NO20091491L - Fluorerte catharantinderivater, deres fremstilling og deres anvendelse som vincadimore alkaloidforlopere - Google Patents

Fluorerte catharantinderivater, deres fremstilling og deres anvendelse som vincadimore alkaloidforlopere

Info

Publication number
NO20091491L
NO20091491L NO20091491A NO20091491A NO20091491L NO 20091491 L NO20091491 L NO 20091491L NO 20091491 A NO20091491 A NO 20091491A NO 20091491 A NO20091491 A NO 20091491A NO 20091491 L NO20091491 L NO 20091491L
Authority
NO
Norway
Prior art keywords
fluorinated
derivatives
vincadimore
catharantine
preparation
Prior art date
Application number
NO20091491A
Other languages
English (en)
Norwegian (no)
Inventor
Lionel Moisan
Sebastien Comesse
Emerson Giovanelli
Bernard Rousseau
Eric Doris
Paul Hellier
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Publication of NO20091491L publication Critical patent/NO20091491L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
NO20091491A 2006-09-20 2009-04-16 Fluorerte catharantinderivater, deres fremstilling og deres anvendelse som vincadimore alkaloidforlopere NO20091491L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82624506P 2006-09-20 2006-09-20
FR0608226A FR2905949B1 (fr) 2006-09-20 2006-09-20 Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca
PCT/EP2007/059991 WO2008034882A1 (en) 2006-09-20 2007-09-20 Fluorinated catharanthine derivatives, their preparation and their utilisation as vinca dimeric alkaloid precursors

Publications (1)

Publication Number Publication Date
NO20091491L true NO20091491L (no) 2009-05-13

Family

ID=37982436

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091491A NO20091491L (no) 2006-09-20 2009-04-16 Fluorerte catharantinderivater, deres fremstilling og deres anvendelse som vincadimore alkaloidforlopere

Country Status (22)

Country Link
US (1) US8101748B2 (zh)
EP (1) EP2078017B9 (zh)
JP (1) JP5280364B2 (zh)
KR (1) KR20090063256A (zh)
CN (1) CN101522679B (zh)
AT (1) ATE478871T1 (zh)
AU (1) AU2007298920B2 (zh)
BR (1) BRPI0717063A2 (zh)
CA (1) CA2664040A1 (zh)
DE (1) DE602007008748D1 (zh)
ES (1) ES2349387T3 (zh)
FR (1) FR2905949B1 (zh)
IL (1) IL197640A (zh)
MA (1) MA31134B1 (zh)
MX (1) MX2009003121A (zh)
NO (1) NO20091491L (zh)
NZ (1) NZ575884A (zh)
PL (1) PL2078017T3 (zh)
PT (1) PT2078017E (zh)
RU (1) RU2448957C2 (zh)
TN (1) TN2009000097A1 (zh)
WO (1) WO2008034882A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011103007A2 (en) * 2010-02-22 2011-08-25 The Scripps Research Institute 10'-fluorinated vinca alkaloids provide enhanced biological activity against mdr cancer cells
EP2987794B1 (en) * 2013-04-19 2018-05-30 Jinan University Vinblastine derivatives, preparation method therefor and application thereof
CN105503907B (zh) * 2016-01-18 2018-01-09 北京大学 对映选择性合成Vinca类生物碱的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180924B (en) * 1977-05-20 1983-05-30 Richter Gedeon Vegyeszet Process for producing leurosine-type alkaloides
FR2632643B1 (fr) * 1988-06-10 1990-09-07 Adir Nouveau procede de preparation de derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique
JPH0341081A (ja) * 1989-07-10 1991-02-21 Mitsui Petrochem Ind Ltd 二量体アルカロイド類の製造方法
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation
CN1218950C (zh) * 2004-02-18 2005-09-14 东北林业大学 一种长春碱的生产方法

Also Published As

Publication number Publication date
AU2007298920B2 (en) 2012-03-08
ATE478871T1 (de) 2010-09-15
US8101748B2 (en) 2012-01-24
IL197640A0 (en) 2009-12-24
BRPI0717063A2 (pt) 2013-10-15
TN2009000097A1 (en) 2010-08-19
FR2905949B1 (fr) 2008-11-21
MX2009003121A (es) 2009-07-31
EP2078017A1 (en) 2009-07-15
CN101522679B (zh) 2013-12-18
JP5280364B2 (ja) 2013-09-04
WO2008034882A1 (en) 2008-03-27
FR2905949A1 (fr) 2008-03-21
CN101522679A (zh) 2009-09-02
DE602007008748D1 (de) 2010-10-07
KR20090063256A (ko) 2009-06-17
CA2664040A1 (en) 2008-03-27
NZ575884A (en) 2011-09-30
RU2448957C2 (ru) 2012-04-27
JP2010504303A (ja) 2010-02-12
EP2078017B1 (en) 2010-08-25
PL2078017T3 (pl) 2011-02-28
IL197640A (en) 2013-03-24
US20100093997A1 (en) 2010-04-15
ES2349387T3 (es) 2010-12-30
RU2009113535A (ru) 2010-10-27
MA31134B1 (fr) 2010-02-01
AU2007298920A1 (en) 2008-03-27
PT2078017E (pt) 2010-11-09
EP2078017B9 (en) 2011-09-07

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