NO20090332L - 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler - Google Patents

4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler

Info

Publication number
NO20090332L
NO20090332L NO20090332A NO20090332A NO20090332L NO 20090332 L NO20090332 L NO 20090332L NO 20090332 A NO20090332 A NO 20090332A NO 20090332 A NO20090332 A NO 20090332A NO 20090332 L NO20090332 L NO 20090332L
Authority
NO
Norway
Prior art keywords
arylamino
amino
preparation
antiviral agents
pyrimidine derivatives
Prior art date
Application number
NO20090332A
Other languages
English (en)
Inventor
Michaela Schmidtke
Vadim Makarov
Peter Wutzler
Hans-Martin Dahse
Original Assignee
Dritte Patentportfolio Beteili
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dritte Patentportfolio Beteili filed Critical Dritte Patentportfolio Beteili
Publication of NO20090332L publication Critical patent/NO20090332L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Abstract

Foreliggende oppfinnelse gjelder 4-amino-3-arylamino-6-arylpyrazolo-[3,4-d]pyrimidinderivater, en fremgangsmåte for fremstilling av disse og anvendelse av dem som antivirale midler. Formålet var å tilveiebringe nye forbindelser som kan benyttes som midler for f.eks. behandling av picornavirusinfeksjoner og som unngår problemer forbundet med kjente medikamenter, nærmere bestemt vedrørende resistens og intoleranse. Dette formålet oppnås ved hjelp av forbindelser med den generelle formel I.
NO20090332A 2006-06-22 2009-01-21 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler NO20090332L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006029074A DE102006029074A1 (de) 2006-06-22 2006-06-22 4-Amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung als antivirale Wirkstoffe
PCT/DE2007/001104 WO2007147401A1 (de) 2006-06-22 2007-06-20 4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-derivate, verfahren zu ihrer herstellung und deren verwendung als antivirale wirkstoffe

Publications (1)

Publication Number Publication Date
NO20090332L true NO20090332L (no) 2009-03-12

Family

ID=38606873

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090332A NO20090332L (no) 2006-06-22 2009-01-21 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler

Country Status (18)

Country Link
US (1) US8962634B2 (no)
EP (1) EP2049540B1 (no)
JP (1) JP5171815B2 (no)
KR (1) KR101107839B1 (no)
CN (1) CN101553489B (no)
AT (1) ATE492548T1 (no)
AU (1) AU2007262524B2 (no)
BR (1) BRPI0713488B1 (no)
CA (1) CA2655754C (no)
DE (2) DE102006029074A1 (no)
ES (1) ES2359677T3 (no)
IL (1) IL195837A0 (no)
NO (1) NO20090332L (no)
NZ (1) NZ573849A (no)
RU (1) RU2456288C2 (no)
SG (1) SG173316A1 (no)
WO (1) WO2007147401A1 (no)
ZA (1) ZA200900165B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2751109T1 (sl) * 2011-09-02 2017-03-31 Incyte Holdings Corporation Heterociklilamini kot inhibitorji pi3k
DE102011116373A1 (de) 2011-10-14 2013-04-18 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Methode zur Herstellung von 4-Amino-3-arylamino-6-arylpyrazolo[3, 4-d]pyrimidinen
JP6071012B2 (ja) 2011-10-14 2017-02-01 ドリッテ パテントポルトフォーリオ ベタイリグングスゲゼルシャフト エムベーハー ウント コー．カーゲー ４−アミノ−３−フェニルアミノ−６−フェニルピラゾロ［３，４−ｄ］ピリミジン誘導体、その製造および抗ウイルス剤としての使用
DE102012004736A1 (de) 2011-10-20 2013-04-25 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-Derivate und deren Verwendung als antivirale Wirkstoffe
WO2016044656A1 (en) 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
ES2662822T3 (es) 2015-03-04 2018-04-09 Scandion Oncology A/S Derivados de 4-amino-3-fenilamino-6-fenilpirazol[3,4-d]pirimidina para uso como inhibidores de la BCRP en tratamientos terapéuticos

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965643A (en) 1960-12-20 Derivatives of pyrazolo
US3551428A (en) 1956-02-10 1970-12-29 Ciba Geigy Corp New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE1088503B (de) * 1957-12-06 1960-09-08 Ciba Geigy Verfahren zur Herstellung von 3-Amino-pyrazolo-[3,4-d]-pyrimidinen
DE3712735A1 (de) 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
CA2100863A1 (en) 1991-01-23 1992-07-24 David A. Bullough Adenosine kinase inhibitors
US5294612A (en) * 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
TW370529B (en) 1992-12-17 1999-09-21 Pfizer Pyrazolopyrimidines
US5646152A (en) 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
CZ27399A3 (cs) * 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
MXPA06009462A (es) * 2004-02-27 2007-03-15 Hoffmann La Roche Derivados pirazolo heteroaril fusionados.
TW200626157A (en) * 2004-09-30 2006-08-01 Tibotec Pharm Ltd HCV inhibiting bi-cyclic pyrimidines

Also Published As

Publication number Publication date
EP2049540A1 (de) 2009-04-22
CN101553489A (zh) 2009-10-07
AU2007262524A1 (en) 2007-12-27
ATE492548T1 (de) 2011-01-15
WO2007147401A1 (de) 2007-12-27
CA2655754A1 (en) 2007-12-27
IL195837A0 (en) 2009-09-01
ES2359677T3 (es) 2011-05-25
JP5171815B2 (ja) 2013-03-27
AU2007262524B2 (en) 2011-12-01
RU2456288C2 (ru) 2012-07-20
ZA200900165B (en) 2009-12-30
NZ573849A (en) 2011-11-25
BRPI0713488A2 (pt) 2012-10-23
JP2009541230A (ja) 2009-11-26
CN101553489B (zh) 2013-07-17
DE502007006042D1 (de) 2011-02-03
BRPI0713488B1 (pt) 2022-04-12
CA2655754C (en) 2012-02-07
KR101107839B1 (ko) 2012-02-09
DE102006029074A1 (de) 2007-12-27
SG173316A1 (en) 2011-08-29
US8962634B2 (en) 2015-02-24
KR20090071536A (ko) 2009-07-01
US20100010018A1 (en) 2010-01-14
RU2009101920A (ru) 2010-07-27
EP2049540B1 (de) 2010-12-22

Similar Documents

Publication Publication Date Title
NO20063231L (no) Pyrido[2,3-D]pyrimidin-2,4-diaminer som PDE 2 inhibitorer
NO20071593L (no) Pyrimidinderivater
CY1114925T1 (el) Χορηγηση αναστολεων διπεπτιδυλοπεπτιδασης
SG151254A1 (en) Substituted morpholine and thiomorpholine derivatives
WO2005110410A3 (en) Kinase inhibitors as therapeutic agents
SE0202463D0 (sv) Novel compounds
ATE460158T1 (de) Purin-derivate als a2a-rezeptor-agonisten
GEP20156282B (en) Compounds and compositions as protein kinase inhibitors
EA200970669A1 (ru) Производные 2-амино-5,7-дигидро-6н-пирроло[3,4-d]пиримидина в качестве ингибиторов hsp-90, предназначенные для лечения рака
NO20066055L (no) Pyridinderivater
NO20085099L (no) Puritonderivativer som HM74A agonister
ATE553106T1 (de) Heteroarylpyrrolopyridinone als kinaseinhibitoren
MX2009011579A (es) Pirimidinonas como moduladores de caseina cinasa ii (ck2).
NO20083708L (no) 4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
WO2007146124A3 (en) Deuterated tadalafil derivatives
DK1611144T3 (da) Derivater af 2-(8,9-dioxo-2,6-diazabicyclo(5.2.0)non-1(7)-en-2-yl)alkyl-phosphonsyre og deres avendelse som n-methyl-D-aspartat (NMDA)-receptor-antagonister
NO20090332L (no) 4-amino-3-arylamino-6-arylpyrazol[3,4-D]pyrimidinderivater, fremgangsmater for deres fremstilling og dere anvendelse som antivirale midler
ECSP099442A (es) Derivados de heteroaril-pirrolidinil- y -piperidinil-cetona
NO20080033L (no) Kinolinderivater som NK3-antagonister
RS53211B (en) PYRIDO [2,3-d] PYRIMIDINE DERIVATIVES, THEIR PRODUCTION, THEIR USE IN THERAPY
ATE496918T1 (de) Als a2b-adenosinrezeptorantagonisten geeignete 5- phenyl-6-pyridin-4-yl-1,3-dihydro-2h-imidazoä4, - büpyridin-2-onderivate
NO20080110L (no) Benzimidazolderivativer som 5-HT6,5-HT24
TW200628153A (en) Novel compounds
ECSP088621A (es) Derivados de triazoloanilinopirimidina para uso como agentes antivirales
SE0202461D0 (sv) Novel compounds

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application