CR20190595A - Nuevos derivados de azaquinolina - Google Patents

Nuevos derivados de azaquinolina

Info

Publication number
CR20190595A
CR20190595A CR20190595A CR20190595A CR20190595A CR 20190595 A CR20190595 A CR 20190595A CR 20190595 A CR20190595 A CR 20190595A CR 20190595 A CR20190595 A CR 20190595A CR 20190595 A CR20190595 A CR 20190595A
Authority
CR
Costa Rica
Prior art keywords
compounds
new
azaquinoline
preparing
pharmaceutical compositions
Prior art date
Application number
CR20190595A
Other languages
English (en)
Inventor
Claudia Böhm
Kirsten Börngen
Thomas Ilg
Werner Hallenbach
Isa Jana Irina Janssen
Wei Zhuang
Daniel Kulke
Walter Hübsch
Iring Heisler
Nils Griebenow
Ulrich Görgens
Adeline Köhler
Bernd Alig
Hans-Georg Schwarz
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of CR20190595A publication Critical patent/CR20190595A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención abarca compuestos de azaquinolina de la fórmula general (I): (I), con A es A1 o A2: A1 A2 , y en la cual T, R1, R2, R3, R4, R5, R6, y Q son como se definen en el presente, procedimientos para la preparación de dichos compuestos, compuestos intermedios útiles para la preparación de dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para la elaboración de composiciones farmacéuticas para el tratamiento, control y/o prevención de enfermedades, en especial de infecciones con helmintos, como un único agente o en combinación con otros ingredientes activos.
CR20190595A 2017-06-30 2018-06-22 Nuevos derivados de azaquinolina CR20190595A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17179149 2017-06-30
PCT/EP2018/066776 WO2019002132A1 (en) 2017-06-30 2018-06-22 NEW AZAQUINOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
CR20190595A true CR20190595A (es) 2020-03-03

Family

ID=59269946

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20190595A CR20190595A (es) 2017-06-30 2018-06-22 Nuevos derivados de azaquinolina

Country Status (21)

Country Link
US (1) US11485733B2 (es)
EP (1) EP3615527B1 (es)
JP (1) JP7210483B2 (es)
KR (1) KR20200020911A (es)
CN (1) CN110770227B (es)
AR (1) AR112216A1 (es)
AU (1) AU2018293627B2 (es)
BR (1) BR112019028181A2 (es)
CA (1) CA3068350A1 (es)
CL (1) CL2019003892A1 (es)
CO (1) CO2019014484A2 (es)
CR (1) CR20190595A (es)
DK (1) DK3615527T3 (es)
IL (1) IL271607B2 (es)
MX (1) MX2019015895A (es)
PE (1) PE20200608A1 (es)
PH (1) PH12019502851A1 (es)
TW (1) TWI799429B (es)
UA (1) UA125800C2 (es)
UY (1) UY37789A (es)
WO (1) WO2019002132A1 (es)

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CA3179528A1 (en) 2020-04-09 2021-10-14 Bayer Animal Health Gmbh Substituted condensed azines as anthelmintic compounds
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AU2021384833A1 (en) 2020-11-18 2023-06-15 Elanco Tiergesundheit Ag N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections
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Also Published As

Publication number Publication date
RU2020103733A3 (es) 2021-10-22
UY37789A (es) 2019-01-31
TW201904961A (zh) 2019-02-01
JP7210483B2 (ja) 2023-01-23
KR20200020911A (ko) 2020-02-26
IL271607B2 (en) 2023-07-01
CL2019003892A1 (es) 2020-07-10
US11485733B2 (en) 2022-11-01
AU2018293627A1 (en) 2019-12-12
EP3615527B1 (en) 2024-03-06
WO2019002132A1 (en) 2019-01-03
IL271607A (en) 2020-02-27
IL271607B1 (en) 2023-03-01
PH12019502851A1 (en) 2020-10-19
RU2020103733A (ru) 2021-07-30
US20200131175A1 (en) 2020-04-30
TWI799429B (zh) 2023-04-21
CA3068350A1 (en) 2019-01-03
BR112019028181A2 (pt) 2020-07-07
EP3615527A1 (en) 2020-03-04
MX2019015895A (es) 2020-02-07
CN110770227A (zh) 2020-02-07
AR112216A1 (es) 2019-10-02
CO2019014484A2 (es) 2020-01-17
DK3615527T3 (da) 2024-05-06
PE20200608A1 (es) 2020-03-10
AU2018293627B2 (en) 2022-07-21
JP2020525444A (ja) 2020-08-27
UA125800C2 (uk) 2022-06-08
CN110770227B (zh) 2024-03-01

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