NO20085257L - Purinonderivater som HM74a-agonister - Google Patents
Purinonderivater som HM74a-agonisterInfo
- Publication number
- NO20085257L NO20085257L NO20085257A NO20085257A NO20085257L NO 20085257 L NO20085257 L NO 20085257L NO 20085257 A NO20085257 A NO 20085257A NO 20085257 A NO20085257 A NO 20085257A NO 20085257 L NO20085257 L NO 20085257L
- Authority
- NO
- Norway
- Prior art keywords
- purinone derivatives
- hm74a agonists
- agonists
- purinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Foreliggende oppfinnelse angår purinonderivater som er agonister av HM74areseptoren. Videre tilveiebringes det preparater og metoder for anvendelse av forbindelsene her og deres farmasøytisk akseptable salter for behandling av sykdom.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81595506P | 2006-06-23 | 2006-06-23 | |
US92281807P | 2007-04-11 | 2007-04-11 | |
PCT/US2007/071891 WO2007150025A2 (en) | 2006-06-23 | 2007-06-22 | Purinone derivatives as hm74a agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20085257L true NO20085257L (no) | 2009-01-19 |
Family
ID=38721463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20085257A NO20085257L (no) | 2006-06-23 | 2008-12-16 | Purinonderivater som HM74a-agonister |
Country Status (14)
Country | Link |
---|---|
US (4) | US7511050B2 (no) |
EP (1) | EP2044074A2 (no) |
JP (1) | JP5584466B2 (no) |
KR (1) | KR20090025261A (no) |
CN (1) | CN101466714B (no) |
AR (1) | AR061625A1 (no) |
AU (1) | AU2007260851B2 (no) |
BR (1) | BRPI0713619A2 (no) |
CA (1) | CA2656039A1 (no) |
IL (1) | IL195904A0 (no) |
MX (1) | MX2009000170A (no) |
NO (1) | NO20085257L (no) |
TW (1) | TWI423977B (no) |
WO (1) | WO2007150025A2 (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0302756D0 (sv) * | 2003-10-17 | 2003-10-17 | Astrazeneca Ab | Novel Compounds |
TWI423977B (zh) | 2006-06-23 | 2014-01-21 | Incyte Corp | 作為hm74a同效劑之嘌呤酮衍生物(一) |
JP5274455B2 (ja) * | 2006-06-23 | 2013-08-28 | インサイト コーポレイション | Hm74aアゴニストとしてのプリノン誘導体 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
KR101799429B1 (ko) * | 2010-05-03 | 2017-11-21 | 에스케이바이오팜 주식회사 | 신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물 |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
CA3032229A1 (en) | 2016-07-27 | 2018-02-01 | Hartis-Pharma Sa | Therapeutic combinations to treat red blood cell disorders |
AR112457A1 (es) * | 2017-08-02 | 2019-10-30 | Lilly Co Eli | Derivados de [1,2,4]triazolo[4,3-a]pirazin-6(5h)-ona |
MX2020004981A (es) | 2017-10-27 | 2020-08-24 | Bayer Ag | Novedosos derivados de pirazolo-pirrolo-pirimidina como inhibidores de p2x3. |
US20190292188A1 (en) | 2018-02-27 | 2019-09-26 | Incyte Corporation | Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors |
US11220510B2 (en) | 2018-04-09 | 2022-01-11 | Incyte Corporation | Pyrrole tricyclic compounds as A2A / A2B inhibitors |
MX2020012376A (es) | 2018-05-18 | 2021-03-09 | Incyte Corp | Derivados de pirimidina fusionados como inhibidores de los receptores de adenosina a2a/a2b. |
AU2019297361A1 (en) | 2018-07-05 | 2021-02-25 | Incyte Corporation | Fused pyrazine derivatives as A2A / A2B inhibitors |
TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE863525A (fr) | 1977-02-14 | 1978-07-31 | Bristol Myers Co | Heterocyclopyrimidines |
CA1095906A (en) * | 1977-02-14 | 1981-02-17 | Davis L. Temple, Jr. | Heterocyclopyrimidines, compositions and therapeutic process |
US4404380A (en) * | 1977-02-14 | 1983-09-13 | Mead Johnson & Company | Triazolopyrimidines |
EP0425541A1 (en) * | 1988-07-21 | 1991-05-08 | The Upjohn Company | Pyrazolo-azolo-pyrimidine-diones |
DE69029303T2 (de) * | 1989-09-14 | 1997-05-28 | Kyowa Hakko Kogyo Kk | 5-Triazolo(3,4-i)purinderivate |
JPH083168A (ja) * | 1994-06-15 | 1996-01-09 | Yamasa Shoyu Co Ltd | 4−メチル−9H−イミダゾ[1,2−a]プリン−9−オン類 |
JP3204879B2 (ja) | 1995-08-04 | 2001-09-04 | オリエンタル酵母工業株式会社 | パン用酵母の包装紙 |
EP0879183A1 (fr) | 1996-07-18 | 1998-11-25 | Montania | Bouchon avec recipient auxiliaire et procede de realisation |
DE19629378A1 (de) | 1996-07-20 | 1998-01-29 | Boehringer Ingelheim Kg | Neue Triazolopurine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
AU7966098A (en) | 1997-06-12 | 1998-12-30 | Smithkline Beecham Corporation | Hm74a receptor |
EP1092435B1 (en) | 1998-07-02 | 2007-04-04 | Kyowa Hakko Kogyo Co., Ltd. | Remedies for diabetes |
AU2223501A (en) | 1999-12-24 | 2001-07-09 | Kyowa Hakko Kogyo Co. Ltd. | Fused purine derivatives |
AU1560802A (en) | 2000-06-28 | 2002-01-08 | Smithkline Beecham Plc | Wet milling process |
BR0115833A (pt) | 2000-12-01 | 2003-10-28 | Biogen Inc | Derivados condensados de purina como antagonistas de receptores de adenosina a1 |
WO2002084298A2 (en) | 2001-04-11 | 2002-10-24 | Glaxo Group Limited | Medicaments which are modulators of hm74 and/or hm74a activity |
UA80258C2 (en) | 2001-09-06 | 2007-09-10 | Biogen Inc | Methods of treating pulmonary disease |
US6902902B2 (en) | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
US7465548B2 (en) | 2003-02-17 | 2008-12-16 | Bayer Healthcare Ag | Methods of screening for potential therapeutics for diseases associated with G-protein coupled receptor HM74a |
KR101100601B1 (ko) | 2004-02-14 | 2011-12-29 | 글락소스미스클라인 엘엘씨 | 신규 화합물 |
US20050205364A1 (en) | 2004-03-12 | 2005-09-22 | Browne Alan L | Variable resistance strut assemblies and articles containing the same |
US7267695B2 (en) | 2004-06-25 | 2007-09-11 | American Prosthetic Components, Inc. | Four hole offset alignment device |
WO2006021892A2 (en) | 2004-08-27 | 2006-03-02 | Endocube S.A.S. | Hm74 and hm74a in cuboidal endothelial cells as associated with inflammation |
WO2006045565A1 (en) * | 2004-10-22 | 2006-05-04 | Smithkline Beecham Corporation | Xanthine derivatives with hm74a receptor activity |
WO2006045564A1 (en) * | 2004-10-22 | 2006-05-04 | Smithkline Beecham Corporation | Xanthine derivatives with hm74a receptor activity |
GB0516462D0 (en) | 2005-08-10 | 2005-09-14 | Smithkline Beecham Corp | Novel compounds |
JP2009504592A (ja) | 2005-08-10 | 2009-02-05 | スミスクライン・ビーチャム・コーポレイション | 選択的hm74aアゴニストとしてのキサンチン誘導体 |
TWI423977B (zh) | 2006-06-23 | 2014-01-21 | Incyte Corp | 作為hm74a同效劑之嘌呤酮衍生物(一) |
JP5274455B2 (ja) | 2006-06-23 | 2013-08-28 | インサイト コーポレイション | Hm74aアゴニストとしてのプリノン誘導体 |
-
2007
- 2007-06-22 TW TW096122480A patent/TWI423977B/zh not_active IP Right Cessation
- 2007-06-22 BR BRPI0713619-6A patent/BRPI0713619A2/pt not_active IP Right Cessation
- 2007-06-22 MX MX2009000170A patent/MX2009000170A/es active IP Right Grant
- 2007-06-22 US US11/766,981 patent/US7511050B2/en active Active
- 2007-06-22 CA CA002656039A patent/CA2656039A1/en not_active Abandoned
- 2007-06-22 AU AU2007260851A patent/AU2007260851B2/en not_active Ceased
- 2007-06-22 KR KR1020087031335A patent/KR20090025261A/ko active IP Right Grant
- 2007-06-22 CN CN2007800221892A patent/CN101466714B/zh not_active Expired - Fee Related
- 2007-06-22 AR ARP070102782A patent/AR061625A1/es not_active Application Discontinuation
- 2007-06-22 WO PCT/US2007/071891 patent/WO2007150025A2/en active Application Filing
- 2007-06-22 EP EP07798937A patent/EP2044074A2/en not_active Withdrawn
- 2007-06-22 JP JP2009516748A patent/JP5584466B2/ja not_active Expired - Fee Related
-
2008
- 2008-11-03 US US12/263,990 patent/US8039478B2/en not_active Expired - Fee Related
- 2008-12-11 IL IL195904A patent/IL195904A0/en unknown
- 2008-12-16 NO NO20085257A patent/NO20085257L/no not_active Application Discontinuation
-
2011
- 2011-10-17 US US13/275,214 patent/US8703783B2/en active Active
-
2014
- 2014-04-18 US US14/256,350 patent/US20140371216A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US8039478B2 (en) | 2011-10-18 |
CA2656039A1 (en) | 2007-12-27 |
US20140371216A1 (en) | 2014-12-18 |
AU2007260851A1 (en) | 2007-12-27 |
CN101466714B (zh) | 2013-02-06 |
US20080045554A1 (en) | 2008-02-21 |
EP2044074A2 (en) | 2009-04-08 |
JP5584466B2 (ja) | 2014-09-03 |
BRPI0713619A2 (pt) | 2013-01-15 |
WO2007150025A2 (en) | 2007-12-27 |
US7511050B2 (en) | 2009-03-31 |
KR20090025261A (ko) | 2009-03-10 |
AU2007260851B2 (en) | 2013-01-17 |
US8703783B2 (en) | 2014-04-22 |
US20090286774A1 (en) | 2009-11-19 |
WO2007150025A3 (en) | 2008-02-07 |
TWI423977B (zh) | 2014-01-21 |
CN101466714A (zh) | 2009-06-24 |
AR061625A1 (es) | 2008-09-10 |
JP2009541355A (ja) | 2009-11-26 |
TW200813064A (en) | 2008-03-16 |
IL195904A0 (en) | 2009-09-01 |
MX2009000170A (es) | 2009-01-23 |
US20120035172A1 (en) | 2012-02-09 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |