ATE145908T1 - 5-triazolo(3,4-i)purinderivate - Google Patents
5-triazolo(3,4-i)purinderivateInfo
- Publication number
- ATE145908T1 ATE145908T1 AT90117662T AT90117662T ATE145908T1 AT E145908 T1 ATE145908 T1 AT E145908T1 AT 90117662 T AT90117662 T AT 90117662T AT 90117662 T AT90117662 T AT 90117662T AT E145908 T1 ATE145908 T1 AT E145908T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- triazolo
- chem
- alkyl
- unsubstituted aryl
- Prior art date
Links
- 229940083251 peripheral vasodilators purine derivative Drugs 0.000 title 1
- 150000003212 purines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 239000011593 sulfur Substances 0.000 abstract 2
- RLTQUEBNOKLEIN-UHFFFAOYSA-N 9H-[1,2,4]triazolo[3,4-f]purine Chemical class N1=CN2C=NN=C2C2=C1N=CN2 RLTQUEBNOKLEIN-UHFFFAOYSA-N 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23911789 | 1989-09-14 | ||
| JP26176189 | 1989-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE145908T1 true ATE145908T1 (de) | 1996-12-15 |
Family
ID=26534087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90117662T ATE145908T1 (de) | 1989-09-14 | 1990-09-13 | 5-triazolo(3,4-i)purinderivate |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0417790B1 (de) |
| JP (1) | JP2980658B2 (de) |
| AT (1) | ATE145908T1 (de) |
| CA (1) | CA2025413C (de) |
| DE (1) | DE69029303T2 (de) |
| DK (1) | DK0417790T3 (de) |
| ES (1) | ES2097124T3 (de) |
| GR (1) | GR3022027T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5338743A (en) * | 1988-06-06 | 1994-08-16 | Fujisawa Pharmaceutical Co., Ltd. | New use of the adenosine antagonist |
| EP0423805B1 (de) * | 1989-10-20 | 2000-08-23 | Kyowa Hakko Kogyo Kabushiki Kaisha | Kondensierte Purinderivate |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| DE69531506T2 (de) | 1994-12-13 | 2004-06-24 | Euroceltique S.A. | Arylthioxanthine |
| US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) * | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| ES2166270B1 (es) | 1999-07-27 | 2003-04-01 | Almirall Prodesfarma Sa | Derivados de 8-fenil-6,9-dihidro-(1,2,4,)triazolo(3,4-i)purin-5-ona. |
| JP5274455B2 (ja) | 2006-06-23 | 2013-08-28 | インサイト コーポレイション | Ｈｍ７４ａアゴニストとしてのプリノン誘導体 |
| AU2007260851B2 (en) * | 2006-06-23 | 2013-01-17 | Incyte Corporation | Purinone derivatives as HM74a agonists |
| EP3735413B1 (de) | 2018-01-04 | 2022-07-06 | Impetis Biosciences Ltd. | Tricyclische verbindungen, zusammensetzungen und medizinische anwendungen davon |
| EP3845535B1 (de) * | 2018-08-30 | 2024-06-26 | Tera Stone Co., Ltd | Hydrazinopurinverbindung und triazolopurinverbindung zur hemmung von xanthinoxidase |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404380A (en) * | 1977-02-14 | 1983-09-13 | Mead Johnson & Company | Triazolopyrimidines |
-
1990
- 1990-09-13 JP JP2243248A patent/JP2980658B2/ja not_active Expired - Lifetime
- 1990-09-13 DE DE69029303T patent/DE69029303T2/de not_active Expired - Fee Related
- 1990-09-13 ES ES90117662T patent/ES2097124T3/es not_active Expired - Lifetime
- 1990-09-13 AT AT90117662T patent/ATE145908T1/de not_active IP Right Cessation
- 1990-09-13 EP EP90117662A patent/EP0417790B1/de not_active Expired - Lifetime
- 1990-09-13 DK DK90117662.8T patent/DK0417790T3/da active
- 1990-09-14 CA CA002025413A patent/CA2025413C/en not_active Expired - Fee Related
-
1996
- 1996-12-13 GR GR960403448T patent/GR3022027T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0417790A2 (de) | 1991-03-20 |
| GR3022027T3 (en) | 1997-03-31 |
| DK0417790T3 (da) | 1997-04-07 |
| JP2980658B2 (ja) | 1999-11-22 |
| CA2025413A1 (en) | 1991-03-15 |
| CA2025413C (en) | 1997-11-04 |
| EP0417790B1 (de) | 1996-12-04 |
| JPH03204879A (ja) | 1991-09-06 |
| DE69029303D1 (de) | 1997-01-16 |
| DE69029303T2 (de) | 1997-05-28 |
| ES2097124T3 (es) | 1997-04-01 |
| EP0417790A3 (en) | 1992-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |