CZ280504B6 - Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití - Google Patents

Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití Download PDF

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Publication number
CZ280504B6
CZ280504B6 CS92425A CS42592A CZ280504B6 CZ 280504 B6 CZ280504 B6 CZ 280504B6 CS 92425 A CS92425 A CS 92425A CS 42592 A CS42592 A CS 42592A CZ 280504 B6 CZ280504 B6 CZ 280504B6
Authority
CZ
Czechia
Prior art keywords
compounds
formula
pyrid
methylimidazo
piperidine
Prior art date
Application number
CS92425A
Other languages
Czech (cs)
English (en)
Inventor
David Dr. Alker
Robert John Dr. Bass
Kelvin Dr. Cooper
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CS42592A3 publication Critical patent/CS42592A3/cs
Publication of CZ280504B6 publication Critical patent/CZ280504B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
CS92425A 1991-02-13 1992-02-12 Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití CZ280504B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents

Publications (2)

Publication Number Publication Date
CS42592A3 CS42592A3 (en) 1992-09-16
CZ280504B6 true CZ280504B6 (cs) 1996-02-14

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
CS92425A CZ280504B6 (cs) 1991-02-13 1992-02-12 Imidazopyridinové deriváty jako antagonisty PAF/H1, způsob přípravy těchto sloučenin a použití

Country Status (29)

Country Link
US (1) US5358953A (cg-RX-API-DMAC7.html)
EP (1) EP0572425B1 (cg-RX-API-DMAC7.html)
JP (1) JP2506541B2 (cg-RX-API-DMAC7.html)
KR (1) KR970005302B1 (cg-RX-API-DMAC7.html)
CN (1) CN1040326C (cg-RX-API-DMAC7.html)
AT (1) ATE109482T1 (cg-RX-API-DMAC7.html)
AU (1) AU650322B2 (cg-RX-API-DMAC7.html)
BR (1) BR9205615A (cg-RX-API-DMAC7.html)
CA (1) CA2099381C (cg-RX-API-DMAC7.html)
CZ (1) CZ280504B6 (cg-RX-API-DMAC7.html)
DE (1) DE69200304T2 (cg-RX-API-DMAC7.html)
DK (1) DK0572425T3 (cg-RX-API-DMAC7.html)
EG (1) EG20085A (cg-RX-API-DMAC7.html)
ES (1) ES2059212T3 (cg-RX-API-DMAC7.html)
FI (1) FI933531A7 (cg-RX-API-DMAC7.html)
GB (1) GB9102997D0 (cg-RX-API-DMAC7.html)
HU (2) HUT65947A (cg-RX-API-DMAC7.html)
IE (1) IE65125B1 (cg-RX-API-DMAC7.html)
IL (1) IL100887A (cg-RX-API-DMAC7.html)
MX (1) MX9200589A (cg-RX-API-DMAC7.html)
MY (1) MY108437A (cg-RX-API-DMAC7.html)
NO (1) NO300592B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ241597A (cg-RX-API-DMAC7.html)
PL (1) PL169304B1 (cg-RX-API-DMAC7.html)
RU (1) RU2114845C1 (cg-RX-API-DMAC7.html)
TW (1) TW227000B (cg-RX-API-DMAC7.html)
WO (1) WO1992014734A1 (cg-RX-API-DMAC7.html)
YU (1) YU48238B (cg-RX-API-DMAC7.html)
ZA (1) ZA921005B (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
AU3186395A (en) * 1994-08-10 1996-03-07 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
MX9707187A (es) * 1995-08-05 1997-11-29 British Biotech Pharm Derivados de imidazopiridina.
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
ES2381775T3 (es) 2000-08-04 2012-05-31 Dmi Biosciences, Inc. Procedimiento del uso de dicetopiperazinas y composición que las contiene
CN101947306B (zh) 2003-05-15 2014-06-18 安皮奥制药股份有限公司 T-细胞介导的疾病的治疗
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
TWI429641B (zh) 2008-01-30 2014-03-11 Nippon Zoki Pharmaceutical Co 哌啶衍生物
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
CN103619839B (zh) * 2011-06-28 2016-06-01 福建省闽东力捷迅药业有限公司 抗-变态反应的苯并环庚并噻吩衍生物
EP2765968A4 (en) 2011-10-10 2015-01-21 Ampio Pharmaceuticals Inc IMPLANTABLE MEDICINE PRODUCTS WITH INCREASED IMMUNO TOLERANCE AND PROCESSING AND IMPLANTATION METHODS
KR102032400B1 (ko) 2011-10-10 2019-10-15 앰피오 파마슈티컬스 인코퍼레이티드 퇴행성 관절 질환의 치료
SG10201605205VA (en) * 2011-10-28 2016-08-30 Ampio Pharmaceuticals Inc Treatment of rhinitis
KR20150132508A (ko) 2013-03-15 2015-11-25 앰피오 파마슈티컬스 인코퍼레이티드 줄기세포의 가동화, 회귀, 증식 및 분화를 위한 조성물 및 이의 사용 방법
EP4066836A1 (en) 2014-08-18 2022-10-05 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (cg-RX-API-DMAC7.html) * 1963-04-24
AU616508B2 (en) * 1988-03-15 1991-10-31 G.D. Searle & Co. Benzyl-imidazo (4,5-c) pyridines
ATE141599T1 (de) * 1988-04-28 1996-09-15 Schering Corp Kondensierte polyzyklische verbindungen, zusammenstellungen, verfahren zur herstellung und deren anwendung als paf-antagonistische, antihistaminische und/oder anti-inflammatorische agenzien
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
CA2080476A1 (en) * 1990-05-09 1991-11-10 Anthony Marfat Azabenzimidazoles in the treatment of asthma, arthritis and related diseases

Also Published As

Publication number Publication date
CA2099381C (en) 1996-07-09
IL100887A0 (en) 1992-11-15
KR970005302B1 (ko) 1997-04-15
CN1040326C (zh) 1998-10-21
TW227000B (cg-RX-API-DMAC7.html) 1994-07-21
IE920449A1 (en) 1992-08-12
NO932889D0 (no) 1993-08-13
ES2059212T3 (es) 1994-11-01
FI933531A0 (fi) 1993-08-10
RU2114845C1 (ru) 1998-07-10
EP0572425B1 (en) 1994-08-03
ZA921005B (en) 1993-08-12
NO300592B1 (no) 1997-06-23
US5358953A (en) 1994-10-25
NO932889L (no) 1993-08-13
AU1168392A (en) 1992-09-15
NZ241597A (en) 1993-04-28
IL100887A (en) 1996-01-19
JP2506541B2 (ja) 1996-06-12
DE69200304D1 (de) 1994-09-08
CS42592A3 (en) 1992-09-16
DK0572425T3 (da) 1994-09-12
PL169304B1 (pl) 1996-06-28
FI933531L (fi) 1993-08-10
HUT65947A (en) 1994-08-29
MY108437A (en) 1996-09-30
EG20085A (en) 1997-05-31
JPH06504992A (ja) 1994-06-09
FI933531A7 (fi) 1993-08-10
IE65125B1 (en) 1995-10-04
HU9302327D0 (en) 1993-10-28
YU48238B (sh) 1997-08-22
EP0572425A1 (en) 1993-12-08
AU650322B2 (en) 1994-06-16
HU211202A9 (en) 1995-11-28
BR9205615A (pt) 1994-05-17
WO1992014734A1 (en) 1992-09-03
DE69200304T2 (de) 1994-12-08
ATE109482T1 (de) 1994-08-15
YU14392A (sh) 1994-11-15
CA2099381A1 (en) 1992-08-14
MX9200589A (es) 1992-10-01
GB9102997D0 (en) 1991-03-27
CN1064275A (zh) 1992-09-09

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20000212