NO20091051L - Renseprosess for montelukast og dets aminsalter - Google Patents
Renseprosess for montelukast og dets aminsalterInfo
- Publication number
- NO20091051L NO20091051L NO20091051A NO20091051A NO20091051L NO 20091051 L NO20091051 L NO 20091051L NO 20091051 A NO20091051 A NO 20091051A NO 20091051 A NO20091051 A NO 20091051A NO 20091051 L NO20091051 L NO 20091051L
- Authority
- NO
- Norway
- Prior art keywords
- montelukast
- salts
- purification process
- amine salts
- treo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06118690A EP1886998A1 (en) | 2006-08-09 | 2006-08-09 | Purification process of montelukast and its amine salts |
PCT/EP2007/058180 WO2008017669A1 (en) | 2006-08-09 | 2007-08-07 | Purification process of montelukast and its amine salts |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20091051L true NO20091051L (no) | 2009-05-05 |
Family
ID=37625598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091051A NO20091051L (no) | 2006-08-09 | 2009-03-09 | Renseprosess for montelukast og dets aminsalter |
Country Status (19)
Country | Link |
---|---|
US (1) | US8188285B2 (pt) |
EP (2) | EP1886998A1 (pt) |
JP (1) | JP5188501B2 (pt) |
KR (1) | KR20090035696A (pt) |
CN (1) | CN101501000B (pt) |
AT (1) | ATE515498T1 (pt) |
AU (1) | AU2007283615A1 (pt) |
CA (1) | CA2657775A1 (pt) |
ES (1) | ES2372414T3 (pt) |
HR (1) | HRP20110575T1 (pt) |
IL (1) | IL196303A (pt) |
MX (1) | MX2009000524A (pt) |
NO (1) | NO20091051L (pt) |
PL (1) | PL2077996T3 (pt) |
PT (1) | PT2077996E (pt) |
RU (1) | RU2009108272A (pt) |
SI (1) | SI2077996T1 (pt) |
WO (1) | WO2008017669A1 (pt) |
ZA (1) | ZA200900890B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE497492T1 (de) | 2005-07-05 | 2011-02-15 | Teva Pharma | Reinigung von montelukast |
KR101469015B1 (ko) * | 2008-02-25 | 2014-12-05 | 주식회사 종근당 | 몬테루카스트의 제조방법 및 이에 사용되는 중간체 |
US20110040095A1 (en) * | 2008-03-17 | 2011-02-17 | Dr. Reddy's Laboratories Ltd. | Preparation of montelukast and its salts |
KR101123292B1 (ko) | 2008-09-26 | 2012-03-19 | 주식회사 엘지생명과학 | 몬테루카스트 나트륨염의 제조방법 |
EP2552892A1 (en) | 2010-03-31 | 2013-02-06 | KRKA, D.D., Novo Mesto | Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein |
KR100990046B1 (ko) * | 2010-07-30 | 2010-10-26 | 동국제약 주식회사 | 신규한 몬테루카스트 4-할로 벤질아민염 및 이를 이용한 몬테루카스트 나트륨염의 제조방법 |
HUP1000425A2 (en) | 2010-08-11 | 2012-03-28 | Richter Gedeon Nyrt | Process for the production of montelukast sodium |
WO2012077133A1 (en) * | 2010-12-07 | 2012-06-14 | Ind-Swift Laboratories Limited | Processes for preparation of montelukast sodium and purification of diol intermediate |
CN102060762B (zh) * | 2011-01-28 | 2013-05-29 | 海南美大制药有限公司 | 孟鲁司特化合物及其新制法 |
CN103570618A (zh) * | 2013-09-30 | 2014-02-12 | 浙江车头制药股份有限公司 | 一种孟鲁司特钠盐的制备方法 |
CN105585524B (zh) * | 2016-02-29 | 2018-03-02 | 山东新时代药业有限公司 | 一种由孟鲁司特酸制备孟鲁司特钠的方法 |
CN105924392B (zh) * | 2016-02-29 | 2018-03-02 | 山东新时代药业有限公司 | 一种孟鲁司特钠制备方法 |
CN105646344B (zh) * | 2016-02-29 | 2018-08-14 | 山东新时代药业有限公司 | 一种孟鲁司特的纯化方法 |
US10723721B2 (en) * | 2017-07-24 | 2020-07-28 | Interquim, S.A. | Process for preparing and purifying the LFA-1 antagonist lifitegrast |
IT201800006337A1 (it) * | 2018-06-14 | 2019-12-14 | Procedimento per la preparazione di lifitegrast | |
AU2019334202A1 (en) | 2018-09-06 | 2021-03-25 | Innopharmascreen, Inc. | Methods and compositions for treatment of asthma or parkinson's disease |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8403224A (nl) * | 1984-10-24 | 1986-05-16 | Oce Andeno Bv | Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen. |
DK0480717T3 (da) * | 1990-10-12 | 1999-02-08 | Merck Frosst Canada Inc | Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister |
TW448160B (en) * | 1993-12-28 | 2001-08-01 | Merck & Co Inc | Novel dicyclohexylamine salt and process for the preparation of leukotriene antagonists |
CN1420113A (zh) | 2001-11-16 | 2003-05-28 | 北京上地新世纪生物医药研究所 | 孟鲁司特钠的制备方法及其制备中间体 |
CN1171873C (zh) | 2001-12-26 | 2004-10-20 | 北京上地新世纪生物医药研究所 | 一种孟鲁司特钠的制备方法及其制备中间体 |
US20050107612A1 (en) * | 2002-12-30 | 2005-05-19 | Dr. Reddy's Laboratories Limited | Process for preparation of montelukast and its salts |
ATE540926T1 (de) * | 2003-06-06 | 2012-01-15 | Morepen Lab Ltd | Verbessertes verfahren zur herstellung von montelukastsäure natriumsalz in amorpher form |
CA2541994A1 (en) * | 2003-10-10 | 2005-05-06 | Arjanne Overeem | Solid-state montelukast |
US20050187243A1 (en) * | 2004-01-30 | 2005-08-25 | Valerie Niddam-Hildesheim | Montelukast free acid polymorphs |
US7189853B2 (en) * | 2004-04-15 | 2007-03-13 | Dr. Reddy's Laboratories Limited | Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts |
ES2327762T3 (es) | 2004-04-21 | 2009-11-03 | Teva Pharmaceutical Industries Ltd | Procedimiento para preparar montelukast sodico. |
US7829716B2 (en) | 2004-04-30 | 2010-11-09 | Synthon Pharmaceuticals, Inc. | Process for making montelukast and intermediates therefor |
US7501517B2 (en) | 2004-04-30 | 2009-03-10 | Synthon Ip, Inc. | Process for making montelukast and intermediates therefor |
DE602004031678D1 (de) * | 2004-07-19 | 2011-04-14 | Matrix Lab Ltd | Verfahren zur herstellung von montelukast und salzen davon |
PL205637B1 (pl) * | 2004-10-22 | 2010-05-31 | Inst Farmaceutyczny | Sposób wytwarzania kwasu (R,E)-(1-{1-{3-[2-(7-chlorochinolin-2-ylo)etenylo]fenylo}-3-[2-(1-hydroksy-1-metyloetylo)fenylo] propylosulfanylometylo}cyklopropylo)octowego i/lub jego farmaceutycznie dopuszczalnych soli |
ATE497492T1 (de) | 2005-07-05 | 2011-02-15 | Teva Pharma | Reinigung von montelukast |
EP1940793A4 (en) | 2005-07-05 | 2011-03-23 | Matrix Lab Ltd | METHOD FOR PRODUCING MONTELUCASTS |
EP1912499A4 (en) | 2005-07-20 | 2010-03-31 | Reddys Lab Ltd Dr | PREPARATION OF MONTELUKAST |
US8178680B2 (en) | 2005-12-13 | 2012-05-15 | Msn Laboratories Limited | Process for the preparation of Montelukast and its pharmaceutically acceptable salts |
US20090182148A1 (en) | 2005-12-23 | 2009-07-16 | Harmander Singh Pal Chawla | Process for the manufacture of montelukast sodium |
WO2007096875A2 (en) | 2006-02-21 | 2007-08-30 | Chemagis Ltd. | Novel polymorphs of montelukast ammonium salts and processes for preparation therefor |
US7528254B2 (en) | 2006-02-27 | 2009-05-05 | Chemagis Ltd. | Process for preparing montelukast and salts thereof |
CN101432267A (zh) | 2006-03-17 | 2009-05-13 | 斯索恩有限公司 | 孟鲁司特金刚烷胺盐 |
WO2007116240A1 (en) | 2006-04-12 | 2007-10-18 | Glade Organics Private Limited | An improved process for the manufacture of montelukast sodium |
US20090326232A1 (en) | 2006-06-26 | 2009-12-31 | Uttam Kumar Ray | Process for the Preparation of Leukotriene Receptor Antagonist (Montelukast Sodium) |
GB0614485D0 (en) | 2006-07-21 | 2006-09-27 | Pliva Istrazivanje I Razvoj D | Process |
EP2069307A4 (en) | 2006-08-04 | 2010-03-03 | Matrix Lab Ltd | PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS |
-
2006
- 2006-08-09 EP EP06118690A patent/EP1886998A1/en not_active Withdrawn
-
2007
- 2007-08-07 AU AU2007283615A patent/AU2007283615A1/en not_active Abandoned
- 2007-08-07 PT PT07788281T patent/PT2077996E/pt unknown
- 2007-08-07 ZA ZA200900890A patent/ZA200900890B/xx unknown
- 2007-08-07 JP JP2009523276A patent/JP5188501B2/ja not_active Expired - Fee Related
- 2007-08-07 MX MX2009000524A patent/MX2009000524A/es active IP Right Grant
- 2007-08-07 WO PCT/EP2007/058180 patent/WO2008017669A1/en active Application Filing
- 2007-08-07 CN CN2007800295684A patent/CN101501000B/zh not_active Expired - Fee Related
- 2007-08-07 CA CA002657775A patent/CA2657775A1/en not_active Abandoned
- 2007-08-07 ES ES07788281T patent/ES2372414T3/es active Active
- 2007-08-07 US US12/376,779 patent/US8188285B2/en not_active Expired - Fee Related
- 2007-08-07 SI SI200730709T patent/SI2077996T1/sl unknown
- 2007-08-07 EP EP07788281A patent/EP2077996B1/en active Active
- 2007-08-07 PL PL07788281T patent/PL2077996T3/pl unknown
- 2007-08-07 AT AT07788281T patent/ATE515498T1/de not_active IP Right Cessation
- 2007-08-07 KR KR1020097002477A patent/KR20090035696A/ko not_active Application Discontinuation
- 2007-08-07 RU RU2009108272/04A patent/RU2009108272A/ru not_active Application Discontinuation
-
2008
- 2008-12-31 IL IL196303A patent/IL196303A/en not_active IP Right Cessation
-
2009
- 2009-03-09 NO NO20091051A patent/NO20091051L/no not_active Application Discontinuation
-
2011
- 2011-08-02 HR HR20110575T patent/HRP20110575T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CN101501000A (zh) | 2009-08-05 |
PL2077996T3 (pl) | 2011-11-30 |
JP5188501B2 (ja) | 2013-04-24 |
CN101501000B (zh) | 2012-04-04 |
IL196303A (en) | 2014-03-31 |
MX2009000524A (es) | 2009-01-27 |
EP2077996B1 (en) | 2011-07-06 |
WO2008017669A1 (en) | 2008-02-14 |
JP2010500325A (ja) | 2010-01-07 |
ES2372414T3 (es) | 2012-01-19 |
CA2657775A1 (en) | 2008-02-14 |
ATE515498T1 (de) | 2011-07-15 |
EP2077996A1 (en) | 2009-07-15 |
IL196303A0 (en) | 2009-09-22 |
RU2009108272A (ru) | 2010-09-20 |
KR20090035696A (ko) | 2009-04-10 |
US20090247759A1 (en) | 2009-10-01 |
SI2077996T1 (sl) | 2011-10-28 |
HRP20110575T1 (hr) | 2011-09-30 |
AU2007283615A1 (en) | 2008-02-14 |
ZA200900890B (en) | 2010-04-28 |
PT2077996E (pt) | 2011-09-13 |
EP1886998A1 (en) | 2008-02-13 |
US8188285B2 (en) | 2012-05-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |