NO20082816L - Farmasoytikum for anvendelse ved behandling av ureterolitiasis - Google Patents

Farmasoytikum for anvendelse ved behandling av ureterolitiasis

Info

Publication number
NO20082816L
NO20082816L NO20082816A NO20082816A NO20082816L NO 20082816 L NO20082816 L NO 20082816L NO 20082816 A NO20082816 A NO 20082816A NO 20082816 A NO20082816 A NO 20082816A NO 20082816 L NO20082816 L NO 20082816L
Authority
NO
Norway
Prior art keywords
cyano
carbamoyl
substituent
lower alkyl
aryl
Prior art date
Application number
NO20082816A
Other languages
English (en)
Inventor
Mamoru Kobayashi
Yoshitaka Tomiyama
Kumi Kobayashi
Original Assignee
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical filed Critical Kissei Pharmaceutical
Publication of NO20082816L publication Critical patent/NO20082816L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Den foreliggende oppfinnelsen fremskaffer legemiddelblandinger som er nyttige for å lindre smerte som er forårsaket av uretersten idet de gjør det lettere for steinen å komme ut eller lignende. Det vil si at den foreliggende oppfinnelsen fremskaffer en legemiddelblanding til behandling av uretersten som inneholder et indolinderivat som et aktivt virkestoff som er representert ved følgende generelle formel (I) eller et salt av dette. I formelen representerer R mettet eller umettet alifatisk acyl som kan ha en substituent; hydroksyalkyl; alifatisk acyloksyalkyl; lavere alkyl som har som en substituent lavere alkoksy, karboksy, lavere alkoksykarbonyl, aryl-substituert lavere alkoksykarbonyl, karbamoyl, mono eller di(lavere alkyl)-substituert karbamoyl eller cyano; valgfritt substituert aromatisk acyl; furoyl eller pyridylkarbonyl; R1 representerer cyano eller karbamoyl; og R2 representerer lavere alkyl som kan ha som en substituent halogen, cyano eller aryl.
NO20082816A 2005-11-24 2008-06-24 Farmasoytikum for anvendelse ved behandling av ureterolitiasis NO20082816L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005339188 2005-11-24
PCT/JP2006/323280 WO2007060974A1 (ja) 2005-11-24 2006-11-22 尿管結石症の治療用医薬

Publications (1)

Publication Number Publication Date
NO20082816L true NO20082816L (no) 2008-08-13

Family

ID=38067199

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082816A NO20082816L (no) 2005-11-24 2008-06-24 Farmasoytikum for anvendelse ved behandling av ureterolitiasis

Country Status (13)

Country Link
US (2) US20090163571A1 (no)
EP (1) EP1956001A4 (no)
JP (1) JP4865724B2 (no)
KR (1) KR101232425B1 (no)
CN (1) CN101336230B (no)
BR (1) BRPI0618996A2 (no)
CA (1) CA2628476C (no)
EA (1) EA016008B1 (no)
HK (1) HK1125634A1 (no)
NO (1) NO20082816L (no)
TW (1) TW200803843A (no)
UA (1) UA92765C2 (no)
WO (1) WO2007060974A1 (no)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2132254T3 (es) * 1992-09-14 1999-08-16 Forssmann Wolf Georg Prof Dr Nueva utilizacion de inhibidores de la fosfodiesterasa iv.
EP0600675B1 (en) * 1992-12-02 1998-07-08 Kissei Pharmaceutical Co., Ltd. Indoline compounds for the treatment of dysuria
JP4324266B2 (ja) * 1999-02-26 2009-09-02 キッセイ薬品工業株式会社 α１Ａアドレナリン受容体の変異体、当該変異体を用いた測定方法及び前立腺肥大に伴う排尿困難症治療剤
BR0116662A (pt) * 2001-01-02 2003-09-23 Hoffmann La Roche Derivados de quinazolona como antagonistas receptores alfa 1a/b adrenérgicos
JP2001288115A (ja) * 2001-02-07 2001-10-16 Yamanouchi Pharmaceut Co Ltd 下部尿路症治療剤
US20040072551A1 (en) * 2002-10-10 2004-04-15 Sanford John Richard Communication device with front-end integration

Also Published As

Publication number Publication date
BRPI0618996A2 (pt) 2011-09-20
EP1956001A1 (en) 2008-08-13
HK1125634A1 (en) 2009-08-14
US20110230538A1 (en) 2011-09-22
EA200801420A1 (ru) 2009-02-27
TW200803843A (en) 2008-01-16
KR101232425B1 (ko) 2013-02-12
US20090163571A1 (en) 2009-06-25
WO2007060974A1 (ja) 2007-05-31
EP1956001A4 (en) 2012-12-26
CN101336230B (zh) 2011-11-23
CA2628476A1 (en) 2007-05-31
KR20080071603A (ko) 2008-08-04
JPWO2007060974A1 (ja) 2009-05-07
CA2628476C (en) 2013-10-15
UA92765C2 (ru) 2010-12-10
CN101336230A (zh) 2008-12-31
EA016008B1 (ru) 2012-01-30
TWI379680B (no) 2012-12-21
JP4865724B2 (ja) 2012-02-01

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application