NO20076691L - Nanopartikulaere imatinib-mesylatformuleringer - Google Patents
Nanopartikulaere imatinib-mesylatformuleringerInfo
- Publication number
- NO20076691L NO20076691L NO20076691A NO20076691A NO20076691L NO 20076691 L NO20076691 L NO 20076691L NO 20076691 A NO20076691 A NO 20076691A NO 20076691 A NO20076691 A NO 20076691A NO 20076691 L NO20076691 L NO 20076691L
- Authority
- NO
- Norway
- Prior art keywords
- imatinib mesylate
- nanoparticulate
- composition
- nanoparticulate imatinib
- mesylate formulations
- Prior art date
Links
- 229960003685 imatinib mesylate Drugs 0.000 title abstract 3
- YLMAHDNUQAMNNX-UHFFFAOYSA-N imatinib methanesulfonate Chemical compound CS(O)(=O)=O.C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 YLMAHDNUQAMNNX-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 abstract 1
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 abstract 1
- 206010051066 Gastrointestinal stromal tumour Diseases 0.000 abstract 1
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68714605P | 2005-06-03 | 2005-06-03 | |
| PCT/US2006/021657 WO2006133046A2 (fr) | 2005-06-03 | 2006-06-05 | Formulations d'imatinib mesylate nanoparticulaires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20076691L true NO20076691L (no) | 2008-02-25 |
Family
ID=37498974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076691A NO20076691L (no) | 2005-06-03 | 2007-12-28 | Nanopartikulaere imatinib-mesylatformuleringer |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060275372A1 (fr) |
| EP (1) | EP1895984B8 (fr) |
| JP (1) | JP2008542397A (fr) |
| KR (1) | KR20080017067A (fr) |
| CN (1) | CN101232870A (fr) |
| AT (1) | ATE459341T1 (fr) |
| AU (1) | AU2006255177A1 (fr) |
| BR (1) | BRPI0613540A2 (fr) |
| CA (1) | CA2610448A1 (fr) |
| DE (1) | DE602006012671D1 (fr) |
| EA (2) | EA015102B1 (fr) |
| ES (1) | ES2341996T3 (fr) |
| HK (1) | HK1118467A1 (fr) |
| IL (1) | IL187841A0 (fr) |
| MX (1) | MX2007015309A (fr) |
| NO (1) | NO20076691L (fr) |
| WO (1) | WO2006133046A2 (fr) |
| ZA (1) | ZA200710763B (fr) |
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| BRPI0602338A (pt) * | 2006-03-24 | 2007-12-11 | Univ Kyushu Nat Univ Corp | compostos orgánicos |
| US20060223817A1 (en) * | 2006-05-15 | 2006-10-05 | Chemagis Ltd. | Crystalline imatinib base and production process therefor |
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| WO2008027600A2 (fr) * | 2006-09-01 | 2008-03-06 | Teva Pharmaceutical Industries Ltd. | Compositions d'imatinib |
| US8466154B2 (en) | 2006-10-27 | 2013-06-18 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to wrapping of dehydrons |
| EP1920767A1 (fr) * | 2006-11-09 | 2008-05-14 | Abbott GmbH & Co. KG | Forme posologique d'Imatinib préparée à l'état fondu. |
| US20080293648A1 (en) * | 2007-01-05 | 2008-11-27 | Saha Pharmaceuticals, Inc. | Compositions and Methods for Cancer Treatment |
| BRPI0808840A2 (pt) * | 2007-03-12 | 2014-09-02 | Reddy S Laborartories Ltd Dr | Mesilato de imatinib |
| US20080234286A1 (en) * | 2007-03-20 | 2008-09-25 | Chemagis Ltd. | Stable amorphous imatinib mesylate and production process therefor |
| AU2012201613B2 (en) * | 2007-06-07 | 2014-12-04 | Novartis Ag | Stabilized amorphous forms of Imatinib mesylate |
| EP2305263B1 (fr) * | 2007-06-07 | 2012-09-19 | Novartis AG | Formes amorphes stabilisées du mésylate de l'imatinib |
| US20090087489A1 (en) * | 2007-09-25 | 2009-04-02 | Bella Gerber | Imatinib compositions |
| ITRM20080684A1 (it) * | 2008-12-19 | 2010-06-20 | Giovanni Cesareni | Uso di inibitori della tirosin chinasi c-abl per la preservazione degli oociti. |
| AU2010254180B2 (en) | 2009-05-27 | 2015-08-27 | Alkermes Pharma Ireland Limited | Reduction of flake-like aggregation in nanoparticulate active agent compositions |
| WO2011161689A1 (fr) * | 2010-06-21 | 2011-12-29 | Suven Nishtaa Pharma Pvt Ltd | Comprimé pharmaceutique de mésylate d'imatinib |
| TR201010618A2 (tr) * | 2010-12-20 | 2012-07-23 | Bi̇lgi̇ç Mahmut | İmatinib içeren bir oral dozaj formu ve bu oral dozaj formunun üretimi |
| US9750700B2 (en) * | 2011-06-22 | 2017-09-05 | Natco Pharma Limited | Imatinib mesylate oral pharmaceutical composition and process for preparation thereof |
| WO2013008253A2 (fr) * | 2011-07-11 | 2013-01-17 | Dr. Reddys Laboratories Limited | Formulations d'imatinib |
| EP2782560A1 (fr) * | 2011-11-24 | 2014-10-01 | Imuneks Farma Ilaç Sanayi Ve Ticaret A.S. | Formes posologiques solides à base d'imatinib reconstituées juste avant l'utilisation |
| EP2817030A1 (fr) | 2012-02-21 | 2014-12-31 | Ranbaxy Laboratories Limited | Formes posologiques stables de mésylate d'imatinib |
| RU2517216C2 (ru) * | 2012-08-22 | 2014-05-27 | Закрытое Акционерное Общество "БИОКАД" (ЗАО "БИОКАД") | Фармацевтическая композиция иматиниба или его фармацевтически приемлемой соли, способ ее получения и способ(ы) лечения |
| EP2749269A1 (fr) * | 2012-12-31 | 2014-07-02 | Deva Holding Anonim Sirketi | Procédé pour la préparation d'adsorbés de imatinib |
| AU2014226290B2 (en) * | 2013-03-04 | 2018-11-15 | Vtv Therapeutics Llc | Stable glucokinase activator compositions |
| EA029062B9 (ru) * | 2013-09-20 | 2018-05-31 | Тютор С.А.С.И.Ф.И.А. | Способ получения фармацевтической композиции и продукт способа |
| RU2551359C9 (ru) * | 2013-11-28 | 2021-08-20 | Общество с ограниченной ответственностью "Мамонт Фарм" | Наноразмерная слабо закристаллизованная модификация 4-метил-N-[3-(4-метилимидазол-1-ил)-5-(трифторметил)фенил]-3-[(4-пиридин-3-илпиримидин-2-ил)амино]бензамида гидрохлорида моногидрата, способ ее получения и фармацевтическая композиция на ее основе |
| CN104739785A (zh) * | 2013-12-25 | 2015-07-01 | 辰欣药业股份有限公司 | 一种具高溶出行为的甲磺酸伊马替尼片的组成及制备方法 |
| CN106856249B (zh) * | 2016-12-19 | 2019-07-09 | 河南超威电源有限公司 | 一种以阿拉伯胶作为稳定剂制备胶体电解液的方法 |
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| RU2020108342A (ru) | 2017-07-26 | 2021-08-26 | Эф Тэ Эф Фарма Привейт Лимитед | Жидкие дозируемые лекарственные формы иматиниба |
| CN108904809A (zh) * | 2018-08-20 | 2018-11-30 | 黎庆有 | 一种靶向抗肿瘤药物 |
| CN110664757B (zh) * | 2018-11-19 | 2022-08-02 | 成都瑞沐生物医药科技有限公司 | 纳米晶滴眼剂、其制备方法及其应用 |
| BR112021023014A2 (pt) | 2019-05-16 | 2022-02-08 | Aerovate Therapeutics Inc | Formulações de imatinibe, fabricação, e usos das mesmas |
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| JP4611641B2 (ja) * | 2002-03-20 | 2011-01-12 | エラン ファーマ インターナショナル，リミティド | Ｍａｐキナーゼ阻害剤のナノ粒子組成物 |
| CA2479665C (fr) * | 2002-03-20 | 2011-08-30 | Elan Pharma International Ltd. | Compositions nanoparticulaires d'inhibiteurs d'angiogenese |
| US9101540B2 (en) * | 2002-04-12 | 2015-08-11 | Alkermes Pharma Ireland Limited | Nanoparticulate megestrol formulations |
| US20040105889A1 (en) * | 2002-12-03 | 2004-06-03 | Elan Pharma International Limited | Low viscosity liquid dosage forms |
| AU2003234452A1 (en) * | 2002-05-06 | 2003-11-11 | Elan Pharma International Ltd. | Nanoparticulate nystatin formulations |
| AU2003241478A1 (en) * | 2002-06-10 | 2003-12-22 | Elan Pharma International, Ltd. | Nanoparticulate sterol formulations and sterol combinations |
| TWI307626B (en) * | 2002-08-20 | 2009-03-21 | Bristol Myers Squibb Co | Aripiprazole complex formulation and method |
| ATE487470T1 (de) * | 2002-09-11 | 2010-11-15 | Elan Pharma Int Ltd | Gel-stabilisierte wirkstoff-zusammensetzungen in nanoteilchengrösse |
| AU2003275329B2 (en) * | 2002-09-13 | 2008-04-03 | Cydex Pharmaceuticals, Inc. | Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin |
| EP1545536A4 (fr) * | 2002-09-19 | 2009-11-11 | Univ South Florida | Procede de traitement de la leucemie au moyen d'une combinaison d'acide hydromaxique suberoylanilide et d'imatinibe mesylate |
| WO2004032980A1 (fr) * | 2002-10-04 | 2004-04-22 | Elan Pharma International Limited | Irradiation gamma d'agents actifs nanoparticulaires solides |
| ATE514418T1 (de) * | 2002-11-12 | 2011-07-15 | Elan Pharma Int Ltd | Rasch zerfallende feste darreichungsformen mit nichtbröseliger konsistenz und pullulan |
| US20040208833A1 (en) * | 2003-02-04 | 2004-10-21 | Elan Pharma International Ltd. | Novel fluticasone formulations |
| US20050042177A1 (en) * | 2003-07-23 | 2005-02-24 | Elan Pharma International Ltd. | Novel compositions of sildenafil free base |
| ES2318330T3 (es) * | 2003-08-08 | 2009-05-01 | Elan Pharma International Limited | Nuevas composiciones de metaxalona. |
| ES2366646T3 (es) * | 2003-11-05 | 2011-10-24 | Elan Pharma International Limited | Composiciones en forma de nanopartículas que tienen un péptido como estabilizante superficial. |
| US20050147664A1 (en) * | 2003-11-13 | 2005-07-07 | Elan Pharma International Ltd. | Compositions comprising antibodies and methods of using the same for targeting nanoparticulate active agent delivery |
| WO2006054314A1 (fr) * | 2004-11-17 | 2006-05-26 | Natco Pharma Limited | Formes polymorphes de mesylate d'imatinibe |
| BRPI0607537A2 (pt) * | 2005-04-12 | 2009-09-15 | Elan Pharma Int Ltd | formulações de derivado de quinazolina nanoparticulado |
-
2006
- 2006-06-05 BR BRPI0613540-4A patent/BRPI0613540A2/pt not_active Application Discontinuation
- 2006-06-05 EA EA200702641A patent/EA015102B1/ru not_active IP Right Cessation
- 2006-06-05 CN CNA2006800283292A patent/CN101232870A/zh active Pending
- 2006-06-05 AT AT06772091T patent/ATE459341T1/de not_active IP Right Cessation
- 2006-06-05 KR KR1020077030987A patent/KR20080017067A/ko not_active Application Discontinuation
- 2006-06-05 AU AU2006255177A patent/AU2006255177A1/en not_active Abandoned
- 2006-06-05 MX MX2007015309A patent/MX2007015309A/es active IP Right Grant
- 2006-06-05 CA CA002610448A patent/CA2610448A1/fr not_active Abandoned
- 2006-06-05 JP JP2008514949A patent/JP2008542397A/ja active Pending
- 2006-06-05 EP EP06772091A patent/EP1895984B8/fr active Active
- 2006-06-05 EA EA201100022A patent/EA201100022A1/ru unknown
- 2006-06-05 DE DE602006012671T patent/DE602006012671D1/de active Active
- 2006-06-05 WO PCT/US2006/021657 patent/WO2006133046A2/fr active Application Filing
- 2006-06-05 ES ES06772091T patent/ES2341996T3/es active Active
- 2006-06-05 US US11/446,565 patent/US20060275372A1/en not_active Abandoned
-
2007
- 2007-12-03 IL IL187841A patent/IL187841A0/en unknown
- 2007-12-11 ZA ZA200710763A patent/ZA200710763B/xx unknown
- 2007-12-28 NO NO20076691A patent/NO20076691L/no not_active Application Discontinuation
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2008
- 2008-09-10 HK HK08110052.6A patent/HK1118467A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0613540A2 (pt) | 2011-01-18 |
| HK1118467A1 (en) | 2009-02-13 |
| ATE459341T1 (de) | 2010-03-15 |
| WO2006133046A2 (fr) | 2006-12-14 |
| EP1895984B1 (fr) | 2010-03-03 |
| EP1895984A2 (fr) | 2008-03-12 |
| EA015102B1 (ru) | 2011-06-30 |
| CN101232870A (zh) | 2008-07-30 |
| IL187841A0 (en) | 2008-03-20 |
| US20060275372A1 (en) | 2006-12-07 |
| AU2006255177A1 (en) | 2006-12-14 |
| EP1895984B8 (fr) | 2010-05-12 |
| MX2007015309A (es) | 2008-03-05 |
| EA200702641A1 (ru) | 2008-04-28 |
| KR20080017067A (ko) | 2008-02-25 |
| CA2610448A1 (fr) | 2006-12-14 |
| JP2008542397A (ja) | 2008-11-27 |
| ZA200710763B (en) | 2009-09-30 |
| WO2006133046A3 (fr) | 2007-07-26 |
| EA201100022A1 (ru) | 2011-06-30 |
| ES2341996T3 (es) | 2010-06-30 |
| DE602006012671D1 (de) | 2010-04-15 |
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