NO20076675L - Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet - Google Patents

Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet

Info

Publication number
NO20076675L
NO20076675L NO20076675A NO20076675A NO20076675L NO 20076675 L NO20076675 L NO 20076675L NO 20076675 A NO20076675 A NO 20076675A NO 20076675 A NO20076675 A NO 20076675A NO 20076675 L NO20076675 L NO 20076675L
Authority
NO
Norway
Prior art keywords
antibacterial activity
medicaments
humans
warm
bacterial infections
Prior art date
Application number
NO20076675A
Other languages
English (en)
Norwegian (no)
Inventor
Folkert Reck
Marshall Morningstar
Hajnalka Hartl
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20076675L publication Critical patent/NO20076675L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20076675A 2005-05-24 2007-12-27 Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet NO20076675L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68403005P 2005-05-24 2005-05-24
PCT/GB2006/001889 WO2006125974A1 (en) 2005-05-24 2006-05-23 Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity

Publications (1)

Publication Number Publication Date
NO20076675L true NO20076675L (no) 2007-12-27

Family

ID=36685663

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076675A NO20076675L (no) 2005-05-24 2007-12-27 Aminopiperidinquinoliner og deres azaisosteriske analoger med antibakteriell aktivitet

Country Status (14)

Country Link
US (1) US20090131444A1 (zh)
EP (1) EP1891078A1 (zh)
JP (1) JP2008542249A (zh)
KR (1) KR20080016577A (zh)
CN (1) CN101258157A (zh)
AU (1) AU2006250987A1 (zh)
BR (1) BRPI0609887A2 (zh)
CA (1) CA2608072A1 (zh)
IL (1) IL187134A0 (zh)
MX (1) MX2007014507A (zh)
NO (1) NO20076675L (zh)
RU (1) RU2007147413A (zh)
WO (1) WO2006125974A1 (zh)
ZA (1) ZA200709870B (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1996579A2 (en) * 2006-03-10 2008-12-03 Actelion Pharmaceuticals Ltd. Antibiotic compounds
US7709483B2 (en) 2006-04-06 2010-05-04 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
BRPI0712163A2 (pt) 2006-05-26 2012-03-13 Toyama Chemical Co., Ltd. composto, e, agente antimicrobiano
BRPI0712430A2 (pt) * 2006-06-08 2012-07-03 Speedel Experimenta Ag piperidinas 2,5-di-substitìdas.
BRPI0810064B8 (pt) * 2007-04-20 2021-05-25 Glaxo Group Ltd compostos contendo nitrogênio tricíclico como agentes antibacterianos, composições farmacêuticas que compreendem os ditos compostos e uso dos mesmos para o tratamento de infecções bacterianas em mamíferos
ES2370123T3 (es) * 2007-06-15 2011-12-12 Actelion Pharmaceuticals Ltd. Derivados de 3-amino-6-(1-aminoetil)-tetrahidropirano.
TW200940551A (en) 2008-02-20 2009-10-01 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
AU2009302075B2 (en) 2008-10-07 2015-04-16 Idorsia Pharmaceuticals Ltd Tricyclic oxazolidinone antibiotic compounds
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
CA2744456C (en) * 2008-12-12 2017-09-26 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
US20120053350A1 (en) * 2009-04-30 2012-03-01 Ian Mangion Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids
PE20171345A1 (es) 2010-04-02 2017-09-13 Senomyx Inc Modificador del sabor dulce
MX361020B (es) * 2011-06-17 2018-11-26 Pfizer Anti Infectives Ab Procesos para preparar compuestos heterociclicos, incluida trans-7-oxo-6-(sulfooxi)-1,6-diazabiciclo [3,2,1]octano-2-carboxam ida y sales de la misma.
MX336378B (es) 2011-08-12 2016-01-15 Senomyx Inc Modificador del sabor dulce.
RU2014143821A (ru) 2012-03-30 2016-05-27 Кьюбист Фармасьютикалз, Инк. 1, 3, 4-ОКСАДИАЗОЛЬНЫЕ И 1, 3, 4-ТИАДИАЗОЛЬНЫЕ ИНГИБИТОРЫ β-ЛАКТАМАЗЫ
AR090844A1 (es) * 2012-04-27 2014-12-10 Actelion Pharmaceuticals Ltd Proceso para elaborar derivados de naftiridina
WO2014152996A1 (en) 2013-03-14 2014-09-25 Cubist Pharmaceuticals, Inc. Crystalline form of a beta-lactamase inhibitor
US9120796B2 (en) 2013-10-02 2015-09-01 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
CN103613530B (zh) * 2013-12-02 2015-08-19 江苏弘和药物研发有限公司 一种芴甲氧羰基-3-哌啶醇的合成方法
CN105899487B (zh) 2013-12-27 2018-10-19 株式会社Api 5-羟基哌啶-2-甲酸的制造方法
ES2759303T3 (es) 2014-08-22 2020-05-08 Glaxosmithkline Ip Dev Ltd Compuestos tricíclicos que contienen nitrógeno para tratar infección por Neisseria gonorrhoeae
AU2015343463A1 (en) 2014-11-07 2017-06-15 Senomyx, Inc. Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers
UY36851A (es) * 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
MX2018015126A (es) * 2016-06-08 2019-09-02 Acraf Nuevos compuestos antibacterianos.
EP3484871B1 (en) 2016-07-13 2023-06-07 Syros Pharmaceuticals, Inc. Piperidine derivatives as inhibitors of cyclin dependent kinase 7 (cdk7)
CR20190595A (es) 2017-06-30 2020-03-03 Bayer Animal Health Gmbh Nuevos derivados de azaquinolina
IL272089B2 (en) 2017-08-09 2023-09-01 Denali Therapeutics Inc Compounds, preparations and methods
MA50063A (fr) * 2017-09-01 2021-04-28 Denali Therapeutics Inc Composés, compositions et procédés
JP7158393B2 (ja) 2017-09-14 2022-10-21 第一三共株式会社 環状構造を有する化合物
JP2022520236A (ja) 2019-02-13 2022-03-29 デナリ セラピューティクス インコーポレイテッド 化合物、組成物、及び、方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
IL154107A0 (en) * 2000-07-26 2003-07-31 Smithkline Beecham Plc Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
JP2004509885A (ja) * 2000-09-21 2004-04-02 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー 抗菌薬としてのキノリン誘導体
JP4887297B2 (ja) * 2004-09-24 2012-02-29 アクテリオン ファーマシューティカルズ リミテッド 新規二環式抗生物質

Also Published As

Publication number Publication date
KR20080016577A (ko) 2008-02-21
JP2008542249A (ja) 2008-11-27
CA2608072A1 (en) 2006-11-30
MX2007014507A (es) 2008-02-07
ZA200709870B (en) 2008-11-26
RU2007147413A (ru) 2009-06-27
AU2006250987A1 (en) 2006-11-30
CN101258157A (zh) 2008-09-03
US20090131444A1 (en) 2009-05-21
EP1891078A1 (en) 2008-02-27
WO2006125974A1 (en) 2006-11-30
IL187134A0 (en) 2008-02-09
BRPI0609887A2 (pt) 2011-10-11

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