NO300592B1 - Imidazopyridin PAF/H1 antagonister - Google Patents

Imidazopyridin PAF/H1 antagonister Download PDF

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Publication number
NO300592B1
NO300592B1 NO932889A NO932889A NO300592B1 NO 300592 B1 NO300592 B1 NO 300592B1 NO 932889 A NO932889 A NO 932889A NO 932889 A NO932889 A NO 932889A NO 300592 B1 NO300592 B1 NO 300592B1
Authority
NO
Norway
Prior art keywords
pyrid
methylimidazo
ylidene
piperidine
dihydro
Prior art date
Application number
NO932889A
Other languages
English (en)
Norwegian (no)
Other versions
NO932889L (no
NO932889D0 (no
Inventor
David Alker
Robert John Bass
Kelvin Cooper
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO932889L publication Critical patent/NO932889L/no
Publication of NO932889D0 publication Critical patent/NO932889D0/no
Publication of NO300592B1 publication Critical patent/NO300592B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
NO932889A 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister NO300592B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents
PCT/EP1992/000163 WO1992014734A1 (en) 1991-02-13 1992-01-24 Imidazopyridine paf/h1 antagonists

Publications (3)

Publication Number Publication Date
NO932889L NO932889L (no) 1993-08-13
NO932889D0 NO932889D0 (no) 1993-08-13
NO300592B1 true NO300592B1 (no) 1997-06-23

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932889A NO300592B1 (no) 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister

Country Status (29)

Country Link
US (1) US5358953A (de)
EP (1) EP0572425B1 (de)
JP (1) JP2506541B2 (de)
KR (1) KR970005302B1 (de)
CN (1) CN1040326C (de)
AT (1) ATE109482T1 (de)
AU (1) AU650322B2 (de)
BR (1) BR9205615A (de)
CA (1) CA2099381C (de)
CZ (1) CZ280504B6 (de)
DE (1) DE69200304T2 (de)
DK (1) DK0572425T3 (de)
EG (1) EG20085A (de)
ES (1) ES2059212T3 (de)
FI (1) FI933531A0 (de)
GB (1) GB9102997D0 (de)
HU (2) HUT65947A (de)
IE (1) IE65125B1 (de)
IL (1) IL100887A (de)
MX (1) MX9200589A (de)
MY (1) MY108437A (de)
NO (1) NO300592B1 (de)
NZ (1) NZ241597A (de)
PL (1) PL169304B1 (de)
RU (1) RU2114845C1 (de)
TW (1) TW227000B (de)
WO (1) WO1992014734A1 (de)
YU (1) YU48238B (de)
ZA (1) ZA921005B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
WO1996005201A1 (en) * 1994-08-10 1996-02-22 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
AU698487B2 (en) * 1995-08-05 1998-10-29 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives
ES2381775T3 (es) 2000-08-04 2012-05-31 Dmi Biosciences, Inc. Procedimiento del uso de dicetopiperazinas y composición que las contiene
AU2004241101B2 (en) 2003-05-15 2010-05-13 Ampio Pharmaceuticals, Inc. Treatment of T-cell mediated diseases
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
ES2527588T3 (es) 2008-01-30 2015-01-27 Nippon Zoki Pharmaceutical Co., Ltd. Derivado de piperidina
US8217047B2 (en) 2008-05-27 2012-07-10 Dmi Acquisition Corp. Therapeutic methods and compounds
CN103619839B (zh) * 2011-06-28 2016-06-01 福建省闽东力捷迅药业有限公司 抗-变态反应的苯并环庚并噻吩衍生物
JP2014530063A (ja) 2011-10-10 2014-11-17 アンピオ ファーマシューティカルズ,インコーポレイテッド 免疫寛容が高められた埋込み型医療用デバイス、ならびに製造方法および埋込み方法
WO2013055734A1 (en) 2011-10-10 2013-04-18 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
AU2012328605B9 (en) * 2011-10-28 2017-08-03 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
SG11201506267XA (en) 2013-03-15 2015-09-29 Ampio Pharmaceuticals Inc Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
CA2958080A1 (en) 2014-08-18 2016-02-25 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (de) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. Verwendung von niedermolekularen fraktionen von humanem serumalbumin bei der behandlung von erkrankungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68920998T2 (de) * 1988-03-15 1995-06-22 Searle & Co 1H/3H-[4-(N,N-CYCLOALKYL UND/ODER VERZWEIGTES ALKYLCARBOXAMIDO)-BENZYL]IMDAZO[4,5-c]PYRIDINE ALS PAF-ANTAGONISTEN.
MY106964A (en) * 1988-04-28 1995-08-30 Schering Corp Fused polycyclic compounds, compositions, methods of manufacture, and their use as paf antagonists, antihistamines and/or antiinflammatory agents.
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
CA2080476A1 (en) * 1990-05-09 1991-11-10 Anthony Marfat Azabenzimidazoles in the treatment of asthma, arthritis and related diseases

Also Published As

Publication number Publication date
FI933531A (fi) 1993-08-10
FI933531A0 (fi) 1993-08-10
EG20085A (en) 1997-05-31
YU48238B (sh) 1997-08-22
IL100887A0 (en) 1992-11-15
AU650322B2 (en) 1994-06-16
KR970005302B1 (ko) 1997-04-15
HU211202A9 (en) 1995-11-28
AU1168392A (en) 1992-09-15
NO932889L (no) 1993-08-13
DE69200304D1 (de) 1994-09-08
CA2099381A1 (en) 1992-08-14
WO1992014734A1 (en) 1992-09-03
TW227000B (de) 1994-07-21
CA2099381C (en) 1996-07-09
IL100887A (en) 1996-01-19
CZ280504B6 (cs) 1996-02-14
YU14392A (sh) 1994-11-15
MX9200589A (es) 1992-10-01
JP2506541B2 (ja) 1996-06-12
ATE109482T1 (de) 1994-08-15
ZA921005B (en) 1993-08-12
JPH06504992A (ja) 1994-06-09
HUT65947A (en) 1994-08-29
DE69200304T2 (de) 1994-12-08
BR9205615A (pt) 1994-05-17
EP0572425B1 (de) 1994-08-03
IE920449A1 (en) 1992-08-12
NO932889D0 (no) 1993-08-13
CN1040326C (zh) 1998-10-21
US5358953A (en) 1994-10-25
HU9302327D0 (en) 1993-10-28
RU2114845C1 (ru) 1998-07-10
IE65125B1 (en) 1995-10-04
CN1064275A (zh) 1992-09-09
MY108437A (en) 1996-09-30
CS42592A3 (en) 1992-09-16
NZ241597A (en) 1993-04-28
DK0572425T3 (da) 1994-09-12
EP0572425A1 (de) 1993-12-08
ES2059212T3 (es) 1994-11-01
GB9102997D0 (en) 1991-03-27
PL169304B1 (pl) 1996-06-28

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