merck & Co Inc 4-azasteroide als 5-alpha-reduktase
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US5739137A (en) * 1993-10-21 1998-04-14 Merck & Co., Inc. 16-substituted-4-aza-3-oxo-androstane as 5-alpha-reductase isozyme 1 inhibitors
US5817818A (en) * 1994-09-16 1998-10-06 Glaxo Wellcome Inc. Androstenones
US5541322A (en) * 1994-10-14 1996-07-30 Glaxo Wellcome Inc. Synthesis of 6-azaandrostenones
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AU2002361861A1 (en) * 2001-12-21 2003-07-30 Rhode Island Hospital SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF
US20060148725A1 (en) * 2001-12-21 2006-07-06 The Miriam Hospital Selective 11beta HSD inhibitors and methods of use thereof
CA2472475C (en) * 2002-01-15 2010-05-18 Merck & Co., Inc. 17-hydroxy-4-aza-androstan-3-ones as androgen receptor modulators
WO2004097002A2 (en) * 2003-04-29 2004-11-11 The Miriam Hospital SELECTIVE TESTICULAR 11β-HSD INHIBITORS AND METHODS OF USE THEREOF
WO2004100874A2 (en) * 2003-05-07 2004-11-25 Merck & Co., Inc. Androgen receptor modulators and methods of use thereof
AU2004259664B2 (en) * 2003-06-30 2009-05-28 Merck Sharp & Dohme Corp. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
JP2007521292A (ja) * 2003-06-30 2007-08-02 メルク　エンド　カムパニー　インコーポレーテッド アンドロゲン受容体モジュレータとしての１７−アセトアミド−４−アザステロイド誘導体
AU2004256075B2 (en) * 2003-06-30 2008-12-04 Merck Sharp & Dohme Corp. 17-acetamido-4-azasteroid derivatives as androgen receptor modulators
WO2008070039A2 (en) * 2006-12-01 2008-06-12 The Research Foundation Of State University Of New York 3 beta-hydroxysteroid dehydrogenase inhibitors
MX360186B (es) 2012-12-20 2018-10-24 Solural Pharma ApS Forma de dosificacion oral solida de derivado de testosterona.
EA036836B1 (ru) 2014-06-19 2020-12-25 Солурал Фарма Апс Фармацевтическая композиция для обеспечения лимфатической абсорбции липофильных соединений после еды и натощак

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Also Published As

Publication number Publication date
AU4258493A (en) 1993-12-13
RU94046057A (ru) 1996-10-10
WO1993023053A1 (en) 1993-11-25
NO306619B1 (no) 1999-11-29
CA2136304A1 (en) 1993-11-25
JPH07506575A (ja) 1995-07-20
ZA933545B (en) 1994-11-21
NO944458D0 (no) 1994-11-21
ZA933441B (en) 1994-11-18
PL175591B1 (pl) 1999-01-29
UA35589C2 (uk) 2001-04-16
CZ286894A3 (en) 1995-09-13
RU2141967C1 (ru) 1999-11-27
NO944458L (no) 1995-01-09
EP0641211A1 (en) 1995-03-08
FI945457A0 (fi) 1994-11-21
NZ247598A (en) 1995-12-21
TW239145B (xx) 1995-01-21
FI945457A (fi) 1995-01-16
US5494914A (en) 1996-02-27
KR950701527A (ko) 1995-04-28
PH30247A (en) 1997-02-05
HUT71514A (en) 1995-12-28
SK140494A3 (en) 1995-07-11

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