NO302031B1 - Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det - Google Patents

Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det Download PDF

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Publication number
NO302031B1
NO302031B1 NO904806A NO904806A NO302031B1 NO 302031 B1 NO302031 B1 NO 302031B1 NO 904806 A NO904806 A NO 904806A NO 904806 A NO904806 A NO 904806A NO 302031 B1 NO302031 B1 NO 302031B1
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NO
Norway
Prior art keywords
flagellin
recombinant
epitope
gene
protein
Prior art date
Application number
NO904806A
Other languages
English (en)
Norwegian (no)
Other versions
NO904806D0 (no
NO904806L (no
Inventor
William Robert Majarian
Bruce Arnold Dunbar Stocker
Salete Maria Cardozo Newton
Original Assignee
American Cyanamid Co
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co, Univ Leland Stanford Junior filed Critical American Cyanamid Co
Publication of NO904806D0 publication Critical patent/NO904806D0/no
Publication of NO904806L publication Critical patent/NO904806L/no
Publication of NO302031B1 publication Critical patent/NO302031B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO904806A 1988-05-05 1990-11-05 Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det NO302031B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19057088A 1988-05-05 1988-05-05
PCT/US1989/001932 WO1989010967A1 (en) 1988-05-05 1989-05-05 Recombinant flagellin vaccines

Publications (3)

Publication Number Publication Date
NO904806D0 NO904806D0 (no) 1990-11-05
NO904806L NO904806L (no) 1991-01-03
NO302031B1 true NO302031B1 (no) 1998-01-12

Family

ID=22701885

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904806A NO302031B1 (no) 1988-05-05 1990-11-05 Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det

Country Status (10)

Country Link
EP (1) EP0419513B1 (de)
JP (1) JP2793673B2 (de)
AT (1) ATE121782T1 (de)
AU (1) AU637049B2 (de)
CA (1) CA1340817C (de)
DE (1) DE68922394T2 (de)
DK (1) DK263390A (de)
FI (1) FI104638B (de)
NO (1) NO302031B1 (de)
WO (1) WO1989010967A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US5698390A (en) * 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
EP0449958B9 (de) * 1988-12-19 2003-05-28 American Cyanamid Company Meningococcales klasse i-aussenmembranprotein-vakzin
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
JPH06501934A (ja) * 1990-10-01 1994-03-03 イギリス国 サルモネラのテスト法
DE69126786T2 (de) * 1990-10-01 1998-01-08 The Minister Of Agriculture Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain, London Polynukleotidsequenz von salmonella
GB9101550D0 (en) * 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
IL101639A0 (en) * 1992-04-17 1992-12-30 Yeda Res & Dev Recombinant influenza vaccines
ATE269104T1 (de) * 1999-12-28 2004-07-15 Akzo Nobel Nv Salmonella impfstoff, der keinen antikörper gegen flagellin oder gegen flagella induziert
AU2002359984A1 (en) * 2002-12-16 2004-07-09 Caf Laboratories Inc. Salmonella antigen formulation and antibody test kit and subunit vaccine using the same
US20080248068A1 (en) 2004-05-07 2008-10-09 Hans-Gustaf Ljunggren Use of Flagellin as an Adjuvant for Vaccine
ATE518881T1 (de) * 2004-12-02 2011-08-15 Csir Grampositive bakterienzellen enthaltend ein unterbrochenes flagellingen, fusionsproteine auf flagellinbasis und deren verwendung zum entfernen von metallionen aus einer flüssigkeit
EP1824510B1 (de) 2004-12-16 2012-10-31 Wake Forest University Health Sciences Verwendung von flagellin bei der immuntherapie von yersinia pestis
EP1841785A2 (de) * 2005-01-19 2007-10-10 Vaxinnate Corporation Zusammensetzungen, die pathogen-assoziierte molekulare muster und antigene enthalten und deren verwendung zur stimulation des immunsystems
EP2476432B1 (de) 2006-03-07 2015-08-19 Vaxinnate Corporation Zusammensetzungen mit Hämagglutinin, Verfahren zu ihrer Herstellung und Verfahren zu ihrer Verwendung
ES2594102T3 (es) 2008-04-18 2016-12-15 Vaxinnate Corporation Mutantes por deleción de la flagelina y métodos para su uso
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
CN102816246B (zh) * 2012-09-04 2014-07-23 成都蓉生药业有限责任公司 一种人巨细胞病毒免疫原融合蛋白及其制备方法和用途
AU2015323736B2 (en) 2014-09-26 2020-09-10 Bavarian Nordic A/S Methods and compositions for intra-nasal immunization with recombinant MVA encoding flagellin
EP3221464B1 (de) * 2014-11-18 2022-02-23 The Trustees of Columbia University in the City of New York Detektion von analyten unter verwendung von lebenden zellen
CN104402974B (zh) * 2014-12-10 2017-11-14 重庆医科大学 一种具有粘膜免疫佐剂活性的多肽及其在制备粘膜免疫佐剂中的用途
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
EP0241546A4 (de) * 1985-10-11 1988-11-02 Genetics Inst Verfahren zur herstellung heterologer proteine.
ES2060580T3 (es) * 1986-03-11 1994-12-01 Shionogi & Co Adn que tiene una secuencia adn codificante de la proteina flagelina y vector que la contiene.
CA1331355C (en) * 1986-04-21 1994-08-09 Bioenterprises Pty. Ltd Immunopotentation

Also Published As

Publication number Publication date
DK263390A (da) 1991-01-04
DK263390D0 (da) 1990-11-02
NO904806D0 (no) 1990-11-05
EP0419513A1 (de) 1991-04-03
DE68922394D1 (de) 1995-06-01
ATE121782T1 (de) 1995-05-15
DE68922394T2 (de) 1995-10-05
JP2793673B2 (ja) 1998-09-03
AU3697989A (en) 1989-11-29
WO1989010967A1 (en) 1989-11-16
JPH04502402A (ja) 1992-05-07
FI104638B (fi) 2000-03-15
FI905441A0 (fi) 1990-11-02
AU637049B2 (en) 1993-05-20
EP0419513B1 (de) 1995-04-26
CA1340817C (en) 1999-11-09
NO904806L (no) 1991-01-03

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