NO302236B1 - Analogifremgangsmåte til fremstilling av antibakterielle penemesterderivater - Google Patents

Analogifremgangsmåte til fremstilling av antibakterielle penemesterderivater

Info

Publication number
NO302236B1
NO302236B1 NO930588A NO930588A NO302236B1 NO 302236 B1 NO302236 B1 NO 302236B1 NO 930588 A NO930588 A NO 930588A NO 930588 A NO930588 A NO 930588A NO 302236 B1 NO302236 B1 NO 302236B1
Authority
NO
Norway
Prior art keywords
group
antibacterial
penemester
derivatives
preparation
Prior art date
Application number
NO930588A
Other languages
English (en)
Norwegian (no)
Other versions
NO930588D0 (no
NO930588L (no
Inventor
Hiromitsu Iwata
Takashi Nakatsuka
Rie Tanaka
Masaji Ishiguro
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Publication of NO930588D0 publication Critical patent/NO930588D0/no
Publication of NO930588L publication Critical patent/NO930588L/no
Publication of NO302236B1 publication Critical patent/NO302236B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/861—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrocarbon radical or a substituted hydrocarbon radical, directly attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/893—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero ring or a condensed hetero ring system, directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO930588A 1990-08-20 1993-02-19 Analogifremgangsmåte til fremstilling av antibakterielle penemesterderivater NO302236B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21705290 1990-08-20
PCT/JP1991/001098 WO1992003442A1 (en) 1990-08-20 1991-08-16 Antibacterial penem esters derivatives

Publications (3)

Publication Number Publication Date
NO930588D0 NO930588D0 (no) 1993-02-19
NO930588L NO930588L (no) 1993-02-19
NO302236B1 true NO302236B1 (no) 1998-02-09

Family

ID=16698076

Family Applications (1)

Application Number Title Priority Date Filing Date
NO930588A NO302236B1 (no) 1990-08-20 1993-02-19 Analogifremgangsmåte til fremstilling av antibakterielle penemesterderivater

Country Status (23)

Country Link
US (2) US5830889A (de)
EP (2) EP0757050B1 (de)
JP (2) JP3148234B2 (de)
KR (1) KR0178956B1 (de)
AT (2) ATE242251T1 (de)
AU (1) AU652954B2 (de)
BR (1) BR9106789A (de)
CA (1) CA2089368C (de)
CZ (1) CZ282086B6 (de)
DE (2) DE69131753T2 (de)
DK (1) DK0544907T3 (de)
ES (2) ES2137929T3 (de)
FI (1) FI105186B (de)
GR (1) GR3032372T3 (de)
HU (1) HU213403B (de)
IE (1) IE20000929A1 (de)
IL (1) IL99243A (de)
MX (1) MX9203822A (de)
NO (1) NO302236B1 (de)
PL (1) PL169584B1 (de)
RU (1) RU2051919C1 (de)
SK (1) SK280188B6 (de)
WO (1) WO1992003442A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE283707T1 (de) * 1998-01-13 2004-12-15 Daiichi Suntory Pharma Co Ltd Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem
EP1191948A2 (de) * 1999-06-11 2002-04-03 Neorx Corporation Hochdosierte radionuklide komplexe zur knochenmark-unterdrückung
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
JP2004536034A (ja) * 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
JP2005516933A (ja) 2001-12-13 2005-06-09 ダウ グローバル テクノロジーズ インコーポレイティド 放射性医薬による骨髄炎の治療
CA2500330C (en) * 2002-10-02 2008-08-12 Nippon Soda Co., Ltd. Processes for preparation of organic compounds
CN1314691C (zh) * 2005-08-22 2007-05-09 鲁南制药集团股份有限公司 法罗培南钠的制备方法
US7977475B2 (en) * 2005-10-05 2011-07-12 Ranbaxy Laboratories Limited Process for the preparation of faropenem
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug
CN101235044B (zh) * 2008-03-03 2010-11-03 南京华威医药科技开发有限公司 法罗培南酯的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019908B2 (ja) * 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
CA1212105A (en) * 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
US4479947A (en) * 1981-07-13 1984-10-30 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
US4654331A (en) * 1981-07-13 1987-03-31 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
JPS58159496A (ja) * 1983-03-02 1983-09-21 Kyoto Yakuhin Kogyo Kk セフエム系化合物
JPH075463B2 (ja) * 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
EP0275002A1 (de) * 1987-01-09 1988-07-20 Hoechst Aktiengesellschaft Verfahren zur Herstellung von 7-Oxo-4-thia-1-aza-bicyclo[3.2.0]-hept-2-en-Derivaten
GB8713515D0 (en) * 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
JPH026728A (ja) 1988-06-23 1990-01-10 Japan Radio Co Ltd 弾性表面波による液体粘性測定装置
GB2220203B (en) * 1988-07-04 1991-09-11 Erba Carlo Spa Process for penems
DE3839987A1 (de) * 1988-11-26 1990-05-31 Hoechst Ag Penemderivate und verfahren zu ihrer herstellung
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen

Also Published As

Publication number Publication date
ES2198455T3 (es) 2004-02-01
CA2089368C (en) 2002-08-06
DE69131753D1 (de) 1999-12-02
IE20000929A1 (en) 2001-05-30
NO930588D0 (no) 1993-02-19
DE69133273T2 (de) 2004-05-13
JP3148234B2 (ja) 2001-03-19
HUT64349A (en) 1993-12-28
KR0178956B1 (ko) 1999-03-20
AU652954B2 (en) 1994-09-15
CA2089368A1 (en) 1992-02-21
US5830889A (en) 1998-11-03
DK0544907T3 (da) 2000-01-24
MX9203822A (es) 1992-09-01
NO930588L (no) 1993-02-19
CZ20993A3 (en) 1993-10-13
JP3274854B2 (ja) 2002-04-15
SK10793A3 (en) 1993-09-09
ES2137929T3 (es) 2000-01-01
DE69133273D1 (de) 2003-07-10
KR930701452A (ko) 1993-06-11
EP0757050A1 (de) 1997-02-05
FI930682A (fi) 1993-02-16
ATE242251T1 (de) 2003-06-15
EP0544907B1 (de) 1999-10-27
US5885981A (en) 1999-03-23
IL99243A0 (en) 1992-07-15
SK280188B6 (sk) 1999-09-10
IL99243A (en) 1995-07-31
EP0757050B1 (de) 2003-06-04
FI105186B (fi) 2000-06-30
JPH06500769A (ja) 1994-01-27
HU213403B (en) 1997-06-30
FI930682A0 (fi) 1993-02-16
GR3032372T3 (en) 2000-04-27
RU2051919C1 (ru) 1996-01-10
DE69131753T2 (de) 2000-05-04
BR9106789A (pt) 1993-06-29
ATE186053T1 (de) 1999-11-15
PL169584B1 (pl) 1996-08-30
EP0544907A1 (de) 1993-06-09
WO1992003442A1 (en) 1992-03-05
AU8333391A (en) 1992-03-17
JP2000302786A (ja) 2000-10-31
CZ282086B6 (cs) 1997-05-14
HU9300461D0 (en) 1993-05-28

Similar Documents

Publication Publication Date Title
NO302236B1 (no) Analogifremgangsmåte til fremstilling av antibakterielle penemesterderivater
NO970385L (no) Analogifremgangsmåte for fremstilling av et terapautisk aktivt nukleosid
FI932031A (fi) System och foerfarande foer behandling av biologiska vaetskor
YU39431B (en) Process for the manufacture of 13-halo and 13-deoxy derivatives of compounds of the macrolide series, isolated from the fermentation broth of streptomyces avermilitis
NO893704D0 (no) Fremgangsmaate ved kontroll av avsetning paa papirmaskinfilter o.l.
IE791661L (en) Penam compounds
ES552509A0 (es) Procedimiento de preparacion de esteres heterociclicos disimetricos de acidos 1,4-dihidropiridina-3,5-dicarboxilicos.
IE780638L (en) B-lactam antibiotic.
FI873290A (fi) Foerfarande foer syntetisering av penem.
NL180317C (nl) Werkwijze voor het bereiden van penicillaanzuur-1,1-dioxyde en esters daarvan en van farmaceutisch aanvaardbare zouten van het penicillaanzuur-1,1-dioxyde.
CA2038435A1 (en) Process for preparation of fluoromethyl-substituted piperidine carbodithioates
GR3017814T3 (en) Herbicidal 2-(2-imidazolin -2-yl)-benzazoles.
FI913280A (fi) Mikrobiologiskt foerfarande foer oxidering av metylgrupper.
IE852246L (en) Penicillins
IE802112L (en) Pyridine derivatives.
NO174666C (no) Fremgangsmåte ved fremstilling av en optisk aktiv, höyredreiende oksoiso-indolinylforbindelse
SE7706190L (sv) Sett att framstella derivat av rifamycin p och q
JPS55154603A (en) Control unit for instrument
ATE111092T1 (de) Antibiotikum a80915 und verfahren zu seiner herstellung.
ATE63538T1 (de) Herstellung von 9-alkenylesterverbindungen.
DK0460881T3 (da) Fremgangsmåde til fremstilling af bicycliske beta-lactamer
SU602541A1 (ru) Способ автоматического управлени процессом выращивани микроорганизмов
NO951030D0 (no) Fremgangsmåte for stereoselektiv fremstilling av et derivat av v taxanderivater
NO974994L (no) Estere av karbapenemer
AU553765B2 (en) Biologically active heterocyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees