NO300592B1 - Imidazopyridin PAF/H1 antagonister - Google Patents

Imidazopyridin PAF/H1 antagonister Download PDF

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Publication number
NO300592B1
NO300592B1 NO932889A NO932889A NO300592B1 NO 300592 B1 NO300592 B1 NO 300592B1 NO 932889 A NO932889 A NO 932889A NO 932889 A NO932889 A NO 932889A NO 300592 B1 NO300592 B1 NO 300592B1
Authority
NO
Norway
Prior art keywords
pyrid
methylimidazo
ylidene
piperidine
dihydro
Prior art date
Application number
NO932889A
Other languages
English (en)
Norwegian (no)
Other versions
NO932889D0 (no
NO932889L (no
Inventor
David Alker
Robert John Bass
Kelvin Cooper
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO932889D0 publication Critical patent/NO932889D0/no
Publication of NO932889L publication Critical patent/NO932889L/no
Publication of NO300592B1 publication Critical patent/NO300592B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
NO932889A 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister NO300592B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents
PCT/EP1992/000163 WO1992014734A1 (en) 1991-02-13 1992-01-24 Imidazopyridine paf/h1 antagonists

Publications (3)

Publication Number Publication Date
NO932889D0 NO932889D0 (no) 1993-08-13
NO932889L NO932889L (no) 1993-08-13
NO300592B1 true NO300592B1 (no) 1997-06-23

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932889A NO300592B1 (no) 1991-02-13 1993-08-13 Imidazopyridin PAF/H1 antagonister

Country Status (29)

Country Link
US (1) US5358953A (cg-RX-API-DMAC7.html)
EP (1) EP0572425B1 (cg-RX-API-DMAC7.html)
JP (1) JP2506541B2 (cg-RX-API-DMAC7.html)
KR (1) KR970005302B1 (cg-RX-API-DMAC7.html)
CN (1) CN1040326C (cg-RX-API-DMAC7.html)
AT (1) ATE109482T1 (cg-RX-API-DMAC7.html)
AU (1) AU650322B2 (cg-RX-API-DMAC7.html)
BR (1) BR9205615A (cg-RX-API-DMAC7.html)
CA (1) CA2099381C (cg-RX-API-DMAC7.html)
CZ (1) CZ280504B6 (cg-RX-API-DMAC7.html)
DE (1) DE69200304T2 (cg-RX-API-DMAC7.html)
DK (1) DK0572425T3 (cg-RX-API-DMAC7.html)
EG (1) EG20085A (cg-RX-API-DMAC7.html)
ES (1) ES2059212T3 (cg-RX-API-DMAC7.html)
FI (1) FI933531A7 (cg-RX-API-DMAC7.html)
GB (1) GB9102997D0 (cg-RX-API-DMAC7.html)
HU (2) HUT65947A (cg-RX-API-DMAC7.html)
IE (1) IE65125B1 (cg-RX-API-DMAC7.html)
IL (1) IL100887A (cg-RX-API-DMAC7.html)
MX (1) MX9200589A (cg-RX-API-DMAC7.html)
MY (1) MY108437A (cg-RX-API-DMAC7.html)
NO (1) NO300592B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ241597A (cg-RX-API-DMAC7.html)
PL (1) PL169304B1 (cg-RX-API-DMAC7.html)
RU (1) RU2114845C1 (cg-RX-API-DMAC7.html)
TW (1) TW227000B (cg-RX-API-DMAC7.html)
WO (1) WO1992014734A1 (cg-RX-API-DMAC7.html)
YU (1) YU48238B (cg-RX-API-DMAC7.html)
ZA (1) ZA921005B (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
AU3186395A (en) * 1994-08-10 1996-03-07 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
MX9707187A (es) * 1995-08-05 1997-11-29 British Biotech Pharm Derivados de imidazopiridina.
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
ES2381775T3 (es) 2000-08-04 2012-05-31 Dmi Biosciences, Inc. Procedimiento del uso de dicetopiperazinas y composición que las contiene
CN101947306B (zh) 2003-05-15 2014-06-18 安皮奥制药股份有限公司 T-细胞介导的疾病的治疗
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
TWI429641B (zh) 2008-01-30 2014-03-11 Nippon Zoki Pharmaceutical Co 哌啶衍生物
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ,インコーポレイテッド ジケトピペラジンを用いた医薬組成物
CN103619839B (zh) * 2011-06-28 2016-06-01 福建省闽东力捷迅药业有限公司 抗-变态反应的苯并环庚并噻吩衍生物
EP2765968A4 (en) 2011-10-10 2015-01-21 Ampio Pharmaceuticals Inc IMPLANTABLE MEDICINE PRODUCTS WITH INCREASED IMMUNO TOLERANCE AND PROCESSING AND IMPLANTATION METHODS
KR102032400B1 (ko) 2011-10-10 2019-10-15 앰피오 파마슈티컬스 인코퍼레이티드 퇴행성 관절 질환의 치료
SG10201605205VA (en) * 2011-10-28 2016-08-30 Ampio Pharmaceuticals Inc Treatment of rhinitis
KR20150132508A (ko) 2013-03-15 2015-11-25 앰피오 파마슈티컬스 인코퍼레이티드 줄기세포의 가동화, 회귀, 증식 및 분화를 위한 조성물 및 이의 사용 방법
EP4066836A1 (en) 2014-08-18 2022-10-05 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (cg-RX-API-DMAC7.html) * 1963-04-24
AU616508B2 (en) * 1988-03-15 1991-10-31 G.D. Searle & Co. Benzyl-imidazo (4,5-c) pyridines
ATE141599T1 (de) * 1988-04-28 1996-09-15 Schering Corp Kondensierte polyzyklische verbindungen, zusammenstellungen, verfahren zur herstellung und deren anwendung als paf-antagonistische, antihistaminische und/oder anti-inflammatorische agenzien
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
CA2080476A1 (en) * 1990-05-09 1991-11-10 Anthony Marfat Azabenzimidazoles in the treatment of asthma, arthritis and related diseases

Also Published As

Publication number Publication date
CA2099381C (en) 1996-07-09
IL100887A0 (en) 1992-11-15
KR970005302B1 (ko) 1997-04-15
CN1040326C (zh) 1998-10-21
TW227000B (cg-RX-API-DMAC7.html) 1994-07-21
IE920449A1 (en) 1992-08-12
NO932889D0 (no) 1993-08-13
ES2059212T3 (es) 1994-11-01
FI933531A0 (fi) 1993-08-10
RU2114845C1 (ru) 1998-07-10
EP0572425B1 (en) 1994-08-03
ZA921005B (en) 1993-08-12
US5358953A (en) 1994-10-25
NO932889L (no) 1993-08-13
AU1168392A (en) 1992-09-15
NZ241597A (en) 1993-04-28
IL100887A (en) 1996-01-19
JP2506541B2 (ja) 1996-06-12
DE69200304D1 (de) 1994-09-08
CS42592A3 (en) 1992-09-16
DK0572425T3 (da) 1994-09-12
PL169304B1 (pl) 1996-06-28
FI933531L (fi) 1993-08-10
HUT65947A (en) 1994-08-29
MY108437A (en) 1996-09-30
EG20085A (en) 1997-05-31
JPH06504992A (ja) 1994-06-09
FI933531A7 (fi) 1993-08-10
IE65125B1 (en) 1995-10-04
HU9302327D0 (en) 1993-10-28
YU48238B (sh) 1997-08-22
EP0572425A1 (en) 1993-12-08
AU650322B2 (en) 1994-06-16
HU211202A9 (en) 1995-11-28
BR9205615A (pt) 1994-05-17
WO1992014734A1 (en) 1992-09-03
DE69200304T2 (de) 1994-12-08
ATE109482T1 (de) 1994-08-15
YU14392A (sh) 1994-11-15
CA2099381A1 (en) 1992-08-14
MX9200589A (es) 1992-10-01
GB9102997D0 (en) 1991-03-27
CN1064275A (zh) 1992-09-09
CZ280504B6 (cs) 1996-02-14

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