MX2015015482A - Proceso continuo de multiples etapas para purificar anticuerpos. - Google Patents

Proceso continuo de multiples etapas para purificar anticuerpos.

Info

Publication number
MX2015015482A
MX2015015482A MX2015015482A MX2015015482A MX2015015482A MX 2015015482 A MX2015015482 A MX 2015015482A MX 2015015482 A MX2015015482 A MX 2015015482A MX 2015015482 A MX2015015482 A MX 2015015482A MX 2015015482 A MX2015015482 A MX 2015015482A
Authority
MX
Mexico
Prior art keywords
multistep process
purifying antibodies
continuous multistep
continuous
antibodies
Prior art date
Application number
MX2015015482A
Other languages
English (en)
Other versions
MX368177B (es
Inventor
Didier Duthe
Laure Landric-Burtin
Céline Hemet
Benoît Mothes
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2015015482A publication Critical patent/MX2015015482A/es
Publication of MX368177B publication Critical patent/MX368177B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12—Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Water Supply & Treatment (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

La invención se refiere a un proceso cromatográfico de tres etapas para la purificación de proteínas a pequeña y gran escala, específicamente anticuerpos monoclonales utilizando solo cuatro soluciones amortiguadoras hechas de una solución madre.
MX2015015482A 2013-05-06 2014-05-06 Proceso continuo de múltiples etapas para purificar anticuerpos. MX368177B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13305593 2013-05-06
PCT/EP2014/059246 WO2014180852A1 (en) 2013-05-06 2014-05-06 Continuous multistep process for purifying antibodies

Publications (2)

Publication Number Publication Date
MX2015015482A true MX2015015482A (es) 2016-03-21
MX368177B MX368177B (es) 2019-09-23

Family

ID=48430636

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015015482A MX368177B (es) 2013-05-06 2014-05-06 Proceso continuo de múltiples etapas para purificar anticuerpos.

Country Status (19)

Country Link
US (1) US10793622B2 (es)
EP (2) EP2994485B1 (es)
JP (2) JP6463734B2 (es)
KR (1) KR102272851B1 (es)
CN (2) CN105358572A (es)
AU (1) AU2014264697B2 (es)
BR (1) BR112015027812B1 (es)
CA (1) CA2911462C (es)
CY (1) CY1125281T1 (es)
DK (2) DK3301115T3 (es)
ES (2) ES2665645T3 (es)
HU (2) HUE038741T2 (es)
IL (1) IL242408B (es)
MX (1) MX368177B (es)
NO (1) NO2994485T3 (es)
RU (1) RU2662668C2 (es)
SG (1) SG11201508968XA (es)
TW (2) TWI675041B (es)
WO (1) WO2014180852A1 (es)

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Also Published As

Publication number Publication date
JP2019104735A (ja) 2019-06-27
KR102272851B1 (ko) 2021-07-02
RU2015151869A (ru) 2017-06-13
KR20160005047A (ko) 2016-01-13
IL242408B (en) 2020-04-30
AU2014264697A1 (en) 2015-11-26
CY1125281T1 (el) 2023-06-09
CN105358572A (zh) 2016-02-24
CN116003579A (zh) 2023-04-25
WO2014180852A1 (en) 2014-11-13
ES2665645T3 (es) 2018-04-26
US20160083454A1 (en) 2016-03-24
TWI631132B (zh) 2018-08-01
TWI675041B (zh) 2019-10-21
BR112015027812A2 (pt) 2017-07-25
ES2905675T3 (es) 2022-04-11
EP3301115A1 (en) 2018-04-04
JP6463734B2 (ja) 2019-02-06
AU2014264697B2 (en) 2019-08-22
BR112015027812B1 (pt) 2021-03-30
HUE038741T2 (hu) 2018-11-28
MX368177B (es) 2019-09-23
DK3301115T3 (da) 2022-01-31
NO2994485T3 (es) 2018-06-09
EP2994485B1 (en) 2018-01-10
EP3301115B1 (en) 2021-11-10
HUE057119T2 (hu) 2022-04-28
TW201908331A (zh) 2019-03-01
TW201522363A (zh) 2015-06-16
CA2911462C (en) 2021-04-06
US10793622B2 (en) 2020-10-06
JP2016519137A (ja) 2016-06-30
EP2994485A1 (en) 2016-03-16
DK2994485T3 (en) 2018-04-23
SG11201508968XA (en) 2015-11-27
CA2911462A1 (en) 2014-11-13
RU2662668C2 (ru) 2018-07-26

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