NO20070764L - Fremgangsmate for fremstilling av liposomholdig preparat - Google Patents
Fremgangsmate for fremstilling av liposomholdig preparatInfo
- Publication number
- NO20070764L NO20070764L NO20070764A NO20070764A NO20070764L NO 20070764 L NO20070764 L NO 20070764L NO 20070764 A NO20070764 A NO 20070764A NO 20070764 A NO20070764 A NO 20070764A NO 20070764 L NO20070764 L NO 20070764L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- liposome
- liposomes
- carbon dioxide
- soluble drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
Fremgangsmåte for fremstilling av et liposomholdig preparat som inneholder liposomer med en forhøyet andel innesluttet legemiddel. Liposomene har utmerket stabilitet in vivo. Det beskrives også et liposomholdig preparat fremstilt ved fremgangsmåten. Fremgangsmåten er kjennetegnet ved at karbondioksid i superkritisk eller subkritisk tilstand, en liposommembranbestanddel som minst inneholder et fosfolipid som har en overgangstemperatur, og et vannløselig legemiddel blandes i en trykkbeholder, og ved å redusere trykket i beholderen fjernes karbondioksidet, og derved fremstilles en vandig dispersjon av liposomer med et innesluttet vannløselig legemiddel.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004234583 | 2004-08-11 | ||
JP2004252931 | 2004-08-31 | ||
JP2004261585 | 2004-09-08 | ||
PCT/JP2005/013309 WO2006016468A1 (ja) | 2004-08-11 | 2005-07-20 | リポソーム含有製剤の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20070764L true NO20070764L (no) | 2007-03-09 |
Family
ID=35800241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20070764A NO20070764L (no) | 2004-08-11 | 2007-02-08 | Fremgangsmate for fremstilling av liposomholdig preparat |
Country Status (5)
Country | Link |
---|---|
US (1) | US8480952B2 (no) |
EP (1) | EP1776948B1 (no) |
JP (1) | JP5176320B2 (no) |
NO (1) | NO20070764L (no) |
WO (1) | WO2006016468A1 (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060239925A1 (en) * | 2005-04-21 | 2006-10-26 | Konica Minolta Medical & Graphic, Inc. | Method of manufacturing pharmaceutical preparation containing liposomes |
JP2007261984A (ja) * | 2006-03-28 | 2007-10-11 | Konica Minolta Medical & Graphic Inc | 脂肪酸エステルを有するリポソ−ムおよびその製剤 |
EP3494964B1 (en) * | 2007-05-14 | 2021-04-07 | Konica Minolta Holdings, Inc. | Liposome and method for producing liposome |
WO2010019649A2 (en) * | 2008-08-13 | 2010-02-18 | Dow Global Technologies Inc. | Active polymer compositions |
US9445975B2 (en) * | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
CN101810610B (zh) * | 2010-04-19 | 2012-09-26 | 海南美兰史克制药有限公司 | 一种阿莫西林钠氟氯西林钠药物组合物脂质体注射剂 |
JP5832467B2 (ja) * | 2013-03-19 | 2015-12-16 | 株式会社富士薬品 | 無菌乳化システム |
AU2016256979B2 (en) * | 2015-05-04 | 2021-01-28 | Versantis AG | Method for preparing transmembrane pH-gradient vesicles |
US10556216B2 (en) * | 2016-05-26 | 2020-02-11 | Becton, Dickinson And Company | Methods and devices for liposome preparation by centrifugation |
JP7330488B2 (ja) * | 2018-05-10 | 2023-08-22 | 学校法人福岡大学 | リポソームの製造方法および製造装置 |
CN115804756B (zh) * | 2022-12-28 | 2024-04-05 | 山东中医药大学附属医院 | 超临界流体制备奥硝唑脂质体及其制剂 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4192859A (en) * | 1978-09-29 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Contrast media containing liposomes as carriers |
CH672733A5 (no) * | 1987-05-22 | 1989-12-29 | Bracco Ind Chimica Spa | |
EP0331504B1 (en) * | 1988-03-04 | 1992-06-10 | Takeda Chemical Industries, Ltd. | Liposome composition |
JPH01249717A (ja) * | 1988-03-30 | 1989-10-05 | Fuji Photo Film Co Ltd | リポソームの製造方法 |
US5277914A (en) * | 1989-03-31 | 1994-01-11 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
JP2854203B2 (ja) * | 1992-09-03 | 1999-02-03 | 株式会社ディ・ディ・エス研究所 | リポソームの製造法 |
DK0665743T3 (da) * | 1992-10-14 | 2002-04-08 | Liposome Co Inc | Interdigitationsfusions-liposomer og -geler |
US5326552A (en) * | 1992-12-17 | 1994-07-05 | Sterling Winthrop Inc. | Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants |
US5340614A (en) * | 1993-02-11 | 1994-08-23 | Minnesota Mining And Manufacturing Company | Methods of polymer impregnation |
DE59406065D1 (de) * | 1993-03-24 | 1998-07-02 | Ciba Geigy Ag | Verfahren zur Herstellung einer Liposomendispersion im Hochdruckbereich |
US5554382A (en) * | 1993-05-28 | 1996-09-10 | Aphios Corporation | Methods and apparatus for making liposomes |
JP3498339B2 (ja) * | 1993-12-16 | 2004-02-16 | 日本油脂株式会社 | リン脂質誘導体 |
ATE223205T1 (de) * | 1994-11-18 | 2002-09-15 | Aphios Corp | Verfahren zur herstellung von liposomen, die hydrophobische artzneistoffe enthalten |
CA2212162A1 (en) * | 1995-02-09 | 1996-08-15 | Schering Aktiengesellschaft | Liposomes that contain contrast media for the visualization of intravascular space |
US6270806B1 (en) * | 1999-03-03 | 2001-08-07 | Elan Pharma International Limited | Use of peg-derivatized lipids as surface stabilizers for nanoparticulate compositions |
JP4710109B2 (ja) * | 2000-07-24 | 2011-06-29 | 日油株式会社 | ポリアルキレンオキシド修飾リン脂質、その製造方法および用途 |
EP1334765B1 (en) * | 2000-10-13 | 2010-06-30 | National Institute of Advanced Industrial Science and Technology | Process for producing liposome |
JP2003119120A (ja) * | 2001-10-12 | 2003-04-23 | Masahiko Abe | リポソームの製造方法、及び該リポソームを含有する化粧料、及び皮膚外用剤 |
CN1218746C (zh) * | 2002-04-12 | 2005-09-14 | 中国农业大学 | 药物靶向脂质体的制备方法 |
JP2005170923A (ja) * | 2003-10-21 | 2005-06-30 | Konica Minolta Medical & Graphic Inc | リポソーム含有x線造影剤およびその製造方法 |
JP2005170928A (ja) * | 2003-10-21 | 2005-06-30 | Konica Minolta Medical & Graphic Inc | リポソーム含有x線造影剤およびその製造方法 |
JP4595319B2 (ja) * | 2003-12-03 | 2010-12-08 | コニカミノルタエムジー株式会社 | リポソーム用脂質、リポソームおよびそれらの製造方法 |
JP2005220034A (ja) * | 2004-02-03 | 2005-08-18 | Konica Minolta Medical & Graphic Inc | X線検査用造影剤の製造方法 |
JP2005255588A (ja) * | 2004-03-10 | 2005-09-22 | Konica Minolta Medical & Graphic Inc | リポソーム含有x線造影剤 |
-
2005
- 2005-07-20 WO PCT/JP2005/013309 patent/WO2006016468A1/ja active Application Filing
- 2005-07-20 JP JP2006531374A patent/JP5176320B2/ja not_active Expired - Fee Related
- 2005-07-20 EP EP05766258.7A patent/EP1776948B1/en not_active Expired - Fee Related
- 2005-07-22 US US11/187,397 patent/US8480952B2/en not_active Expired - Fee Related
-
2007
- 2007-02-08 NO NO20070764A patent/NO20070764L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2006016468A1 (ja) | 2006-02-16 |
EP1776948A1 (en) | 2007-04-25 |
US20060034907A1 (en) | 2006-02-16 |
US8480952B2 (en) | 2013-07-09 |
EP1776948B1 (en) | 2015-12-09 |
JPWO2006016468A1 (ja) | 2008-05-01 |
EP1776948A4 (en) | 2012-06-20 |
JP5176320B2 (ja) | 2013-04-03 |
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