NO305751B1 - Substituerte benzensulfonylurinstoffer og -tiourinstoffer, deres anvendelse for fremstilling av medikament eller diagnostikum, sÕvel som legemidler inneholdende forbindelsene - Google Patents
Substituerte benzensulfonylurinstoffer og -tiourinstoffer, deres anvendelse for fremstilling av medikament eller diagnostikum, sÕvel som legemidler inneholdende forbindelseneInfo
- Publication number
- NO305751B1 NO305751B1 NO960627A NO960627A NO305751B1 NO 305751 B1 NO305751 B1 NO 305751B1 NO 960627 A NO960627 A NO 960627A NO 960627 A NO960627 A NO 960627A NO 305751 B1 NO305751 B1 NO 305751B1
- Authority
- NO
- Norway
- Prior art keywords
- drugs
- thioureas
- diagnostics
- compounds
- manufacture
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 2
- 229940079593 drug Drugs 0.000 title 2
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003585 thioureas Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- BVAPOGMQIPODIW-UHFFFAOYSA-N benzene;sulfonylurea Chemical compound C1=CC=CC=C1.NC(=O)N=S(=O)=O BVAPOGMQIPODIW-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19505397A DE19505397A1 (de) | 1995-02-17 | 1995-02-17 | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO960627D0 NO960627D0 (no) | 1996-02-16 |
| NO960627L NO960627L (no) | 1996-08-19 |
| NO305751B1 true NO305751B1 (no) | 1999-07-19 |
Family
ID=7754249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO960627A NO305751B1 (no) | 1995-02-17 | 1996-02-16 | Substituerte benzensulfonylurinstoffer og -tiourinstoffer, deres anvendelse for fremstilling av medikament eller diagnostikum, sÕvel som legemidler inneholdende forbindelsene |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US5652268A (cs) |
| EP (1) | EP0727416B1 (cs) |
| JP (1) | JP3905568B2 (cs) |
| KR (1) | KR100450914B1 (cs) |
| CN (1) | CN1058705C (cs) |
| AR (1) | AR003924A1 (cs) |
| AT (1) | ATE189213T1 (cs) |
| AU (1) | AU700793B2 (cs) |
| BR (1) | BR9600778A (cs) |
| CA (1) | CA2169694C (cs) |
| CY (1) | CY2220B1 (cs) |
| CZ (1) | CZ291271B6 (cs) |
| DE (2) | DE19505397A1 (cs) |
| DK (1) | DK0727416T3 (cs) |
| ES (1) | ES2143675T3 (cs) |
| FI (1) | FI120393B (cs) |
| GR (1) | GR3033049T3 (cs) |
| HR (1) | HRP960077B1 (cs) |
| HU (1) | HU226463B1 (cs) |
| IL (1) | IL117150A (cs) |
| MY (1) | MY113431A (cs) |
| NO (1) | NO305751B1 (cs) |
| NZ (1) | NZ280991A (cs) |
| PL (1) | PL181950B1 (cs) |
| PT (1) | PT727416E (cs) |
| RU (1) | RU2198163C2 (cs) |
| SI (1) | SI9600049B (cs) |
| SK (1) | SK281605B6 (cs) |
| TR (1) | TR199600118A2 (cs) |
| TW (1) | TW355183B (cs) |
| ZA (1) | ZA961231B (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
| DE19647000A1 (de) * | 1996-11-14 | 1998-05-20 | Hoechst Ag | 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE19832009A1 (de) | 1998-07-16 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate |
| CN1195524C (zh) * | 1998-09-10 | 2005-04-06 | 阿文蒂斯药物德国有限公司 | 苯磺酰(硫)脲与β－受体阻滞剂联合在制备用于心脏迷走神经机能障碍治疗和预防的药物中的用途 |
| DE19917233A1 (de) * | 1999-04-16 | 2000-10-19 | Aventis Pharma Gmbh | Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids |
| DE19923086A1 (de) | 1999-05-20 | 2000-11-23 | Aventis Pharma Gmbh | Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE10054482A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE10054481A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE10129704A1 (de) * | 2001-06-22 | 2003-01-02 | Aventis Pharma Gmbh | Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks |
| DE102004061017A1 (de) * | 2004-12-18 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| PT2164825E (pt) * | 2007-06-05 | 2014-06-24 | Sanofi Sa | Derivados de di(hetero)arilciclo-hexano, sua preparação, sua utilização e composições farmacêuticas compreendendo os mesmos |
| US20250145564A1 (en) * | 2021-08-16 | 2025-05-08 | Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences | Sulfonylurea compound, preparation method therefor, and application thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1198354B (de) * | 1963-09-25 | 1965-08-12 | Hoechst Ag | Verfahren zur Herstellung von Benzol-sulfonylharnstoffen |
| DE1518874C3 (de) * | 1964-10-07 | 1975-03-13 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung |
| BE754454A (fr) * | 1969-08-06 | 1971-02-05 | Bayer Ag | Nouveaux composes hypoglycemiques du type d'arylsulfonylurees et d'arylsulfonylsemicarbazides contenant des groupes carbonamide |
| DE2413514C3 (de) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
| US4927453A (en) * | 1986-10-17 | 1990-05-22 | E. I. Du Pont De Nemours And Company | Herbicidal sulfonamides |
| EP0612724B1 (de) * | 1993-02-23 | 1996-12-27 | Hoechst Aktiengesellschaft | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe- Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika |
-
1995
- 1995-02-17 DE DE19505397A patent/DE19505397A1/de not_active Withdrawn
- 1995-12-28 HU HU9503879A patent/HU226463B1/hu not_active IP Right Cessation
-
1996
- 1996-01-29 PL PL96312528A patent/PL181950B1/pl not_active IP Right Cessation
- 1996-02-12 AT AT96101976T patent/ATE189213T1/de active
- 1996-02-12 EP EP96101976A patent/EP0727416B1/de not_active Expired - Lifetime
- 1996-02-12 DE DE59604262T patent/DE59604262D1/de not_active Expired - Lifetime
- 1996-02-12 ES ES96101976T patent/ES2143675T3/es not_active Expired - Lifetime
- 1996-02-12 TW TW085101695A patent/TW355183B/zh not_active IP Right Cessation
- 1996-02-12 PT PT96101976T patent/PT727416E/pt unknown
- 1996-02-12 DK DK96101976T patent/DK0727416T3/da active
- 1996-02-14 CN CN96102016A patent/CN1058705C/zh not_active Expired - Fee Related
- 1996-02-14 CZ CZ1996436A patent/CZ291271B6/cs not_active IP Right Cessation
- 1996-02-15 SK SK211-96A patent/SK281605B6/sk not_active IP Right Cessation
- 1996-02-15 FI FI960689A patent/FI120393B/fi not_active IP Right Cessation
- 1996-02-15 AU AU45560/96A patent/AU700793B2/en not_active Ceased
- 1996-02-15 AR ARP960101392A patent/AR003924A1/es unknown
- 1996-02-15 NZ NZ280991A patent/NZ280991A/en not_active IP Right Cessation
- 1996-02-15 TR TR96/00118A patent/TR199600118A2/xx unknown
- 1996-02-15 HR HR960077A patent/HRP960077B1/xx not_active IP Right Cessation
- 1996-02-15 US US08/602,053 patent/US5652268A/en not_active Expired - Lifetime
- 1996-02-15 IL IL11715096A patent/IL117150A/xx not_active IP Right Cessation
- 1996-02-16 RU RU96102869/04A patent/RU2198163C2/ru not_active IP Right Cessation
- 1996-02-16 JP JP02905396A patent/JP3905568B2/ja not_active Expired - Fee Related
- 1996-02-16 BR BR9600778A patent/BR9600778A/pt not_active Application Discontinuation
- 1996-02-16 ZA ZA961231A patent/ZA961231B/xx unknown
- 1996-02-16 NO NO960627A patent/NO305751B1/no not_active IP Right Cessation
- 1996-02-16 MY MYPI96000623A patent/MY113431A/en unknown
- 1996-02-16 CA CA002169694A patent/CA2169694C/en not_active Expired - Fee Related
- 1996-02-16 SI SI9600049A patent/SI9600049B/sl not_active IP Right Cessation
- 1996-02-16 KR KR1019960003824A patent/KR100450914B1/ko not_active Expired - Fee Related
-
2000
- 2000-03-24 GR GR20000400736T patent/GR3033049T3/el unknown
-
2001
- 2001-05-03 CY CY0100006A patent/CY2220B1/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |