NO20064295L - Bruk av metylenamidderivater i kardiovaskulaere lidelser - Google Patents
Bruk av metylenamidderivater i kardiovaskulaere lidelserInfo
- Publication number
- NO20064295L NO20064295L NO20064295A NO20064295A NO20064295L NO 20064295 L NO20064295 L NO 20064295L NO 20064295 A NO20064295 A NO 20064295A NO 20064295 A NO20064295 A NO 20064295A NO 20064295 L NO20064295 L NO 20064295L
- Authority
- NO
- Norway
- Prior art keywords
- cardiovascular disorders
- derivatives
- methylenamide
- prevention
- formula
- Prior art date
Links
- WDWDWGRYHDPSDS-UHFFFAOYSA-N methanimine Chemical class N=C WDWDWGRYHDPSDS-UHFFFAOYSA-N 0.000 title abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 206010048554 Endothelial dysfunction Diseases 0.000 abstract 1
- 230000008694 endothelial dysfunction Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Den foreliggende oppfinnelsen gjelder anvendelsen av substituerte metylenamidderivater med formel (I) for behandling og/eller forebygging av kardiovaskulære lidelser som koronar obstruksjon og hjertesvikt. Spesielt gjelder den foreliggende oppfinnelsen anvendelsen av substituerte metylenamidderivater med formel (I) spesielt for behandling og/eller forebygging av endotelisk dysfunksjon ved hjertesvikt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04100778 | 2004-02-27 | ||
PCT/EP2005/050823 WO2005082347A1 (en) | 2004-02-27 | 2005-02-25 | Use of methylene amide derivatives in cardiovascular disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20064295L true NO20064295L (no) | 2006-09-22 |
Family
ID=34896106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20064295A NO20064295L (no) | 2004-02-27 | 2006-09-22 | Bruk av metylenamidderivater i kardiovaskulaere lidelser |
Country Status (24)
Country | Link |
---|---|
US (1) | US20070185118A1 (no) |
EP (1) | EP1732534B1 (no) |
JP (1) | JP5001138B2 (no) |
KR (1) | KR101188940B1 (no) |
CN (1) | CN1933827B (no) |
AT (1) | ATE401877T1 (no) |
AU (1) | AU2005216649B2 (no) |
BR (1) | BRPI0508080A (no) |
CA (1) | CA2554919C (no) |
CY (1) | CY1108252T1 (no) |
DE (1) | DE602005008412D1 (no) |
DK (1) | DK1732534T3 (no) |
EA (1) | EA011811B1 (no) |
ES (1) | ES2308458T3 (no) |
HK (1) | HK1098073A1 (no) |
HR (1) | HRP20080367T3 (no) |
IL (1) | IL177494A (no) |
NO (1) | NO20064295L (no) |
PL (1) | PL1732534T3 (no) |
PT (1) | PT1732534E (no) |
RS (1) | RS50596B (no) |
SI (1) | SI1732534T1 (no) |
UA (1) | UA84453C2 (no) |
WO (1) | WO2005082347A1 (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE510817T1 (de) * | 2002-01-29 | 2011-06-15 | Merck Serono Sa | Substituierte methylenamidderivate als modulatoren von proteintyrosinphosphatasen (ptps) |
ES2337150T3 (es) | 2003-07-21 | 2010-04-21 | Merck Serono Sa | Alquinilaril carboxamidas. |
WO2008044731A1 (fr) | 2006-10-12 | 2008-04-17 | Institute Of Medicinal Molecular Design. Inc. | Dérivé d'acide n-phényloxamidique |
US8633245B2 (en) * | 2008-04-11 | 2014-01-21 | Institute Of Medicinal Molecular Design, Inc. | PAI-1 inhibitor |
US8906258B2 (en) | 2011-08-29 | 2014-12-09 | Ticona Llc | Heat-resistant liquid crystalline polymer composition having a low melting temperature |
US9045685B2 (en) | 2011-08-29 | 2015-06-02 | Ticona Llc | Cast molded parts formed from a liquid crystalline polymer |
KR20140057629A (ko) | 2011-08-29 | 2014-05-13 | 티코나 엘엘씨 | 방향족 아마이드 화합물 |
WO2013032975A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | Thermotropic liquid crystalline polymer with improved low shear viscosity |
TW201313884A (zh) | 2011-08-29 | 2013-04-01 | Ticona Llc | 液晶聚合物之固態聚合 |
US8852730B2 (en) | 2011-08-29 | 2014-10-07 | Ticona Llc | Melt-extruded substrate for use in thermoformed articles |
WO2013032981A1 (en) | 2011-08-29 | 2013-03-07 | Ticona Llc | High flow liquid crystalline polymer composition |
JP2014525500A (ja) | 2011-08-29 | 2014-09-29 | ティコナ・エルエルシー | 低溶融粘度液晶ポリマーの溶融重合 |
TW201319223A (zh) | 2011-08-29 | 2013-05-16 | Ticona Llc | 高流量液晶聚合物組合物 |
WO2014095815A1 (en) | 2012-12-17 | 2014-06-26 | Shell Internationale Research Maatschappij B.V. | Integrated gas-to-liquid condensate process |
WO2014130275A2 (en) | 2013-02-22 | 2014-08-28 | Ticona Llc | High performance polymer composition with improved flow properties |
US9206300B2 (en) | 2013-06-07 | 2015-12-08 | Ticona Llc | High strength thermotropic liquid crystalline polymer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6985200A (en) * | 1999-09-10 | 2001-04-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (ptpases) |
US6627767B2 (en) * | 2000-08-29 | 2003-09-30 | Abbott Laboratories | Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors |
DE10117823A1 (de) * | 2001-04-10 | 2002-10-17 | Merck Patent Gmbh | Oxalsäurederivate |
WO2002098408A1 (en) * | 2001-06-07 | 2002-12-12 | Wyeth | Ptpase inhibitors for improving cardiovascular risk profile |
AR034374A1 (es) * | 2001-06-07 | 2004-02-18 | Wyeth Corp | Combinacion de un inhibidor de ptpasa y un inhibidor de ace |
ATE510817T1 (de) * | 2002-01-29 | 2011-06-15 | Merck Serono Sa | Substituierte methylenamidderivate als modulatoren von proteintyrosinphosphatasen (ptps) |
-
2005
- 2005-02-25 US US10/590,808 patent/US20070185118A1/en not_active Abandoned
- 2005-02-25 JP JP2007500226A patent/JP5001138B2/ja not_active Expired - Fee Related
- 2005-02-25 BR BRPI0508080-0A patent/BRPI0508080A/pt not_active IP Right Cessation
- 2005-02-25 EA EA200601511A patent/EA011811B1/ru not_active IP Right Cessation
- 2005-02-25 UA UAA200609879A patent/UA84453C2/ru unknown
- 2005-02-25 EP EP05716814A patent/EP1732534B1/en active Active
- 2005-02-25 ES ES05716814T patent/ES2308458T3/es active Active
- 2005-02-25 AT AT05716814T patent/ATE401877T1/de active
- 2005-02-25 PL PL05716814T patent/PL1732534T3/pl unknown
- 2005-02-25 KR KR1020067019715A patent/KR101188940B1/ko not_active IP Right Cessation
- 2005-02-25 PT PT05716814T patent/PT1732534E/pt unknown
- 2005-02-25 DK DK05716814T patent/DK1732534T3/da active
- 2005-02-25 CN CN2005800087220A patent/CN1933827B/zh not_active Expired - Fee Related
- 2005-02-25 SI SI200530349T patent/SI1732534T1/sl unknown
- 2005-02-25 AU AU2005216649A patent/AU2005216649B2/en not_active Ceased
- 2005-02-25 CA CA2554919A patent/CA2554919C/en not_active Expired - Fee Related
- 2005-02-25 RS RSP-2008/0353A patent/RS50596B/sr unknown
- 2005-02-25 WO PCT/EP2005/050823 patent/WO2005082347A1/en active Application Filing
- 2005-02-25 DE DE602005008412T patent/DE602005008412D1/de active Active
-
2006
- 2006-08-15 IL IL177494A patent/IL177494A/en not_active IP Right Cessation
- 2006-09-22 NO NO20064295A patent/NO20064295L/no not_active Application Discontinuation
-
2007
- 2007-05-28 HK HK07105603.1A patent/HK1098073A1/xx not_active IP Right Cessation
-
2008
- 2008-07-24 HR HR20080367T patent/HRP20080367T3/xx unknown
- 2008-08-11 CY CY20081100844T patent/CY1108252T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1933827A (zh) | 2007-03-21 |
EP1732534A1 (en) | 2006-12-20 |
CA2554919A1 (en) | 2005-09-09 |
UA84453C2 (ru) | 2008-10-27 |
PL1732534T3 (pl) | 2008-12-31 |
JP2007524701A (ja) | 2007-08-30 |
KR20060129066A (ko) | 2006-12-14 |
EP1732534B1 (en) | 2008-07-23 |
DE602005008412D1 (de) | 2008-09-04 |
ATE401877T1 (de) | 2008-08-15 |
WO2005082347A1 (en) | 2005-09-09 |
BRPI0508080A (pt) | 2007-07-17 |
PT1732534E (pt) | 2008-08-08 |
IL177494A0 (en) | 2006-12-31 |
EA200601511A1 (ru) | 2007-02-27 |
CA2554919C (en) | 2013-04-16 |
JP5001138B2 (ja) | 2012-08-15 |
RS50596B (sr) | 2010-05-07 |
HRP20080367T3 (en) | 2008-09-30 |
AU2005216649A1 (en) | 2005-09-09 |
DK1732534T3 (da) | 2008-11-17 |
EA011811B1 (ru) | 2009-06-30 |
AU2005216649B2 (en) | 2010-09-09 |
US20070185118A1 (en) | 2007-08-09 |
ES2308458T3 (es) | 2008-12-01 |
IL177494A (en) | 2011-06-30 |
HK1098073A1 (en) | 2007-07-13 |
SI1732534T1 (sl) | 2008-10-31 |
CY1108252T1 (el) | 2014-02-12 |
CN1933827B (zh) | 2011-07-27 |
KR101188940B1 (ko) | 2012-10-08 |
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Legal Events
Date | Code | Title | Description |
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CREP | Change of representative |
Representative=s name: ONSAGERS AS, POSTBOKS 6963 ST OLAVS PLASS, 0130 OS |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |