ZA200709870B - Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity - Google Patents
Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activityInfo
- Publication number
- ZA200709870B ZA200709870B ZA200709870A ZA200709870A ZA200709870B ZA 200709870 B ZA200709870 B ZA 200709870B ZA 200709870 A ZA200709870 A ZA 200709870A ZA 200709870 A ZA200709870 A ZA 200709870A ZA 200709870 B ZA200709870 B ZA 200709870B
- Authority
- ZA
- South Africa
- Prior art keywords
- antibacterial activity
- aminopiperidine
- quinolines
- azaisosteric
- analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68403005P | 2005-05-24 | 2005-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200709870B true ZA200709870B (en) | 2008-11-26 |
Family
ID=36685663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200709870A ZA200709870B (en) | 2005-05-24 | 2007-11-15 | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090131444A1 (xx) |
| EP (1) | EP1891078A1 (xx) |
| JP (1) | JP2008542249A (xx) |
| KR (1) | KR20080016577A (xx) |
| CN (1) | CN101258157A (xx) |
| AU (1) | AU2006250987A1 (xx) |
| BR (1) | BRPI0609887A2 (xx) |
| CA (1) | CA2608072A1 (xx) |
| IL (1) | IL187134A0 (xx) |
| MX (1) | MX2007014507A (xx) |
| NO (1) | NO20076675L (xx) |
| RU (1) | RU2007147413A (xx) |
| WO (1) | WO2006125974A1 (xx) |
| ZA (1) | ZA200709870B (xx) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| EP1996579A2 (en) * | 2006-03-10 | 2008-12-03 | Actelion Pharmaceuticals Ltd. | Antibiotic compounds |
| DE602007009205D1 (de) | 2006-04-06 | 2010-10-28 | Glaxo Group Ltd | Pyrrolochinoxalinonderivate als antibakterielle mittel |
| KR101409261B1 (ko) | 2006-05-26 | 2014-06-18 | 다이쇼 세이야꾸 가부시끼가이샤 | 신규의 복소환 화합물 또는 그 염 및 그 중간체 |
| WO2007141318A1 (en) * | 2006-06-08 | 2007-12-13 | Speedel Experimenta Ag | 2,5-disubstituted piperidines |
| MY149347A (en) * | 2007-04-20 | 2013-08-30 | Glaxo Group Ltd | Tricyclic nitrogen containing compounds as antibacterial agents |
| ES2370123T3 (es) | 2007-06-15 | 2011-12-12 | Actelion Pharmaceuticals Ltd. | Derivados de 3-amino-6-(1-aminoetil)-tetrahidropirano. |
| MX2010008922A (es) | 2008-02-20 | 2010-09-07 | Actelion Pharmaceuticals Ltd | Compuestos antibioticos azatriciclicos. |
| CN104151316B (zh) | 2008-10-07 | 2016-06-15 | 埃科特莱茵药品有限公司 | 三环噁唑烷酮抗生素化合物 |
| JP2012505866A (ja) | 2008-10-17 | 2012-03-08 | グラクソ グループ リミテッド | 抗菌剤として使用される三環式窒素化合物 |
| MX2011005905A (es) * | 2008-12-12 | 2011-06-20 | Actelion Pharmaceuticals Ltd | Derivados de 5-amino-2-(1-hidroxi-etil)-tetrahidropirano. |
| US20120053350A1 (en) * | 2009-04-30 | 2012-03-01 | Ian Mangion | Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids |
| MY175079A (en) * | 2010-04-02 | 2020-06-04 | Firmenich Incorporated | Sweet flavor modifier |
| BR112013032415B1 (pt) * | 2011-06-17 | 2021-07-27 | Pfizer Anti-Infectives Ab | Processos para preparar compostos e compostos |
| MX336378B (es) | 2011-08-12 | 2016-01-15 | Senomyx Inc | Modificador del sabor dulce. |
| US8933232B2 (en) | 2012-03-30 | 2015-01-13 | Cubist Pharmaceuticals, Inc. | 1,3,4-oxadiazole and 1,3,4-thiadiazole beta-lactamase inhibitors |
| AR090844A1 (es) * | 2012-04-27 | 2014-12-10 | Actelion Pharmaceuticals Ltd | Proceso para elaborar derivados de naftiridina |
| WO2014152996A1 (en) | 2013-03-14 | 2014-09-25 | Cubist Pharmaceuticals, Inc. | Crystalline form of a beta-lactamase inhibitor |
| WO2015051101A1 (en) | 2013-10-02 | 2015-04-09 | Cubist Pharmaceuticals, Inc. | B-lactamase inhibitor picoline salt |
| CN103613530B (zh) * | 2013-12-02 | 2015-08-19 | 江苏弘和药物研发有限公司 | 一种芴甲氧羰基-3-哌啶醇的合成方法 |
| CN117886738A (zh) | 2013-12-27 | 2024-04-16 | 株式会社Api | 5-羟基哌啶-2-甲酸的制造方法 |
| BR112017003705B1 (pt) | 2014-08-22 | 2022-07-12 | Glaxosmithkline Intellectual Property Development Limited | Compostos contendo nitrogênio tricíclicos para o tratamento de infecção por neisseria gonorrhoea |
| BR112017008738B1 (pt) | 2014-11-07 | 2021-06-15 | Firmenich Incorporated | Ácidos 4-amino-5-(ciclohexilóxi)quinolina-3-carboxílicos substituídos como modificadores de sabores adoçantes |
| TW201722965A (zh) | 2015-08-16 | 2017-07-01 | 葛蘭素史密斯克藍智慧財產發展有限公司 | 用於抗菌應用之化合物 |
| US10633366B2 (en) * | 2016-06-08 | 2020-04-28 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Antibacterial compounds |
| WO2018013867A1 (en) | 2016-07-13 | 2018-01-18 | Marineau Jason J | Inhibitors of cyclin dependnt kinase 7 (cdk7) |
| KR20200020911A (ko) | 2017-06-30 | 2020-02-26 | 바이엘 애니멀 헬스 게엠베하 | 새로운 아자퀴놀린 유도체 |
| EP3665156A4 (en) | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc. | COMPOUNDS, COMPOSITIONS, AND PROCEDURES |
| EP4248965A3 (en) * | 2017-09-01 | 2023-11-22 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| AU2018333913B2 (en) | 2017-09-14 | 2022-11-17 | Daiichi Sankyo Company, Limited | Compound having cyclic structure |
| EP3924341A4 (en) | 2019-02-13 | 2022-11-02 | Denali Therapeutics Inc. | COMPOUNDS, COMPOSITIONS AND METHODS |
| CR20210426A (es) | 2019-02-13 | 2021-09-30 | Denali Therapeutics Inc | Compuestos, composiciones y métodos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9822450D0 (en) * | 1998-10-14 | 1998-12-09 | Smithkline Beecham Plc | Medicaments |
| PL366335A1 (en) * | 2000-07-26 | 2005-01-24 | Smithkline Beecham P.L.C. | Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity |
| EP1320529B1 (en) * | 2000-09-21 | 2006-05-24 | Smithkline Beecham Plc | Quinoline derivatives as antibacterials |
| WO2006032466A2 (en) * | 2004-09-24 | 2006-03-30 | Actelion Pharmaceuticals Ltd | New bicyclic antibiotics |
-
2006
- 2006-05-23 US US11/914,799 patent/US20090131444A1/en not_active Abandoned
- 2006-05-23 BR BRPI0609887-8A patent/BRPI0609887A2/pt not_active Application Discontinuation
- 2006-05-23 WO PCT/GB2006/001889 patent/WO2006125974A1/en active Application Filing
- 2006-05-23 JP JP2008512908A patent/JP2008542249A/ja active Pending
- 2006-05-23 AU AU2006250987A patent/AU2006250987A1/en not_active Abandoned
- 2006-05-23 KR KR1020077027342A patent/KR20080016577A/ko not_active Application Discontinuation
- 2006-05-23 CN CNA2006800266719A patent/CN101258157A/zh active Pending
- 2006-05-23 RU RU2007147413/04A patent/RU2007147413A/ru not_active Application Discontinuation
- 2006-05-23 EP EP06743966A patent/EP1891078A1/en not_active Withdrawn
- 2006-05-23 MX MX2007014507A patent/MX2007014507A/es not_active Application Discontinuation
- 2006-05-23 CA CA002608072A patent/CA2608072A1/en not_active Abandoned
-
2007
- 2007-11-04 IL IL187134A patent/IL187134A0/en unknown
- 2007-11-15 ZA ZA200709870A patent/ZA200709870B/xx unknown
- 2007-12-27 NO NO20076675A patent/NO20076675L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2608072A1 (en) | 2006-11-30 |
| EP1891078A1 (en) | 2008-02-27 |
| NO20076675L (no) | 2007-12-27 |
| MX2007014507A (es) | 2008-02-07 |
| AU2006250987A1 (en) | 2006-11-30 |
| BRPI0609887A2 (pt) | 2011-10-11 |
| RU2007147413A (ru) | 2009-06-27 |
| IL187134A0 (en) | 2008-02-09 |
| KR20080016577A (ko) | 2008-02-21 |
| WO2006125974A1 (en) | 2006-11-30 |
| CN101258157A (zh) | 2008-09-03 |
| US20090131444A1 (en) | 2009-05-21 |
| JP2008542249A (ja) | 2008-11-27 |
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