NO2994485T3 - - Google Patents
Info
- Publication number
- NO2994485T3 NO2994485T3 NO14722194A NO14722194A NO2994485T3 NO 2994485 T3 NO2994485 T3 NO 2994485T3 NO 14722194 A NO14722194 A NO 14722194A NO 14722194 A NO14722194 A NO 14722194A NO 2994485 T3 NO2994485 T3 NO 2994485T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/12—Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Water Supply & Treatment (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13305593 | 2013-05-06 | ||
PCT/EP2014/059246 WO2014180852A1 (fr) | 2013-05-06 | 2014-05-06 | Procédé continu à étapes multiples pour la purification d'anticorps |
EP14722194.9A EP2994485B1 (fr) | 2013-05-06 | 2014-05-06 | Procede continu en plusieurs etapes destine a la purification des anticorps |
Publications (1)
Publication Number | Publication Date |
---|---|
NO2994485T3 true NO2994485T3 (fr) | 2018-06-09 |
Family
ID=48430636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO14722194A NO2994485T3 (fr) | 2013-05-06 | 2014-05-06 |
Country Status (19)
Country | Link |
---|---|
US (1) | US10793622B2 (fr) |
EP (2) | EP3301115B1 (fr) |
JP (2) | JP6463734B2 (fr) |
KR (1) | KR102272851B1 (fr) |
CN (2) | CN116003579A (fr) |
AU (1) | AU2014264697B2 (fr) |
BR (1) | BR112015027812B1 (fr) |
CA (1) | CA2911462C (fr) |
CY (1) | CY1125281T1 (fr) |
DK (2) | DK3301115T3 (fr) |
ES (2) | ES2665645T3 (fr) |
HU (2) | HUE057119T2 (fr) |
IL (1) | IL242408B (fr) |
MX (1) | MX368177B (fr) |
NO (1) | NO2994485T3 (fr) |
RU (1) | RU2662668C2 (fr) |
SG (1) | SG11201508968XA (fr) |
TW (2) | TWI631132B (fr) |
WO (1) | WO2014180852A1 (fr) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
CN111172135A (zh) * | 2012-10-24 | 2020-05-19 | 建新公司 | 使用mes和mops作为流动相改性剂从多峰树脂洗脱生物分子 |
CN105555795A (zh) * | 2013-09-17 | 2016-05-04 | 株式会社钟化 | 新抗体纯化方法和由该方法得到的抗体、以及使用了阳离子交换基团的新抗体纯化法和由该方法得到的抗体 |
WO2015105955A1 (fr) | 2014-01-08 | 2015-07-16 | Flodesign Sonics, Inc. | Dispositif d'acoustophorèse avec double chambre acoustophorétique |
GB201503578D0 (en) * | 2015-03-03 | 2015-04-15 | Ge Healthcare Bio Sciences Ab | Sanitization method for affinity chromatography matrices |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
EP3015542A1 (fr) * | 2015-05-07 | 2016-05-04 | Bayer Technology Services GmbH | Installation modulaire et procédé de production continue, présentant une réduction de germe et/ou préparation d'un produit |
US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
US20170101437A1 (en) * | 2015-10-09 | 2017-04-13 | Hetero Drugs Ltd. | Process for purification of darbepoetin alfa |
US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
US20190211055A1 (en) * | 2016-09-14 | 2019-07-11 | Kinbio Ltd. | Methods of purifying and qualifying antibodies |
EP3529347A1 (fr) | 2016-10-19 | 2019-08-28 | Flodesign Sonics, Inc. | Extraction par affinité de cellules par un procédé acoustique |
CA3057286A1 (fr) * | 2017-03-24 | 2018-09-27 | Council Of Scientific And Industrial Research | Procede de purification de fragments d'anticorps recombinants |
GB201711481D0 (en) * | 2017-07-17 | 2017-08-30 | Ucb Biopharma Sprl | Protein purification |
EP3676375A4 (fr) | 2017-08-31 | 2021-04-07 | Green Cross Corporation | Procédé de purification d'une protéine de sulfatase |
KR102439221B1 (ko) | 2017-12-14 | 2022-09-01 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
EP3769083A1 (fr) | 2018-03-21 | 2021-01-27 | Waters Technologies Corporation | Préparation d'échantillon à base d'affinité élevée sans anticorps, sorbants, dispositifs et méthodes |
EP3546475A1 (fr) * | 2018-03-27 | 2019-10-02 | Sanofi | Processus d'écoulement intégral pour purifier des protéines recombinées |
US20190367858A1 (en) * | 2018-06-01 | 2019-12-05 | Lonza Ltd. | Midscale Model For Organic Growth and Phasing |
KR102337683B1 (ko) * | 2018-09-21 | 2021-12-13 | 주식회사 녹십자 | 고효율 항-tfpi 항체 조성물 |
EP3636657A1 (fr) * | 2018-10-08 | 2020-04-15 | Ablynx N.V. | Procédé de purification d'anticorps sans chromatographie |
WO2020084503A1 (fr) * | 2018-10-26 | 2020-04-30 | Cadila Healthcare Limited | Composition comprenant un anticorps ayant un niveau réduit de variants basiques de celui-ci |
WO2020183332A1 (fr) * | 2019-03-11 | 2020-09-17 | Intas Pharmaceuticals Ltd. | Purification d'adalimumab à l'aide d'une chromatographie en tandem |
EP3947705A1 (fr) * | 2019-04-03 | 2022-02-09 | Genzyme Corporation | Production en continu de protéines recombinées |
WO2020258704A1 (fr) * | 2019-06-28 | 2020-12-30 | 信达生物制药(苏州)有限公司 | Procédé chromatographique à écoulement continu sans interruption |
KR102154952B1 (ko) * | 2020-02-21 | 2020-09-10 | 프레스티지바이오로직스 주식회사 | 아달리무맙의 Non-Protein A 정제방법 |
CN112574321B (zh) * | 2020-12-30 | 2023-10-20 | 上海赛金生物医药有限公司 | 一种捕获单克隆抗体-肿瘤坏死因子融合蛋白的亲和纯化方法 |
WO2022234412A1 (fr) | 2021-05-03 | 2022-11-10 | Lupin Limited | Procédé de purification de protéines de fusion fc |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2070855T5 (es) | 1987-10-23 | 2004-03-01 | Schering Corporation | Metodo para purificar una proteina. |
ES2126775T3 (es) | 1993-09-21 | 1999-04-01 | Hemosol Inc | Procedimiento cromatografico de desplazamiento y producto de hemoglobina purificada. |
CA2106612C (fr) | 1993-09-21 | 2001-02-06 | Diana Pliura | Processus de chromatographie a deplacement |
US5891741A (en) | 1997-05-16 | 1999-04-06 | Coulter International Corp. | Antibody-aminodextran-phycobiliprotein conjugates |
CN1136317C (zh) | 1999-03-12 | 2004-01-28 | 中国人民解放军第四军医大学 | 单克隆抗体双段和单段的制备方法 |
US20020009445A1 (en) | 2000-07-12 | 2002-01-24 | Yansheng Du | Human beta-amyloid antibody and use thereof for treatment of alzheimer's disease |
US6602855B2 (en) | 2001-04-30 | 2003-08-05 | Syn X Pharma, Inc. | Biopolymer marker indicative of disease state having a molecular weight of 1449 daltons |
CN1504482A (zh) | 2002-12-03 | 2004-06-16 | 北京优力凯生物技术有限责任公司 | 无细胞百日咳抗原蛋白的分离纯化方法 |
EP2468769A1 (fr) | 2004-04-21 | 2012-06-27 | The Brigham and Women's Hospital, Inc. | Peptides à liaison de glucosamine poly-N-acétyle (PNAG/DPNAG) et procédés d'utilisation |
US7714112B2 (en) * | 2004-10-21 | 2010-05-11 | Ge Healthcare Bio-Sciences Ab | Method of antibody purification |
IL296666A (en) | 2005-03-23 | 2022-11-01 | Genmab As | Antibodies against 38cd for the treatment of multiple myeloma |
CN1814775A (zh) | 2005-12-06 | 2006-08-09 | 中国海洋大学 | 一种抗病毒活性寡聚肽的制备方法 |
EP1914242A1 (fr) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Nouveau anticorps Anti-CD38 pour le traitement du cancer |
DE602008005885D1 (de) | 2007-07-11 | 2011-05-12 | Novo Nordisk As | Aufreinigung von faktor viii unter verwendung eine |
ES2639016T3 (es) | 2007-11-16 | 2017-10-25 | The Rockefeller University | Anticuerpos específicos para la forma protofibrilar de proteína beta-amiloide |
TWI472339B (zh) * | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
EP2615112A3 (fr) * | 2008-02-29 | 2013-08-21 | Biogen Idec MA Inc. | Protéines de fusion d'immunoglobuline purifiées et leurs procédés de purification |
WO2009138484A2 (fr) | 2008-05-15 | 2009-11-19 | Novo Nordisk A/S | Procédé de purification d'anticorps |
BRPI0915948A2 (pt) * | 2008-07-18 | 2019-04-09 | Talecris Biotherapeutics Inc | método de preparar inibidor de alfa-1 proteinase |
JPWO2010071208A1 (ja) | 2008-12-19 | 2012-05-31 | 武田薬品工業株式会社 | 抗体の精製方法 |
US20120022239A1 (en) | 2009-01-13 | 2012-01-26 | Ge Healthcare Bio-Sciences Ab | Precipitation of biomolecules with negatively charged polymers |
KR101224468B1 (ko) * | 2009-05-20 | 2013-01-23 | 주식회사 파멥신 | 신규한 형태의 이중표적항체 및 그 용도 |
CN107188960A (zh) * | 2009-08-07 | 2017-09-22 | Emd密理博公司 | 从样品的一或多种杂质中纯化靶蛋白的方法 |
US9527010B2 (en) * | 2009-09-25 | 2016-12-27 | Ge Healthcare Bio-Sciences Corp. | Separation system and method |
US20120208986A1 (en) * | 2009-10-20 | 2012-08-16 | Wenger Marc D | Use of mixed mode chromatography for the capture and purification of basic antibody products |
US20130178608A1 (en) | 2009-12-29 | 2013-07-11 | Samir Kulkarni | Protein purification by ion exchange |
ES2534936T3 (es) | 2010-08-02 | 2015-04-30 | Ratiopharm Gmbh | Método para producir y purificar una sialiltransferasa soluble activa |
WO2012125735A1 (fr) * | 2011-03-15 | 2012-09-20 | Abott Laboratories | Approche intégrée à isolement et purification d'anticorps |
KR102058254B1 (ko) * | 2011-03-29 | 2019-12-20 | 글락소스미스클라인 엘엘씨 | 단백질 정제용 완충제 시스템 |
US8445284B2 (en) | 2011-06-17 | 2013-05-21 | Constitution Medical, Inc. | Fixative and staining solutions |
WO2013028330A2 (fr) | 2011-08-19 | 2013-02-28 | Emd Millipore Corporation | Procédés pour réduire le niveau d'une ou de plusieurs impuretés dans un échantillon pendant un procédé de purification de protéines |
EP2578286A1 (fr) * | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Procédé et appareil de purification chromatographique |
PE20141413A1 (es) * | 2011-10-25 | 2014-10-25 | Onclave Therapeutics Ltd | Formulaciones de anticuerpo y metodos |
WO2013075740A1 (fr) | 2011-11-23 | 2013-05-30 | Sanofi | Procédé de purification d'anticorps |
-
2014
- 2014-05-06 HU HUE17200909A patent/HUE057119T2/hu unknown
- 2014-05-06 SG SG11201508968XA patent/SG11201508968XA/en unknown
- 2014-05-06 MX MX2015015482A patent/MX368177B/es active IP Right Grant
- 2014-05-06 CN CN202310118200.6A patent/CN116003579A/zh active Pending
- 2014-05-06 TW TW103116153A patent/TWI631132B/zh not_active IP Right Cessation
- 2014-05-06 AU AU2014264697A patent/AU2014264697B2/en active Active
- 2014-05-06 RU RU2015151869A patent/RU2662668C2/ru active
- 2014-05-06 DK DK17200909.4T patent/DK3301115T3/da active
- 2014-05-06 TW TW107117528A patent/TWI675041B/zh not_active IP Right Cessation
- 2014-05-06 US US14/889,397 patent/US10793622B2/en active Active
- 2014-05-06 ES ES14722194.9T patent/ES2665645T3/es active Active
- 2014-05-06 HU HUE14722194A patent/HUE038741T2/hu unknown
- 2014-05-06 ES ES17200909T patent/ES2905675T3/es active Active
- 2014-05-06 KR KR1020157032904A patent/KR102272851B1/ko active IP Right Grant
- 2014-05-06 CN CN201480038360.9A patent/CN105358572A/zh active Pending
- 2014-05-06 WO PCT/EP2014/059246 patent/WO2014180852A1/fr active Application Filing
- 2014-05-06 EP EP17200909.4A patent/EP3301115B1/fr active Active
- 2014-05-06 BR BR112015027812-4A patent/BR112015027812B1/pt active IP Right Grant
- 2014-05-06 DK DK14722194.9T patent/DK2994485T3/en active
- 2014-05-06 CA CA2911462A patent/CA2911462C/fr active Active
- 2014-05-06 JP JP2016512344A patent/JP6463734B2/ja active Active
- 2014-05-06 NO NO14722194A patent/NO2994485T3/no unknown
- 2014-05-06 EP EP14722194.9A patent/EP2994485B1/fr active Active
-
2015
- 2015-11-02 IL IL242408A patent/IL242408B/en active IP Right Grant
-
2019
- 2019-01-10 JP JP2019002288A patent/JP2019104735A/ja active Pending
-
2022
- 2022-02-09 CY CY20221100113T patent/CY1125281T1/el unknown