NO20070192L - Fremgangsmater for a oppna paclitaxel fra taxusplanter - Google Patents

Fremgangsmater for a oppna paclitaxel fra taxusplanter

Info

Publication number
NO20070192L
NO20070192L NO20070192A NO20070192A NO20070192L NO 20070192 L NO20070192 L NO 20070192L NO 20070192 A NO20070192 A NO 20070192A NO 20070192 A NO20070192 A NO 20070192A NO 20070192 L NO20070192 L NO 20070192L
Authority
NO
Norway
Prior art keywords
paclitaxel
methods
plants containing
obtaining
taxus plants
Prior art date
Application number
NO20070192A
Other languages
English (en)
Inventor
Bruno Gabetta
Gianfranco Zini
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20070192L publication Critical patent/NO20070192L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Fremgangsmåter for å oppnå paclitaxel fra planter inneholdende paclitaxel er beskrevet. Plantemateriale oppnås først fra planter inneholdende paclitaxel. Paclitaxel ekstraheres deretter fra plantematerialet. Deretter separeres paclitaxel fra paclitaxelekstrakten ved anvendelse av en serie av kolonnekromatografiseparasjons-trinn for å oppnå minst én fraksjon inneholdende paclitaxel. Paclitaxel i en fraksjon som oppnås fra det siste kromatografitrinnet krystalliseres. Ved anvendelse av disse fremgangsmåtene kan paclitaxel av høy renhet effektivt oppnås fra planter inneholdende paclitaxel.
NO20070192A 2004-07-13 2007-01-11 Fremgangsmater for a oppna paclitaxel fra taxusplanter NO20070192L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04016493A EP1616868B1 (en) 2004-07-13 2004-07-13 Methods for obtaining paclitaxel from taxus plants
PCT/EP2005/006846 WO2006005429A1 (en) 2004-07-13 2005-06-24 Methods for obtaining paclitaxel from taxus plants

Publications (1)

Publication Number Publication Date
NO20070192L true NO20070192L (no) 2007-02-13

Family

ID=34925739

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070192A NO20070192L (no) 2004-07-13 2007-01-11 Fremgangsmater for a oppna paclitaxel fra taxusplanter

Country Status (20)

Country Link
EP (1) EP1616868B1 (no)
JP (1) JP4890455B2 (no)
KR (1) KR101142565B1 (no)
CN (1) CN100546986C (no)
AT (1) ATE372993T1 (no)
AU (1) AU2005261970B2 (no)
CA (1) CA2573601C (no)
CY (1) CY1107803T1 (no)
DE (1) DE602004008903T2 (no)
DK (1) DK1616868T3 (no)
ES (1) ES2293129T3 (no)
HK (1) HK1101822A1 (no)
IL (1) IL180643A (no)
NO (1) NO20070192L (no)
NZ (1) NZ552549A (no)
PL (1) PL1616868T3 (no)
PT (1) PT1616868E (no)
RU (1) RU2373198C2 (no)
SI (1) SI1616868T1 (no)
WO (1) WO2006005429A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102250047B (zh) * 2011-08-26 2013-06-05 贺金凤 一种紫杉醇化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1258838B (it) * 1992-01-31 1996-02-29 Indena Spa Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus
US6136989A (en) * 1998-12-30 2000-10-24 Phytogen Life Sciences, Incorporated Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
US5969165A (en) * 1999-01-07 1999-10-19 508037 (Nb) Inc. Isolation and purification of paclitaxel and other related taxanes by industrial preparative low pressure chromatography on a polymeric resin column
CA2299149C (fr) * 1999-06-22 2010-09-21 Chaichem Pharmaceuticals International Procede d'isolation et de purification du paclitaxel a partir de sources naturelles
US6452024B1 (en) * 2000-02-22 2002-09-17 Chaichem Pharmaceuticals International Process for extraction and purification of paclitaxel from natural sources
US6229027B1 (en) * 2000-03-10 2001-05-08 Jian Liu Process for manufacturing paclitaxel and 13-acetyl-9-dihydrobaccatin IV
US6333419B1 (en) * 2000-11-28 2001-12-25 Indena Spa Chromatographic separation method of paclitaxel and cephalomannin

Also Published As

Publication number Publication date
ES2293129T3 (es) 2008-03-16
KR101142565B1 (ko) 2012-05-03
HK1101822A1 (en) 2007-10-26
EP1616868B1 (en) 2007-09-12
EP1616868A1 (en) 2006-01-18
CY1107803T1 (el) 2013-06-19
DE602004008903D1 (de) 2007-10-25
CN100546986C (zh) 2009-10-07
WO2006005429A1 (en) 2006-01-19
NZ552549A (en) 2008-12-24
RU2373198C2 (ru) 2009-11-20
DK1616868T3 (da) 2008-01-21
JP4890455B2 (ja) 2012-03-07
ATE372993T1 (de) 2007-09-15
AU2005261970A1 (en) 2006-01-19
JP2008505946A (ja) 2008-02-28
IL180643A0 (en) 2007-06-03
PL1616868T3 (pl) 2008-02-29
SI1616868T1 (sl) 2008-02-29
AU2005261970B2 (en) 2011-04-21
CA2573601C (en) 2012-12-18
PT1616868E (pt) 2007-12-10
DE602004008903T2 (de) 2008-06-19
KR20060005958A (ko) 2006-01-18
CA2573601A1 (en) 2006-01-19
CN1984896A (zh) 2007-06-20
IL180643A (en) 2010-12-30
RU2007101233A (ru) 2008-08-20

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