NO20085257L - Purinonderivater som HM74a-agonister - Google Patents

Purinonderivater som HM74a-agonister

Info

Publication number
NO20085257L
NO20085257L NO20085257A NO20085257A NO20085257L NO 20085257 L NO20085257 L NO 20085257L NO 20085257 A NO20085257 A NO 20085257A NO 20085257 A NO20085257 A NO 20085257A NO 20085257 L NO20085257 L NO 20085257L
Authority
NO
Norway
Prior art keywords
purinone derivatives
hm74a agonists
agonists
purinone
derivatives
Prior art date
Application number
NO20085257A
Other languages
English (en)
Norwegian (no)
Inventor
Brian Metcalf
Anlai Wang
Chu-Biao Xue
Changsheng Zheng
Ganfeng Cao
Michael Xia
Hai Fen Ye
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of NO20085257L publication Critical patent/NO20085257L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20085257A 2006-06-23 2008-12-16 Purinonderivater som HM74a-agonister NO20085257L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81595506P 2006-06-23 2006-06-23
US92281807P 2007-04-11 2007-04-11
PCT/US2007/071891 WO2007150025A2 (en) 2006-06-23 2007-06-22 Purinone derivatives as hm74a agonists

Publications (1)

Publication Number Publication Date
NO20085257L true NO20085257L (no) 2009-01-19

Family

ID=38721463

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085257A NO20085257L (no) 2006-06-23 2008-12-16 Purinonderivater som HM74a-agonister

Country Status (14)

Country Link
US (4) US7511050B2 (zh)
EP (1) EP2044074A2 (zh)
JP (1) JP5584466B2 (zh)
KR (1) KR20090025261A (zh)
CN (1) CN101466714B (zh)
AR (1) AR061625A1 (zh)
AU (1) AU2007260851B2 (zh)
BR (1) BRPI0713619A2 (zh)
CA (1) CA2656039A1 (zh)
IL (1) IL195904A0 (zh)
MX (1) MX2009000170A (zh)
NO (1) NO20085257L (zh)
TW (1) TWI423977B (zh)
WO (1) WO2007150025A2 (zh)

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SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
CA2656002A1 (en) * 2006-06-23 2007-12-27 Incyte Corporation Purinone derivatives as hm74a agonists
KR20090025261A (ko) 2006-06-23 2009-03-10 인사이트 코포레이션 Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
KR101799429B1 (ko) * 2010-05-03 2017-11-21 에스케이바이오팜 주식회사 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en) 2011-09-27 2013-04-04 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
BR112019001459A2 (pt) 2016-07-27 2019-05-07 Hartis-Pharma Sa combinação, composição farmacêutica, e, método de prevenção e/ou de tratamento de uma doença ou de um distúrbio.
AR112457A1 (es) * 2017-08-02 2019-10-30 Lilly Co Eli Derivados de [1,2,4]triazolo[4,3-a]pirazin-6(5h)-ona
US11319324B2 (en) 2017-10-27 2022-05-03 Bayer Aktiengesellschaft Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors
CR20200441A (es) 2018-02-27 2021-03-15 Incyte Corp Imidazopirimidinas y triazolopirimidinas como inhibidores de a2a / a2b
US11220510B2 (en) 2018-04-09 2022-01-11 Incyte Corporation Pyrrole tricyclic compounds as A2A / A2B inhibitors
MX2020012376A (es) 2018-05-18 2021-03-09 Incyte Corp Derivados de pirimidina fusionados como inhibidores de los receptores de adenosina a2a/a2b.
TW202402759A (zh) 2018-07-05 2024-01-16 美商英塞特公司 作為a2a/a2b抑制劑之稠合吡嗪衍生物
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶

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BE863525A (fr) 1977-02-14 1978-07-31 Bristol Myers Co Heterocyclopyrimidines
US4404380A (en) * 1977-02-14 1983-09-13 Mead Johnson & Company Triazolopyrimidines
EP0425541A1 (en) * 1988-07-21 1991-05-08 The Upjohn Company Pyrazolo-azolo-pyrimidine-diones
ATE145908T1 (de) 1989-09-14 1996-12-15 Kyowa Hakko Kogyo Kk 5-triazolo(3,4-i)purinderivate
JPH083168A (ja) * 1994-06-15 1996-01-09 Yamasa Shoyu Co Ltd ４−メチル−９Ｈ−イミダゾ［１，２−ａ］プリン−９−オン類
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WO2006045564A1 (en) * 2004-10-22 2006-05-04 Smithkline Beecham Corporation Xanthine derivatives with hm74a receptor activity
RU2007118932A (ru) * 2004-10-22 2008-11-27 Смитклайн Бичам Корпорейшн (US) Производные ксантина с активностью нм74а
GB0516462D0 (en) 2005-08-10 2005-09-14 Smithkline Beecham Corp Novel compounds
EP1912992A1 (en) 2005-08-10 2008-04-23 SmithKline Beecham Corporation Xanthine derivatives as selective hm74a agonists
CA2656002A1 (en) 2006-06-23 2007-12-27 Incyte Corporation Purinone derivatives as hm74a agonists
KR20090025261A (ko) * 2006-06-23 2009-03-10 인사이트 코포레이션 Ｈｍ７４ａ 아고니스트로서의 퓨리논 유도체

Also Published As

Publication number Publication date
TWI423977B (zh) 2014-01-21
US20090286774A1 (en) 2009-11-19
TW200813064A (en) 2008-03-16
AU2007260851B2 (en) 2013-01-17
US20140371216A1 (en) 2014-12-18
WO2007150025A3 (en) 2008-02-07
US8039478B2 (en) 2011-10-18
CA2656039A1 (en) 2007-12-27
CN101466714A (zh) 2009-06-24
US20080045554A1 (en) 2008-02-21
AU2007260851A1 (en) 2007-12-27
KR20090025261A (ko) 2009-03-10
US8703783B2 (en) 2014-04-22
US20120035172A1 (en) 2012-02-09
JP5584466B2 (ja) 2014-09-03
WO2007150025A2 (en) 2007-12-27
IL195904A0 (en) 2009-09-01
EP2044074A2 (en) 2009-04-08
AR061625A1 (es) 2008-09-10
JP2009541355A (ja) 2009-11-26
BRPI0713619A2 (pt) 2013-01-15
MX2009000170A (es) 2009-01-23
CN101466714B (zh) 2013-02-06
US7511050B2 (en) 2009-03-31

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Legal Events

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