NO20083171L - Ny samling av HCDR3 omrader og anvendelser derav - Google Patents

Ny samling av HCDR3 omrader og anvendelser derav

Info

Publication number
NO20083171L
NO20083171L NO20083171A NO20083171A NO20083171L NO 20083171 L NO20083171 L NO 20083171L NO 20083171 A NO20083171 A NO 20083171A NO 20083171 A NO20083171 A NO 20083171A NO 20083171 L NO20083171 L NO 20083171L
Authority
NO
Norway
Prior art keywords
hcdr3
collection
present
members
antibody
Prior art date
Application number
NO20083171A
Other languages
English (en)
Norwegian (no)
Inventor
Christine Rothe
Markus Enzelberger
Stefanie Thiel
Josef Prassler
Stefanie Urlinger
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of NO20083171L publication Critical patent/NO20083171L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20083171A 2005-12-20 2008-07-18 Ny samling av HCDR3 omrader og anvendelser derav NO20083171L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75163305P 2005-12-20 2005-12-20
PCT/IB2006/004301 WO2008053275A2 (fr) 2005-12-20 2006-12-15 Nouvel ensemble de régions hcdr3 et leurs utilisations

Publications (1)

Publication Number Publication Date
NO20083171L true NO20083171L (no) 2008-08-27

Family

ID=39273832

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083171A NO20083171L (no) 2005-12-20 2008-07-18 Ny samling av HCDR3 omrader og anvendelser derav

Country Status (15)

Country Link
US (1) US8273688B2 (fr)
EP (1) EP1979378B1 (fr)
JP (1) JP5405831B2 (fr)
KR (1) KR20080080653A (fr)
CN (1) CN101389655B (fr)
AU (1) AU2006350452B2 (fr)
CA (1) CA2634387C (fr)
DK (1) DK1979378T3 (fr)
ES (1) ES2394722T3 (fr)
IL (1) IL192315A0 (fr)
MX (1) MX2008008220A (fr)
NO (1) NO20083171L (fr)
NZ (1) NZ569359A (fr)
WO (1) WO2008053275A2 (fr)
ZA (1) ZA200806016B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
US20030133939A1 (en) * 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) * 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
PT2298815E (pt) * 2005-07-25 2015-07-16 Emergent Product Dev Seattle Moléculas de ligaçao especificas para cd37 e especificas para cd20
MX2008015524A (es) * 2006-06-12 2009-01-13 Trubion Pharmaceuticals Inc Proteinas de union multivalentes monocatenarias con funcion efectora.
US8691730B2 (en) 2007-09-14 2014-04-08 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
EP2098536A1 (fr) 2008-03-05 2009-09-09 4-Antibody AG Isolation et identification de protéines de liaison spécifiques à des antigènes ou à des ligands
WO2009114815A1 (fr) 2008-03-13 2009-09-17 Dyax Corp Bibliothèques de boîtiers génétiques comprenant de nouvelles conceptions de hc cdr3
WO2009126944A1 (fr) 2008-04-11 2009-10-15 Trubion Pharmaceuticals, Inc. Produits d’immunothérapie de cd37 et combinaison avec un produit chimiothérapique bifonctionnel de celui-ci
ES2528963T3 (es) 2008-04-24 2015-02-13 Dyax Corp. Bibliotecas de paquetes genéticos que comprenden nuevos diseños de CDR1, CDR2, y CDR3 de HC y nuevos diseños de CDR1, CDR2, y CDR3 de LC
MX2011012696A (es) 2009-05-29 2012-03-29 Morphosys Ag Una coleccion y metodos para su uso.
WO2011032181A2 (fr) * 2009-09-14 2011-03-17 Dyax Corp. Bibliothèques d'ensembles génétiques comprenant de nouvelles conceptions de hc cdr3
CN105734678B (zh) 2010-07-16 2019-11-05 阿迪马布有限责任公司 合成多核苷酸文库
SG189950A1 (en) 2010-11-19 2013-06-28 Morphosys Ag A collection and methods for its use
MY197562A (en) 2015-09-21 2023-06-23 Aptevo Res & Development Llc Cd3 binding polypeptides
CN105274630A (zh) * 2015-11-25 2016-01-27 苏州泓迅生物科技有限公司 基于组合合成技术合成可控的人源化抗体库的方法与应用
JP6959260B2 (ja) * 2016-01-19 2021-11-02 ズムトール バイオロジクス、インコーポレイテッド 合成抗体ライブラリーを作製する方法、前記ライブラリー、及びその適用
EP3293293A1 (fr) 2016-09-08 2018-03-14 Italfarmaco SpA Bibliothèques uniquement de hc-cdr3-avec redondance combinatoire réduite et distribution de longueur de boucle optimisée

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706484B1 (en) * 1995-08-18 2004-03-16 Morphosys Ag Protein/(poly)peptide libraries
JP4436457B2 (ja) * 1995-08-18 2010-03-24 モルフォシス アイピー ゲーエムベーハー 蛋白質／（ポリ）ペプチドライブラリー
DE60041119D1 (de) * 1999-07-20 2009-01-29 Morphosys Ag Verfahren zur präsentation von (poly)peptiden/proteinen auf bakteriophagenpartikeln via disulfidbindungen
PT2316940E (pt) * 2000-12-18 2013-10-16 Dyax Corp Bibliotecas orientadas de pacotes genéticos

Also Published As

Publication number Publication date
US8273688B2 (en) 2012-09-25
AU2006350452B2 (en) 2012-10-25
MX2008008220A (es) 2009-03-04
CN101389655A (zh) 2009-03-18
DK1979378T3 (da) 2012-10-29
EP1979378A2 (fr) 2008-10-15
CA2634387A1 (fr) 2008-05-08
ES2394722T3 (es) 2013-02-05
JP2009519727A (ja) 2009-05-21
KR20080080653A (ko) 2008-09-04
IL192315A0 (en) 2008-12-29
CN101389655B (zh) 2013-05-22
JP5405831B2 (ja) 2014-02-05
EP1979378B1 (fr) 2012-07-25
AU2006350452A1 (en) 2008-05-08
WO2008053275A3 (fr) 2008-08-21
ZA200806016B (en) 2009-07-29
CA2634387C (fr) 2015-11-24
WO2008053275A2 (fr) 2008-05-08
NZ569359A (en) 2011-11-25
US20090088346A1 (en) 2009-04-02

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