NO20082741L - Terapeutisk bruk av steroidale forbindelser - Google Patents

Terapeutisk bruk av steroidale forbindelser

Info

Publication number
NO20082741L
NO20082741L NO20082741A NO20082741A NO20082741L NO 20082741 L NO20082741 L NO 20082741L NO 20082741 A NO20082741 A NO 20082741A NO 20082741 A NO20082741 A NO 20082741A NO 20082741 L NO20082741 L NO 20082741L
Authority
NO
Norway
Prior art keywords
hydroxy
androstene
dione
disease
prevention
Prior art date
Application number
NO20082741A
Other languages
English (en)
Inventor
James Robert Murray
Ernst Wulfert
David Wynick
Original Assignee
Hunter Fleming Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunter Fleming Ltd filed Critical Hunter Fleming Ltd
Publication of NO20082741L publication Critical patent/NO20082741L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

En steroidderivatforbindelse med formel (I):hvor: én av Rog Rer hydroksy og den andre er hydrogen; eller1 og Rbetegner sammen okso; Rer hydrogen eller hydroksy; og de stiplede linjer betegner enkle eller doble karbon-karbon-bindinger; og farmasøytisk akseptable salter og estere derav er anvendbare til forebygging eller behandling av smerte, til forbedring av nerveregenerering etter nerveskade eller - sykdom, til forebygging eller behandling av hjerneskade eller -sykdom og for nevrobeskyttelse. Særlig anvendbare forbindelser er 1 l-hydroksy-A4-androsten-3,17-dion og 1 l-okso-A4-androsten-3,17-dion eller deres derivater.
NO20082741A 2005-11-18 2008-06-17 Terapeutisk bruk av steroidale forbindelser NO20082741L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0523550.2A GB0523550D0 (en) 2005-11-18 2005-11-18 Therapeutic uses of steroidal compounds
PCT/GB2006/004305 WO2007057691A2 (en) 2005-11-18 2006-11-17 Therapeutic uses of steroidal compounds

Publications (1)

Publication Number Publication Date
NO20082741L true NO20082741L (no) 2008-07-23

Family

ID=35580318

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20082741A NO20082741L (no) 2005-11-18 2008-06-17 Terapeutisk bruk av steroidale forbindelser

Country Status (16)

Country Link
US (1) US8846652B2 (no)
EP (1) EP1948192A2 (no)
JP (1) JP5395437B2 (no)
KR (1) KR101314694B1 (no)
CN (1) CN101346144B (no)
AU (1) AU2006314226B2 (no)
CA (1) CA2630441C (no)
GB (1) GB0523550D0 (no)
IL (1) IL191457A (no)
MX (1) MX2008006440A (no)
NO (1) NO20082741L (no)
NZ (1) NZ568560A (no)
RU (1) RU2427375C2 (no)
TW (1) TWI386211B (no)
WO (1) WO2007057691A2 (no)
ZA (1) ZA200804266B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU20110244A7 (es) 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
CN108434090A (zh) * 2017-02-14 2018-08-24 高药品股份有限公司 以生理脂肪为基剂的类固醇药膏
RU2745868C9 (ru) * 2020-05-28 2021-04-08 Федеральное государственное бюджетное образовательное учреждение высшего образования «Национальный исследовательский Мордовский государственный университет им. Н.П. Огарёва» Способ ускорения регенерационных процессов в поврежденных периферических нервах

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1350792A (en) 1991-01-16 1992-08-27 General Hospital Corporation, The Human galanin
WO1992015015A1 (en) 1991-02-25 1992-09-03 Zymogenetic, Inc. Methods for detecting galanin antagonists
WO1992015681A1 (en) 1991-03-06 1992-09-17 Garvan Institute Of Medical Research HUMAN GALANIN, cDNA CLONES ENCODING HUMAN GALANIN AND A METHOD OF PRODUCING HUMAN GALANIN
SE9101472D0 (sv) 1991-05-15 1991-05-15 Trion Forskning & Utveckling Galanin antagonist
JPH06172387A (ja) 1992-12-11 1994-06-21 Aibaitsu Kk 合成ペプチド誘導体
EP0698612B1 (en) * 1993-05-18 2001-07-25 Ltt Institute Co., Ltd. Osteogenesis promoter and osteoporosis remedy
JPH09151197A (ja) * 1995-11-29 1997-06-10 L T T Kenkyusho:Kk 自己免疫疾患治療薬
JP2000516212A (ja) 1996-07-24 2000-12-05 ユニバーシティー オブ ブリストル ガラニン
JP2000169374A (ja) * 1998-12-03 2000-06-20 Ltt Kenkyusho:Kk Ｉｇｆ増強剤
MXPA01012769A (es) 1999-06-11 2003-06-24 Watson Pharmaceuticals Inc Administracion de esteroides androgenicos no orales para mujeres.
GB0105772D0 (en) * 2001-03-08 2001-04-25 Sterix Ltd Use
DK1243262T3 (da) 2001-03-20 2006-10-02 Sanol Arznei Schwarz Gmbh Hidtil ukendt anvendelse af en peptidklasse af forbindelser til behandling af ikke-neuropatiske, inflammatoriske smerter
WO2002096934A1 (en) 2001-05-25 2002-12-05 Kemia, Inc. Non-natural galanin receptor ligands
CN101669933A (zh) 2001-07-16 2010-03-17 奥索-麦克尼尔药品公司 用于预防或治疗神经性疼痛和丛集性头痛及偏头痛性疼痛的氨基甲酸酯化合物
US20030087965A1 (en) 2001-07-31 2003-05-08 Robertson David W. Treatment of chronic pain with 3-aryloxy-3-phenylpropanamines
WO2003011289A1 (en) 2001-07-31 2003-02-13 Pharmacia + Upjohn Company Treatment of chronic pain with 3-heterocyclyl- and 3-cycloalkyl-3-aryloxypropanamines
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US20070231373A1 (en) * 2004-04-28 2007-10-04 Hunter-Fleming Limited Transdermal Steriod for Formulation
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KR20090086272A (ko) 2006-11-30 2009-08-11 헌터-플레밍 리미티드 프로스타글란딘／시클로옥시게나제 대사 경로의 조절

Also Published As

Publication number Publication date
CA2630441A1 (en) 2007-05-24
GB0523550D0 (en) 2005-12-28
WO2007057691A3 (en) 2007-08-02
EP1948192A2 (en) 2008-07-30
CN101346144A (zh) 2009-01-14
CN101346144B (zh) 2011-07-20
IL191457A0 (en) 2009-08-03
JP2009515939A (ja) 2009-04-16
CA2630441C (en) 2013-10-29
AU2006314226B2 (en) 2012-02-02
NZ568560A (en) 2010-11-26
AU2006314226A1 (en) 2007-05-24
ZA200804266B (en) 2009-01-28
MX2008006440A (es) 2008-12-01
RU2008124834A (ru) 2009-12-27
US8846652B2 (en) 2014-09-30
JP5395437B2 (ja) 2014-01-22
KR101314694B1 (ko) 2013-10-07
TW200730180A (en) 2007-08-16
TWI386211B (zh) 2013-02-21
US20090227551A1 (en) 2009-09-10
WO2007057691A2 (en) 2007-05-24
IL191457A (en) 2013-10-31
RU2427375C2 (ru) 2011-08-27
KR20080073755A (ko) 2008-08-11

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